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- W3115367881 abstract "A convenient practical approach for the synthesis of 2-(pyridin-2-yl)ethanols by direct benzylic addition of azaarenes and aldehydes under catalyst- and solvent-free conditions is reported. This reaction is metal-free, green, and was carried out in a facile operative environment without using any hazardous transition metal catalysts or any other coupling reagents. Different aromatic aldehydes and azaarenes were monitored, and the yields of the resulting products were moderate to excellent. We accomplished several azaarene derivatives under neat conditions through a highly atom-economical pathway. To evaluate the preparative potential of this process, gram-scale reactions were performed up to a 10 g scale." @default.
- W3115367881 created "2021-01-05" @default.
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- W3115367881 date "2020-12-23" @default.
- W3115367881 modified "2023-10-14" @default.
- W3115367881 title "An atom-economical addition of methyl azaarenes with aromatic aldehydes via benzylic C(sp3)–H bond functionalization under solvent- and catalyst-free conditions" @default.
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- W3115367881 doi "https://doi.org/10.3762/bjoc.16.259" @default.
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