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• W3115730781 startingPage "16" @default.
• W3115730781 abstract "Gut microbiota (GM) is involved in the maintenance of physiological homeostasis, thus the alteration of its composition and functionality has been associated with many pathologies such as metabolic diseases, and could also be linked with the progressive degenerative process in aging. Nowadays, life expectancy is continuously rising, so the number of elder people and the consequent related pathologies demand new strategies to achieve healthy aging. Besides, actual lifestyle patterns make metabolic diseases a global epidemic with increasing trends, responsible for a large mortality and morbidity in adulthood and also compromising the health status of later stages of life. Metabolic diseases and aging share a profile of low-grade inflammation and innate immunity activation, which may have disturbances of GM composition as the leading mechanism. Thus, GM emerges as a therapeutic target with a double impact in the elderly, counteracting both aging itself and the frequent metabolic diseases in this population. This review summarizes the role and compositional changes of the GM in aging and its modulation through nutritional interventions and physical exercise as a strategy to counteract the aging process and the related metabolic diseases." @default.
• W3115730781 created "2021-01-05" @default.
• W3115730781 creator A5000152487 @default.
• W3115730781 creator A5001672453 @default.
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• W3115730781 creator A5044512290 @default.
• W3115730781 creator A5050242697 @default.
• W3115730781 creator A5084567869 @default.
• W3115730781 date "2020-12-23" @default.
• W3115730781 modified "2023-10-17" @default.
• W3115730781 title "Aging, Gut Microbiota and Metabolic Diseases: Management through Physical Exercise and Nutritional Interventions" @default.
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