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- W3116295293 abstract "Titanium dioxide (TiO2) is used as a food additive (E171) and can be found in sauces, icings, and chewing gums, as well as in personal care products such as toothpaste and pharmaceutical tablets. Along with the ubiquitous presence of TiO2 and recent insights into its potentially hazardous properties, there are concerns about its application in commercially available products. Especially the nano-sized particle fraction (<100 nm) of TiO2 warrants a more detailed evaluation of potential adverse health effects after ingestion. A workshop organized by the Dutch Office for Risk Assessment and Research (BuRO) identified uncertainties and knowledge gaps regarding the gastrointestinal absorption of TiO2, its distribution, the potential for accumulation, and induction of adverse health effects such as inflammation, DNA damage, and tumor promotion. This review aims to identify and evaluate recent toxicological studies on food-grade TiO2 and nano-sized TiO2 in ex-vivo, in-vitro, and in-vivo experiments along the gastrointestinal route, and to postulate an Adverse Outcome Pathway (AOP) following ingestion. Additionally, this review summarizes recommendations and outcomes of the expert meeting held by the BuRO in 2018, in order to contribute to the hazard identification and risk assessment process of ingested TiO2." @default.
- W3116295293 created "2021-01-05" @default.
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- W3116295293 date "2020-12-28" @default.
- W3116295293 modified "2023-10-06" @default.
- W3116295293 title "Possible Adverse Effects of Food Additive E171 (Titanium Dioxide) Related to Particle Specific Human Toxicity, Including the Immune System" @default.
- W3116295293 cites W1425918444 @default.
- W3116295293 cites W1442521015 @default.
- W3116295293 cites W1555518634 @default.
- W3116295293 cites W1581596378 @default.
- W3116295293 cites W1816198559 @default.
- W3116295293 cites W1820616139 @default.
- W3116295293 cites W1949636578 @default.
- W3116295293 cites W1969040530 @default.
- W3116295293 cites W1969531715 @default.
- W3116295293 cites W1974829426 @default.
- W3116295293 cites W1983328643 @default.
- W3116295293 cites W1986246309 @default.
- W3116295293 cites W1987370223 @default.
- W3116295293 cites W1991344149 @default.
- W3116295293 cites W1995228853 @default.
- W3116295293 cites W1996087219 @default.
- W3116295293 cites W1996092132 @default.
- W3116295293 cites W2002003950 @default.
- W3116295293 cites W2009698835 @default.
- W3116295293 cites W2014329157 @default.
- W3116295293 cites W2015355247 @default.
- W3116295293 cites W2021622952 @default.
- W3116295293 cites W2025889178 @default.
- W3116295293 cites W2032921798 @default.
- W3116295293 cites W2034843771 @default.
- W3116295293 cites W2036690464 @default.
- W3116295293 cites W2046940432 @default.
- W3116295293 cites W2055870216 @default.
- W3116295293 cites W2065274698 @default.
- W3116295293 cites W2084153956 @default.
- W3116295293 cites W2084699949 @default.
- W3116295293 cites W2090107650 @default.
- W3116295293 cites W2090169681 @default.
- W3116295293 cites W2095802036 @default.
- W3116295293 cites W2099191918 @default.
- W3116295293 cites W2100168611 @default.
- W3116295293 cites W2100826681 @default.
- W3116295293 cites W2112080359 @default.
- W3116295293 cites W2113637303 @default.
- W3116295293 cites W2116479594 @default.
- W3116295293 cites W2122295866 @default.
- W3116295293 cites W2124072430 @default.
- W3116295293 cites W2124116255 @default.
- W3116295293 cites W2124688926 @default.
- W3116295293 cites W2125399349 @default.
- W3116295293 cites W2130448491 @default.
- W3116295293 cites W2131755453 @default.
- W3116295293 cites W2137094548 @default.
- W3116295293 cites W2147033192 @default.
- W3116295293 cites W2157896422 @default.
- W3116295293 cites W2169282855 @default.
- W3116295293 cites W2169703456 @default.
- W3116295293 cites W2233868012 @default.
- W3116295293 cites W2255766754 @default.
- W3116295293 cites W2276228554 @default.
- W3116295293 cites W2307660471 @default.
- W3116295293 cites W2342608211 @default.
- W3116295293 cites W2479685167 @default.
- W3116295293 cites W2483419783 @default.
- W3116295293 cites W2519779753 @default.
- W3116295293 cites W2522054313 @default.
- W3116295293 cites W2523024865 @default.
- W3116295293 cites W2525210719 @default.
- W3116295293 cites W2537405203 @default.
- W3116295293 cites W2541455124 @default.
- W3116295293 cites W2559814739 @default.
- W3116295293 cites W2577730091 @default.
- W3116295293 cites W2577859700 @default.
- W3116295293 cites W2584376131 @default.
- W3116295293 cites W2593452813 @default.
- W3116295293 cites W2604946521 @default.
- W3116295293 cites W2617813360 @default.
- W3116295293 cites W2622804241 @default.
- W3116295293 cites W2729424340 @default.
- W3116295293 cites W2738192122 @default.
- W3116295293 cites W2741055109 @default.
- W3116295293 cites W2747804636 @default.
- W3116295293 cites W2754680533 @default.