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• W3115987866 endingPage "234" @default.
• W3115987866 startingPage "234" @default.
• W3115987866 abstract "The concept behind photodynamic therapy (PDT) is being successfully applied in different biomedical contexts such as cancer diseases, inactivation of microorganisms and, more recently, to improve wound healing and tissue regeneration. The effectiveness of PDT in skin treatments is associated with the role of reactive oxygen species (ROS) produced by a photosensitizer (PS), which acts as a “double agent”. The release of ROS must be high enough to prevent microbial growth and, simultaneously, to accelerate the immune system response by recruiting important regenerative agents to the wound site. The growing interest in this subject is reflected by the increasing number of studies concerning the optimization of relevant experimental parameters for wound healing via PDT, namely, light features, the structure and concentration of the PS, and the wound type and location. Considering the importance of developing PSs with suitable features for this emergent topic concerning skin wound healing, in this review, a special focus on the achievements attained for each PS class, namely, of the non-porphyrinoid type, is given." @default.
• W3115987866 created "2021-01-05" @default.
• W3115987866 creator A5032083897 @default.
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• W3115987866 creator A5086638370 @default.
• W3115987866 date "2020-12-28" @default.
• W3115987866 modified "2023-10-12" @default.
• W3115987866 title "An Insight into the Role of Non-Porphyrinoid Photosensitizers for Skin Wound Healing" @default.
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• W3115987866 doi "https://doi.org/10.3390/ijms22010234" @default.
• W3115987866 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7795024" @default.
• W3115987866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33379392" @default.

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