FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3116969589> ?p ?o ?g. }

• W3116969589 abstract "Introduction: Cryopreserved arterial allografts have remained an option in patients requiring distal revascularization or associated with vascular infection, in the absence of a valid autogenous saphenous vein. The objective of this study is to describe the different clinical, anatomopathological, and immunological findings related to vascular transplant rejection. Methods: In a prospective trial, 35 patients who underwent cryopreserved allogeneic arterial bypass were studied, including demographics and conduit patency. Anti-HLA antibody production was stablished prior to the surgery, 7 days, 1, 3 months, and every 3 months since. Clinical and ultrasound evaluation was added after the first month. Donor HLA-typing was retrieved whenever available, allowing for the characterization and quantification of donor specific antibodies. Cytotoxic crossmatch test was also performed. A second group of patients with allograft degenerations registered during the follow up period was studied. In this group, exclusively for aneurysm description and histopathological analysis, they were included those degenerated vascular transplants from the original series, but also those implanted prior to the beginning of the study and degraded during follow up. Results: All patients studied displayed an increase in anti-HLA antibodies one month after the intervention, regarding bypass patency. In total, 14 patients fulfilled requirements for the study of donor specific antibodies, equally showing IgG production detectable one month after surgery. The presence of complement-fixing antibodies was also confirmed. Antibody levels were not related to graft degeneration. No specific immune markers able to predict aneurysmal development and evolution were found. From the original group, 3 patients suffered aneurysmal degeneration during follow up, together with 9 bypasses previously implanted. Average time until the first degeneration was 33 ± 19.7 months, with 30.6 ± 17.7 and 54.5 ± 2.5 months for a second and third degeneration, when occurring. Therefore, subsequent vascular transplants frequently augmented the time for new degenerations, despite increasing sensibilization. Samples from eight degenerated allografts were available for analysis, unexpectedly showing inflammatory infiltrate in only four cases and immune complex deposition in 7. Conclusions: Immune response against vascular transplants was confirmed in all cases, but chronic rejection did not necessarily provoke bypass degradation or reduced the time for new aneurysms to develop in subsequent allografts." @default.
• W3116969589 created "2021-01-05" @default.
• W3116969589 creator A5016615538 @default.
• W3116969589 creator A5029133420 @default.
• W3116969589 creator A5053777311 @default.
• W3116969589 creator A5059321141 @default.
• W3116969589 creator A5076951538 @default.
• W3116969589 creator A5077003817 @default.
• W3116969589 creator A5078117769 @default.
• W3116969589 creator A5079212007 @default.
• W3116969589 date "2020-12-22" @default.
• W3116969589 modified "2023-09-30" @default.
• W3116969589 title "Immunological Aspects Involved in the Degeneration of Cryopreserved Arterial Allografts" @default.
• W3116969589 cites W114401764 @default.
• W3116969589 cites W1581446430 @default.
• W3116969589 cites W1963613827 @default.
• W3116969589 cites W1967873427 @default.
• W3116969589 cites W1970716868 @default.
• W3116969589 cites W1975877059 @default.
• W3116969589 cites W2000705732 @default.
• W3116969589 cites W2001030051 @default.
• W3116969589 cites W2011391050 @default.
• W3116969589 cites W2017121844 @default.
• W3116969589 cites W2022720783 @default.
• W3116969589 cites W2037885440 @default.
• W3116969589 cites W2038257692 @default.
• W3116969589 cites W2050356155 @default.
• W3116969589 cites W2053494683 @default.
• W3116969589 cites W2053975524 @default.
• W3116969589 cites W2055541728 @default.
• W3116969589 cites W2079538530 @default.
• W3116969589 cites W2079573443 @default.
• W3116969589 cites W2087380451 @default.
• W3116969589 cites W2091389334 @default.
• W3116969589 cites W2092802650 @default.
• W3116969589 cites W2110360170 @default.
• W3116969589 cites W2111046650 @default.
• W3116969589 cites W2124221116 @default.
• W3116969589 cites W2142989413 @default.
• W3116969589 cites W2147356161 @default.
• W3116969589 cites W2157360387 @default.
• W3116969589 cites W2165115889 @default.
• W3116969589 cites W2168413430 @default.
• W3116969589 cites W2202298248 @default.
• W3116969589 cites W2284432111 @default.
• W3116969589 cites W2766042479 @default.
• W3116969589 cites W2770065689 @default.
• W3116969589 cites W2946028088 @default.
• W3116969589 cites W2963895723 @default.
• W3116969589 cites W4239238382 @default.
• W3116969589 cites W4239553742 @default.
• W3116969589 cites W792301347 @default.
• W3116969589 doi "https://doi.org/10.3389/fsurg.2020.616654" @default.
• W3116969589 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7783309" @default.
• W3116969589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33415125" @default.
• W3116969589 hasPublicationYear "2020" @default.
• W3116969589 type Work @default.
• W3116969589 sameAs 3116969589 @default.
• W3116969589 citedByCount "2" @default.
• W3116969589 countsByYear W31169695892023 @default.
• W3116969589 crossrefType "journal-article" @default.
• W3116969589 hasAuthorship W3116969589A5016615538 @default.
• W3116969589 hasAuthorship W3116969589A5029133420 @default.
• W3116969589 hasAuthorship W3116969589A5053777311 @default.
• W3116969589 hasAuthorship W3116969589A5059321141 @default.
• W3116969589 hasAuthorship W3116969589A5076951538 @default.
• W3116969589 hasAuthorship W3116969589A5077003817 @default.
• W3116969589 hasAuthorship W3116969589A5078117769 @default.
• W3116969589 hasAuthorship W3116969589A5079212007 @default.
• W3116969589 hasBestOaLocation W31169695891 @default.
• W3116969589 hasConcept C126322002 @default.
• W3116969589 hasConcept C141071460 @default.
• W3116969589 hasConcept C147483822 @default.
• W3116969589 hasConcept C159654299 @default.
• W3116969589 hasConcept C179933525 @default.
• W3116969589 hasConcept C188280979 @default.
• W3116969589 hasConcept C188816634 @default.
• W3116969589 hasConcept C196843134 @default.
• W3116969589 hasConcept C203014093 @default.
• W3116969589 hasConcept C2779464278 @default.
• W3116969589 hasConcept C500558357 @default.
• W3116969589 hasConcept C71924100 @default.
• W3116969589 hasConcept C86803240 @default.
• W3116969589 hasConcept C95444343 @default.
• W3116969589 hasConceptScore W3116969589C126322002 @default.
• W3116969589 hasConceptScore W3116969589C141071460 @default.
• W3116969589 hasConceptScore W3116969589C147483822 @default.
• W3116969589 hasConceptScore W3116969589C159654299 @default.
• W3116969589 hasConceptScore W3116969589C179933525 @default.
• W3116969589 hasConceptScore W3116969589C188280979 @default.
• W3116969589 hasConceptScore W3116969589C188816634 @default.
• W3116969589 hasConceptScore W3116969589C196843134 @default.
• W3116969589 hasConceptScore W3116969589C203014093 @default.
• W3116969589 hasConceptScore W3116969589C2779464278 @default.
• W3116969589 hasConceptScore W3116969589C500558357 @default.
• W3116969589 hasConceptScore W3116969589C71924100 @default.
• W3116969589 hasConceptScore W3116969589C86803240 @default.
• W3116969589 hasConceptScore W3116969589C95444343 @default.
• W3116969589 hasLocation W31169695891 @default.
• W3116969589 hasLocation W31169695892 @default.

• next