Matches in SemOpenAlex for { <https://semopenalex.org/work/W3116803970> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3116803970 endingPage "694" @default.
- W3116803970 startingPage "685" @default.
- W3116803970 abstract "The purpose of the study is to assess the effectiveness and toxicity of the treatment of prostate cancer (PCa) with combined radiation therapy (CRT), where high dose rate brachytherapy (HDR-BT) boost.
 Materials and methods: CRT was carried out in 98 patients of high-risk and extremely high-risk PCa. External part of treatment (conformal external radiation therapy) provided total dose 46-50 Gy with a single focal dose (SFD) 2 Gy to the prostate gland (PG), seminal vesicles and regional lymphatic zones. Two regimes of boost to the PG and seminal vesicles were used: in the first group – two fractions of 10 Gy (81 patients), in the second - 15 Gy (17 patients).
 Results: median follow-up equals: I group - 57.5 months, II group - 55.2. Three- and five-year survival without biochemical progression in group I - 75.4% and 69.0%, II group - 76.4% and 52.9%, respectively. Similar indicators regardless of the CRT regime in groups of different risk of relapse were equal: high risk - 84.6% and 75.9%, extremely high risk - 69.4% and 60.7%, respectively (p=0.05).
 There were no late radiation genitourinary and gastrointestinal complications of 4-5 degrees. The most significant variants of late disorders were the formation of urethra stricture (one patient of the I group) and stenosis of the rectum (one patient of the II group). Late genitourinary radiation toxicity (L-GURT) was mainly represented by changes that can be characterized as 1 degree (RTOG/CTCAE): I group - from 40.6% to 53.2%, II - 18.8% to 35.3%.
 Conclusions: the studied CRT regimes showed perfectly acceptable survival rates with no signs of biochemical progression and radiation toxicity during the five-year period of follow-up." @default.
- W3116803970 created "2021-01-05" @default.
- W3116803970 creator A5003040248 @default.
- W3116803970 creator A5007566889 @default.
- W3116803970 creator A5019771936 @default.
- W3116803970 creator A5022499644 @default.
- W3116803970 creator A5025745316 @default.
- W3116803970 creator A5040127100 @default.
- W3116803970 creator A5047940690 @default.
- W3116803970 creator A5062843359 @default.
- W3116803970 creator A5072343907 @default.
- W3116803970 date "2020-12-30" @default.
- W3116803970 modified "2023-09-27" @default.
- W3116803970 title "Five-year results of combined radiation therapy for high-risk prostate cancer" @default.
- W3116803970 cites W1965408806 @default.
- W3116803970 cites W2007300980 @default.
- W3116803970 cites W2015114518 @default.
- W3116803970 cites W2026641917 @default.
- W3116803970 cites W2037565714 @default.
- W3116803970 cites W2043945205 @default.
- W3116803970 cites W2047608066 @default.
- W3116803970 cites W2062313368 @default.
- W3116803970 cites W2063266750 @default.
- W3116803970 cites W2093867637 @default.
- W3116803970 cites W2156516389 @default.
- W3116803970 cites W2163954169 @default.
- W3116803970 cites W2498076434 @default.
- W3116803970 cites W2553678345 @default.
- W3116803970 cites W2758140423 @default.
- W3116803970 cites W2772705486 @default.
- W3116803970 cites W2789775641 @default.
- W3116803970 cites W2806525014 @default.
- W3116803970 cites W2895262488 @default.
- W3116803970 cites W2900778010 @default.
- W3116803970 cites W2947745091 @default.
- W3116803970 cites W2979496622 @default.
- W3116803970 cites W49263098 @default.
- W3116803970 doi "https://doi.org/10.37469/0507-3758-2020-66-6-685-694" @default.
- W3116803970 hasPublicationYear "2020" @default.
- W3116803970 type Work @default.
- W3116803970 sameAs 3116803970 @default.
- W3116803970 citedByCount "1" @default.
- W3116803970 countsByYear W31168039702021 @default.
- W3116803970 crossrefType "journal-article" @default.
- W3116803970 hasAuthorship W3116803970A5003040248 @default.
- W3116803970 hasAuthorship W3116803970A5007566889 @default.
- W3116803970 hasAuthorship W3116803970A5019771936 @default.
- W3116803970 hasAuthorship W3116803970A5022499644 @default.
- W3116803970 hasAuthorship W3116803970A5025745316 @default.
- W3116803970 hasAuthorship W3116803970A5040127100 @default.
- W3116803970 hasAuthorship W3116803970A5047940690 @default.
- W3116803970 hasAuthorship W3116803970A5062843359 @default.
- W3116803970 hasAuthorship W3116803970A5072343907 @default.
- W3116803970 hasBestOaLocation W31168039701 @default.
- W3116803970 hasConcept C121608353 @default.
- W3116803970 hasConcept C126322002 @default.
- W3116803970 hasConcept C126894567 @default.
- W3116803970 hasConcept C133507102 @default.
- W3116803970 hasConcept C2776235491 @default.
- W3116803970 hasConcept C2777416452 @default.
- W3116803970 hasConcept C2780192828 @default.
- W3116803970 hasConcept C2781074409 @default.
- W3116803970 hasConcept C2989005 @default.
- W3116803970 hasConcept C509974204 @default.
- W3116803970 hasConcept C71924100 @default.
- W3116803970 hasConceptScore W3116803970C121608353 @default.
- W3116803970 hasConceptScore W3116803970C126322002 @default.
- W3116803970 hasConceptScore W3116803970C126894567 @default.
- W3116803970 hasConceptScore W3116803970C133507102 @default.
- W3116803970 hasConceptScore W3116803970C2776235491 @default.
- W3116803970 hasConceptScore W3116803970C2777416452 @default.
- W3116803970 hasConceptScore W3116803970C2780192828 @default.
- W3116803970 hasConceptScore W3116803970C2781074409 @default.
- W3116803970 hasConceptScore W3116803970C2989005 @default.
- W3116803970 hasConceptScore W3116803970C509974204 @default.
- W3116803970 hasConceptScore W3116803970C71924100 @default.
- W3116803970 hasIssue "6" @default.
- W3116803970 hasLocation W31168039701 @default.
- W3116803970 hasOpenAccess W3116803970 @default.
- W3116803970 hasPrimaryLocation W31168039701 @default.
- W3116803970 hasRelatedWork W1544952821 @default.
- W3116803970 hasRelatedWork W1952411274 @default.
- W3116803970 hasRelatedWork W2023503398 @default.
- W3116803970 hasRelatedWork W2063508960 @default.
- W3116803970 hasRelatedWork W2085529113 @default.
- W3116803970 hasRelatedWork W2095924422 @default.
- W3116803970 hasRelatedWork W2123819582 @default.
- W3116803970 hasRelatedWork W2139928071 @default.
- W3116803970 hasRelatedWork W2143699516 @default.
- W3116803970 hasRelatedWork W2534674868 @default.
- W3116803970 hasVolume "66" @default.
- W3116803970 isParatext "false" @default.
- W3116803970 isRetracted "false" @default.
- W3116803970 magId "3116803970" @default.
- W3116803970 workType "article" @default.