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• W3116069786 abstract "espanolLa anemia es la disminucion de la masa eritrocitaria normal de una persona, siendo insuficiente para un transporte optimo de oxigeno a los tejidos. El sindrome anemico es el conjunto de signos y sintomas derivados de este hecho y de los mecanismos compensadores segun la gravedad y duracion de la hipoxia. La poliglobulia se refiere a un aumento de la concentracion de hemoglobina y/o hematocrito en sangre periferica. El diagnostico de la causa especifica de poliglobulia es importante para el manejo adecuado del paciente. La anemia es el resultado de una o mas combinaciones de tres mecanismos basicos: perdida de sangre, disminucion de la produccion de hematies o aumento de la destruccion de hematies (hemolisis). Segun la clasificacion etiopatogenica, las anemias son regenerativas («perifericas») o arregenerativas («centrales»). El diagnostico de anemia en la practica clinica se realiza con la cifra de hemoglobina por debajo de los valores de referencia establecidos por la OMS y otros parametros eritrocitarios disponibles en un hemograma. Una historia clinica completa con anamnesis y exploracion fisica exhaustiva, junto con pruebas de laboratorio ademas del hemograma, como el frotis de sangre periferica, reticulocitos, prueba de Coombs y patron ferrico, entre otros, nos permitiran establecer el diagnostico diferencial inicial de la anemia basandonos en criterios morfologicos (microcitica, normocitica o macrocitica) y etiopatogenicos (regenerativas o arregenerativas). EnglishAnemia is a decrease in a person's normal red cell mass, making it insufficient for the optimal transportation of oxygen to tissues. Anemic syndrome is the set of signs and symptoms arising from this phenomenon and the compensatory mechanisms according to the severity and duration of the hypoxia. Polycythemia refers to an increase in the hemoglobin and/or hematocrit concentration in peripheral blood. The diagnosis of the specific cause of polycythemia is important for proper management of the patient. Anemia is the result of one or more combinations of three basic mechanisms: blood loss, a decrease in red blood cell production, or an increase in red blood cell destruction (hemolysis). According to the etiopathogenic classification, anemias are regenerative («peripheral») or non-regenerative («central»). A diagnosis of anemia is made in clinical practice with a hemoglobin figure below the reference values established by the WHO and other red blood cell parameters available on a complete blood count. A complete medical record with a comprehensive anamnesis and physical examination along with a complete blood count and laboratory tests, such as a peripheral blood and reticulocyte smear, Coombs test, and pattern of iron, among others, will allow us to establish an initial differential diagnosis of the anemia based on morphological (microcytic, normocytic, or macrocytic) and etiopathogenic (regenerative or non-regenerative) criteria." @default.
• W3116069786 created "2021-01-05" @default.
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• W3116069786 date "2020-11-01" @default.
• W3116069786 modified "2023-10-01" @default.
• W3116069786 title "Clasificación de las enfermedades del hematíe. Síndrome anémico y poliglobúlico. Concepto y clasificación" @default.
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• W3116069786 doi "https://doi.org/10.1016/j.med.2020.11.010" @default.
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