FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3116207877> ?p ?o ?g. }

• W3116207877 endingPage "129476" @default.
• W3116207877 startingPage "129476" @default.
• W3116207877 abstract "The toxicity of zinc oxide (ZnO NPs) and polystyrene nanoplastics (PS NaPs) has been tested in different animal models; however, knowledge about their impact on mice remains incipient. The aim of the current study is to evaluate the effects of these nanomaterials on Swiss mice after their individual exposure to a binary combination of them. The goal was to investigate whether short exposure (three days) to an environmentally relevant dose (14.6 ng/kg, i.p.) of these pollutants would have neurotoxic, biochemical and genotoxic effects on the modelss. Data in the current study have shown that the individual exposure of these animals has led to cognitive impairment based on the object recognition test, although the exposure experiment did not cause locomotor and anxiogenic or anxiolitic-like behavioral changes in them. This outcome was associated with increased nitric oxide levels, thiobarbituric acid reactive species, reduction in acetylcholinesterase activity and with the accumulation of nanomaterials in their brains. Results recorded for the assessed parameters did not differ between the control group and the groups exposed to the binary combination of pollutants. However, both the individual and the combined exposures caused erythrocyte DNA damages associated with hypercholesterolemic and hypertriglyceridemic conditions due to the presence of nanomaterials. Based on the results, the toxicological potential of ZnO NPs and PS NaPs in the models was confirmed and it encouraged further in-depth investigations about factors explaining the lack of additive or synergistic effect caused by the combined exposure to the assessed pollutants. • ZnO NPs and PS NaPs do not induce locomotor changes or anxiety-like behavior in mice. • Exposure to ZnO NPs and PS NaPs, in separate, induces cognitive impairment during the object recognition test. • Mice exposed to nanomaterials, in separate, show REDOX imbalance. • ZnO NPs and PS NaPs, in separate, suppresse the AChE activity. • DNA damage has been observed in mice exposed to nanomaterials (in separate, or in combination)." @default.
• W3116207877 created "2021-01-05" @default.
• W3116207877 creator A5014402430 @default.
• W3116207877 creator A5047614255 @default.
• W3116207877 creator A5053024837 @default.
• W3116207877 creator A5064910664 @default.
• W3116207877 creator A5068101403 @default.
• W3116207877 creator A5074086735 @default.
• W3116207877 creator A5074804419 @default.
• W3116207877 creator A5081537324 @default.
• W3116207877 date "2021-05-01" @default.
• W3116207877 modified "2023-10-01" @default.
• W3116207877 title "Toxicity of polystyrene nanoplastics and zinc oxide to mice" @default.
• W3116207877 cites W1111060747 @default.
• W3116207877 cites W1963673947 @default.
• W3116207877 cites W1963801462 @default.
• W3116207877 cites W1964102757 @default.
• W3116207877 cites W1970686359 @default.
• W3116207877 cites W1971048984 @default.
• W3116207877 cites W1983325630 @default.
• W3116207877 cites W1985278024 @default.
• W3116207877 cites W1991524161 @default.
• W3116207877 cites W1996074206 @default.
• W3116207877 cites W2002528172 @default.
• W3116207877 cites W2002760011 @default.
• W3116207877 cites W2003949705 @default.
• W3116207877 cites W2007458878 @default.
• W3116207877 cites W2013023382 @default.
• W3116207877 cites W2015954337 @default.
• W3116207877 cites W2028526056 @default.
• W3116207877 cites W2030554335 @default.
• W3116207877 cites W2031124263 @default.
• W3116207877 cites W2034485370 @default.
• W3116207877 cites W2037739053 @default.
• W3116207877 cites W2042133214 @default.
• W3116207877 cites W2043808271 @default.
• W3116207877 cites W2044246448 @default.
• W3116207877 cites W2046461866 @default.
• W3116207877 cites W2046922635 @default.
• W3116207877 cites W2058320183 @default.
• W3116207877 cites W2083042725 @default.
• W3116207877 cites W2083584399 @default.
• W3116207877 cites W2091043669 @default.
• W3116207877 cites W2092629964 @default.
• W3116207877 cites W2092733754 @default.
• W3116207877 cites W2130707940 @default.
• W3116207877 cites W2137260452 @default.
• W3116207877 cites W2146507509 @default.
• W3116207877 cites W2159580929 @default.
• W3116207877 cites W2162861984 @default.
• W3116207877 cites W2174307717 @default.
• W3116207877 cites W2182538746 @default.
• W3116207877 cites W2335534509 @default.
• W3116207877 cites W2412943775 @default.
• W3116207877 cites W2463532231 @default.
• W3116207877 cites W2518668171 @default.
• W3116207877 cites W2518797562 @default.
• W3116207877 cites W2534519274 @default.
• W3116207877 cites W2546520153 @default.
• W3116207877 cites W2560530909 @default.
• W3116207877 cites W2586426956 @default.
• W3116207877 cites W2587398111 @default.
• W3116207877 cites W2593966690 @default.
• W3116207877 cites W2616129231 @default.
• W3116207877 cites W2616822273 @default.
• W3116207877 cites W2742646427 @default.
• W3116207877 cites W2759842431 @default.
• W3116207877 cites W2768927119 @default.
• W3116207877 cites W2779935329 @default.
• W3116207877 cites W2790331078 @default.
• W3116207877 cites W2791561224 @default.
• W3116207877 cites W2793633494 @default.
• W3116207877 cites W2801174997 @default.
• W3116207877 cites W2804267945 @default.
• W3116207877 cites W2886270336 @default.
• W3116207877 cites W2888045560 @default.
• W3116207877 cites W2890392704 @default.
• W3116207877 cites W2895550034 @default.
• W3116207877 cites W2898156366 @default.
• W3116207877 cites W2904454786 @default.
• W3116207877 cites W2912641629 @default.
• W3116207877 cites W2918980157 @default.
• W3116207877 cites W2946093184 @default.
• W3116207877 cites W2946462015 @default.
• W3116207877 cites W2963223501 @default.
• W3116207877 cites W2964486340 @default.
• W3116207877 cites W2970182722 @default.
• W3116207877 cites W2971559802 @default.
• W3116207877 cites W2980436209 @default.
• W3116207877 cites W2985066496 @default.
• W3116207877 cites W2988310272 @default.
• W3116207877 cites W2990734047 @default.
• W3116207877 cites W2991485921 @default.
• W3116207877 cites W2992269203 @default.
• W3116207877 cites W2996300170 @default.
• W3116207877 cites W2999408469 @default.
• W3116207877 cites W3006228832 @default.
• W3116207877 cites W3007155206 @default.

• next