Matches in SemOpenAlex for { <https://semopenalex.org/work/W3115663775> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3115663775 endingPage "66" @default.
- W3115663775 startingPage "55" @default.
- W3115663775 abstract "Aim: To compare safety (immunogenicity) and efficacy of a biosimilar insulin GP-Lis25 and a reference insulin Ly-Lis25 (Humalog Mix 25) in Type 2 diabetes mellitus (T2D) patients. Materials & methods: This randomized open-label, 26-week clinical trial enrolled 210 T2D patients, randomized 1:1 to twice-daily GP-Lis25 or Ly-Lis25. The primary end point was immune response at 26th week. Noninferiority margin for HbA1c was 0.4%. Results: Immune response frequency was similar in GP-Lis25 and Ly-Lis25 groups both at week 12 (p = 0.651) and 26 (p = 0.164). The difference of HbA1c change at week 26 was (95% CI) 0.01 (-0.27–0.28)%. Fasting plasma glucose, seven-point glucose profile and insulin dose were similar between groups. Safety did not differ between groups. Conclusion: GP-Lis25 and Ly-Lis25 demonstrated similar safety and efficacy. ClincalTrials.gov identifier: NCT04023344 ." @default.
- W3115663775 created "2021-01-05" @default.
- W3115663775 creator A5009071256 @default.
- W3115663775 creator A5022584888 @default.
- W3115663775 creator A5024324782 @default.
- W3115663775 creator A5024698048 @default.
- W3115663775 creator A5050644013 @default.
- W3115663775 creator A5063416659 @default.
- W3115663775 creator A5074524605 @default.
- W3115663775 creator A5078843883 @default.
- W3115663775 creator A5087695883 @default.
- W3115663775 creator A5087750332 @default.
- W3115663775 date "2021-01-01" @default.
- W3115663775 modified "2023-10-18" @default.
- W3115663775 title "Efficacy and safety of GP40021 insulin lispro biphasic compared with Humalog Mix 25 in Type 2 diabetes mellitus patients" @default.
- W3115663775 cites W2912984905 @default.
- W3115663775 cites W2916840078 @default.
- W3115663775 cites W2917193598 @default.
- W3115663775 cites W2973549687 @default.
- W3115663775 cites W3030870443 @default.
- W3115663775 cites W4292528167 @default.
- W3115663775 doi "https://doi.org/10.2217/cer-2020-0064" @default.
- W3115663775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33355484" @default.
- W3115663775 hasPublicationYear "2021" @default.
- W3115663775 type Work @default.
- W3115663775 sameAs 3115663775 @default.
- W3115663775 citedByCount "2" @default.
- W3115663775 countsByYear W31156637752022 @default.
- W3115663775 crossrefType "journal-article" @default.
- W3115663775 hasAuthorship W3115663775A5009071256 @default.
- W3115663775 hasAuthorship W3115663775A5022584888 @default.
- W3115663775 hasAuthorship W3115663775A5024324782 @default.
- W3115663775 hasAuthorship W3115663775A5024698048 @default.
- W3115663775 hasAuthorship W3115663775A5050644013 @default.
- W3115663775 hasAuthorship W3115663775A5063416659 @default.
- W3115663775 hasAuthorship W3115663775A5074524605 @default.
- W3115663775 hasAuthorship W3115663775A5078843883 @default.
- W3115663775 hasAuthorship W3115663775A5087695883 @default.
- W3115663775 hasAuthorship W3115663775A5087750332 @default.
- W3115663775 hasConcept C126322002 @default.
- W3115663775 hasConcept C134018914 @default.
- W3115663775 hasConcept C168563851 @default.
- W3115663775 hasConcept C203014093 @default.
- W3115663775 hasConcept C203092338 @default.
- W3115663775 hasConcept C2776486108 @default.
- W3115663775 hasConcept C2777180221 @default.
- W3115663775 hasConcept C2778199505 @default.
- W3115663775 hasConcept C2779306644 @default.
- W3115663775 hasConcept C2780868878 @default.
- W3115663775 hasConcept C2910068830 @default.
- W3115663775 hasConcept C555293320 @default.
- W3115663775 hasConcept C71924100 @default.
- W3115663775 hasConcept C8891405 @default.
- W3115663775 hasConceptScore W3115663775C126322002 @default.
- W3115663775 hasConceptScore W3115663775C134018914 @default.
- W3115663775 hasConceptScore W3115663775C168563851 @default.
- W3115663775 hasConceptScore W3115663775C203014093 @default.
- W3115663775 hasConceptScore W3115663775C203092338 @default.
- W3115663775 hasConceptScore W3115663775C2776486108 @default.
- W3115663775 hasConceptScore W3115663775C2777180221 @default.
- W3115663775 hasConceptScore W3115663775C2778199505 @default.
- W3115663775 hasConceptScore W3115663775C2779306644 @default.
- W3115663775 hasConceptScore W3115663775C2780868878 @default.
- W3115663775 hasConceptScore W3115663775C2910068830 @default.
- W3115663775 hasConceptScore W3115663775C555293320 @default.
- W3115663775 hasConceptScore W3115663775C71924100 @default.
- W3115663775 hasConceptScore W3115663775C8891405 @default.
- W3115663775 hasIssue "1" @default.
- W3115663775 hasLocation W31156637751 @default.
- W3115663775 hasOpenAccess W3115663775 @default.
- W3115663775 hasPrimaryLocation W31156637751 @default.
- W3115663775 hasRelatedWork W1973522969 @default.
- W3115663775 hasRelatedWork W2010921056 @default.
- W3115663775 hasRelatedWork W2016476819 @default.
- W3115663775 hasRelatedWork W2039442988 @default.
- W3115663775 hasRelatedWork W2076107635 @default.
- W3115663775 hasRelatedWork W2136047525 @default.
- W3115663775 hasRelatedWork W3046305017 @default.
- W3115663775 hasRelatedWork W3153783058 @default.
- W3115663775 hasRelatedWork W4239673060 @default.
- W3115663775 hasRelatedWork W4240828045 @default.
- W3115663775 hasVolume "10" @default.
- W3115663775 isParatext "false" @default.
- W3115663775 isRetracted "false" @default.
- W3115663775 magId "3115663775" @default.
- W3115663775 workType "article" @default.