FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3115668845> ?p ?o ?g. }

• W3115668845 endingPage "58368" @default.
• W3115668845 startingPage "58360" @default.
• W3115668845 abstract "The SARS-CoV-2 virus that causes the COVID-19 epidemic can be transmitted via respiratory droplet-contaminated surfaces or fomites, which urgently requires a fundamental understanding of intermolecular interactions of the coronavirus with various surfaces. The corona-like component of the outer surface of the SARS-CoV-2 virion, named spike protein, is a key target for the adsorption and persistence of SARS-CoV-2 on various surfaces. However, a lack of knowledge in intermolecular interactions between spike protein and different substrate surfaces has resulted in ineffective preventive measures and inaccurate information. Herein, we quantified the surface interaction and adhesion energy of SARS-CoV-2 spike protein with a series of inanimate surfaces via atomic force microscopy under a simulated respiratory droplet environment. Among four target surfaces, polystyrene was found to exhibit the strongest adhesion, followed by stainless steel (SS), gold, and glass. The environmental factors (e.g., pH and temperature) played a role in mediating the spike protein binding. According to systematic quantification on a series of inanimate surfaces, the adhesion energy of spike protein was found to be (i) 0–1 mJ/m2 for hydrophilic inorganics (e.g., silica and glass) due to the lack of hydrogen bonding, (ii) 2–9 mJ/m2 for metals (e.g., alumina, SS, and copper) due to the variation of their binding capacity, and (iii) 6–11 mJ/m2 for hydrophobic polymers (e.g., medical masks, safety glass, and nitrile gloves) due to stronger hydrophobic interactions. The quantitative analysis of the nanomechanics of spike proteins will enable a protein–surface model database for SARS-CoV-2 to help generate effective preventive strategies to tackle the epidemic." @default.
• W3115668845 created "2021-01-05" @default.
• W3115668845 creator A5016393389 @default.
• W3115668845 creator A5028418565 @default.
• W3115668845 creator A5037717152 @default.
• W3115668845 creator A5053655509 @default.
• W3115668845 date "2020-12-18" @default.
• W3115668845 modified "2023-09-30" @default.
• W3115668845 title "A Nanomechanical Study on Deciphering the Stickiness of SARS-CoV-2 on Inanimate Surfaces" @default.
• W3115668845 cites W1979853118 @default.
• W3115668845 cites W1984335993 @default.
• W3115668845 cites W1991532978 @default.
• W3115668845 cites W1994716201 @default.
• W3115668845 cites W2008682560 @default.
• W3115668845 cites W2014020734 @default.
• W3115668845 cites W2038262006 @default.
• W3115668845 cites W2051454159 @default.
• W3115668845 cites W2069095831 @default.
• W3115668845 cites W2082566188 @default.
• W3115668845 cites W2106059993 @default.
• W3115668845 cites W2120746093 @default.
• W3115668845 cites W2141947008 @default.
• W3115668845 cites W2144446212 @default.
• W3115668845 cites W2150903279 @default.
• W3115668845 cites W2172096659 @default.
• W3115668845 cites W2270085459 @default.
• W3115668845 cites W2290724349 @default.
• W3115668845 cites W2321856359 @default.
• W3115668845 cites W2323957423 @default.
• W3115668845 cites W2429847166 @default.
• W3115668845 cites W2440411501 @default.
• W3115668845 cites W2516317998 @default.
• W3115668845 cites W2550166353 @default.
• W3115668845 cites W2564443324 @default.
• W3115668845 cites W2590117930 @default.
• W3115668845 cites W2642522075 @default.
• W3115668845 cites W2730915457 @default.
• W3115668845 cites W2747645752 @default.
• W3115668845 cites W2773082881 @default.
• W3115668845 cites W2773834250 @default.
• W3115668845 cites W2810687263 @default.
• W3115668845 cites W2899765786 @default.
• W3115668845 cites W2971543200 @default.
• W3115668845 cites W2996269228 @default.
• W3115668845 cites W2996957579 @default.
• W3115668845 cites W2999599394 @default.
• W3115668845 cites W3004893562 @default.
• W3115668845 cites W3005057892 @default.
• W3115668845 cites W3006645647 @default.
• W3115668845 cites W3007643904 @default.
• W3115668845 cites W3008827533 @default.
• W3115668845 cites W3009335299 @default.
• W3115668845 cites W3010131837 @default.
• W3115668845 cites W3010149441 @default.
• W3115668845 cites W3010223921 @default.
• W3115668845 cites W3010441732 @default.
• W3115668845 cites W3010604545 @default.
• W3115668845 cites W3011701533 @default.
• W3115668845 cites W3012099172 @default.
• W3115668845 cites W3012284084 @default.
• W3115668845 cites W3013800395 @default.
• W3115668845 cites W3014656992 @default.
• W3115668845 cites W3015185927 @default.
• W3115668845 cites W3015988827 @default.
• W3115668845 cites W3016872133 @default.
• W3115668845 doi "https://doi.org/10.1021/acsami.0c16800" @default.
• W3115668845 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7770894" @default.
• W3115668845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33337873" @default.
• W3115668845 hasPublicationYear "2020" @default.
• W3115668845 type Work @default.
• W3115668845 sameAs 3115668845 @default.
• W3115668845 citedByCount "24" @default.
• W3115668845 countsByYear W31156688452021 @default.
• W3115668845 countsByYear W31156688452022 @default.
• W3115668845 countsByYear W31156688452023 @default.
• W3115668845 crossrefType "journal-article" @default.
• W3115668845 hasAuthorship W3115668845A5016393389 @default.
• W3115668845 hasAuthorship W3115668845A5028418565 @default.
• W3115668845 hasAuthorship W3115668845A5037717152 @default.
• W3115668845 hasAuthorship W3115668845A5053655509 @default.
• W3115668845 hasBestOaLocation W31156688451 @default.
• W3115668845 hasConcept C112887158 @default.
• W3115668845 hasConcept C12554922 @default.
• W3115668845 hasConcept C127413603 @default.
• W3115668845 hasConcept C142724271 @default.
• W3115668845 hasConcept C150394285 @default.
• W3115668845 hasConcept C159985019 @default.
• W3115668845 hasConcept C162324750 @default.
• W3115668845 hasConcept C166950319 @default.
• W3115668845 hasConcept C171250308 @default.
• W3115668845 hasConcept C178790620 @default.
• W3115668845 hasConcept C185592680 @default.
• W3115668845 hasConcept C187736073 @default.
• W3115668845 hasConcept C192562407 @default.
• W3115668845 hasConcept C2777922577 @default.
• W3115668845 hasConcept C2779134260 @default.
• W3115668845 hasConcept C2781390188 @default.
• W3115668845 hasConcept C2909509916 @default.

• next