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- W3116982016 abstract "In most organisms ranging from cyanobacteria to humans, the endogenous timekeeping system temporally coordinates the behavioral, physiological, and metabolic processes with a periodicity close to 24 h. The timing of these daily rhythms is orchestrated by the synchronized oscillations of both the central pacemaker in the brain and the peripheral clocks located across multiple organs and tissues. A growing body of evidence suggests that the central circadian clock and peripheral clocks residing in the metabolically active tissues are incredibly well coordinated to confer coherent metabolic homeostasis. The interplay between nutrient metabolism and circadian rhythms can occur at various levels supported by the molecular clock network, multiple systemic mechanisms, and the neuroendocrine signaling pathways. While studies suggest the reciprocal regulation between circadian clock and metabolism, it is important to understand the precise mechanisms and the underlying pathways involved in the cross-talk among circadian oscillators and diverse metabolic networks. In addition to the internal synchronization of the metabolic rhythms, feeding time is considered as a potential external synchronization cue that fine tunes the timing of the circadian rhythms in metabolic peripheral clocks. A deeper understanding of how the timing of food intake and the diet composition drive the tissue-specific metabolic rhythms across the body is concomitantly important to develop novel therapeutic strategies for the metabolic disorders arising from circadian misalignment. This review summarizes the recent advancements in the circadian clock regulation of nutrient metabolism and discusses the current understanding of the metabolic feedback signals that link energy metabolism with the circadian clock." @default.
- W3116982016 created "2021-01-05" @default.
- W3116982016 creator A5065034864 @default.
- W3116982016 creator A5088667776 @default.
- W3116982016 date "2020-12-20" @default.
- W3116982016 modified "2023-10-16" @default.
- W3116982016 title "Only time will tell: the interplay between circadian clock and metabolism" @default.
- W3116982016 cites W146497533 @default.
- W3116982016 cites W1493050395 @default.
- W3116982016 cites W1529337805 @default.
- W3116982016 cites W1573412279 @default.
- W3116982016 cites W172331836 @default.
- W3116982016 cites W1779099806 @default.
- W3116982016 cites W1849188019 @default.
- W3116982016 cites W1853965878 @default.
- W3116982016 cites W1860625100 @default.
- W3116982016 cites W1946383112 @default.
- W3116982016 cites W1964634897 @default.
- W3116982016 cites W1965036088 @default.
- W3116982016 cites W1965546595 @default.
- W3116982016 cites W1966782228 @default.
- W3116982016 cites W1967142993 @default.
- W3116982016 cites W1967705197 @default.
- W3116982016 cites W1968076525 @default.
- W3116982016 cites W1968890500 @default.
- W3116982016 cites W1970084707 @default.
- W3116982016 cites W1971129732 @default.
- W3116982016 cites W1972140586 @default.
- W3116982016 cites W1973788573 @default.
- W3116982016 cites W1974219409 @default.
- W3116982016 cites W1974961331 @default.
- W3116982016 cites W1981265742 @default.
- W3116982016 cites W1981307611 @default.
- W3116982016 cites W1982920286 @default.
- W3116982016 cites W1984614962 @default.
- W3116982016 cites W1986209395 @default.
- W3116982016 cites W1987546711 @default.
- W3116982016 cites W1992493108 @default.
- W3116982016 cites W1992494470 @default.
- W3116982016 cites W1992749367 @default.
- W3116982016 cites W1994994441 @default.
- W3116982016 cites W1995104883 @default.
- W3116982016 cites W1997151200 @default.
- W3116982016 cites W1999429145 @default.
- W3116982016 cites W2001341743 @default.
- W3116982016 cites W2001618020 @default.
- W3116982016 cites W2004849589 @default.
- W3116982016 cites W2005166222 @default.
- W3116982016 cites W2005290542 @default.
- W3116982016 cites W2007299852 @default.
- W3116982016 cites W2014422314 @default.
- W3116982016 cites W2017193595 @default.
- W3116982016 cites W2017275974 @default.
- W3116982016 cites W2018021093 @default.
- W3116982016 cites W2019966996 @default.
- W3116982016 cites W2020898077 @default.
- W3116982016 cites W2021712795 @default.
- W3116982016 cites W2022267544 @default.
- W3116982016 cites W2022838347 @default.
- W3116982016 cites W2023286290 @default.
- W3116982016 cites W2023325911 @default.
- W3116982016 cites W2025018502 @default.
- W3116982016 cites W2025885587 @default.
- W3116982016 cites W2026930722 @default.
- W3116982016 cites W2027410128 @default.
- W3116982016 cites W2028181099 @default.
- W3116982016 cites W2028867134 @default.
- W3116982016 cites W2029818029 @default.
- W3116982016 cites W2031923163 @default.
- W3116982016 cites W2039196160 @default.
- W3116982016 cites W2040617029 @default.
- W3116982016 cites W2041300728 @default.
- W3116982016 cites W2042500733 @default.
- W3116982016 cites W2043195072 @default.
- W3116982016 cites W2043699343 @default.
- W3116982016 cites W2043808419 @default.
- W3116982016 cites W2044267389 @default.
- W3116982016 cites W2044458189 @default.
- W3116982016 cites W2044788178 @default.
- W3116982016 cites W2045675860 @default.
- W3116982016 cites W2045764832 @default.
- W3116982016 cites W2047545412 @default.
- W3116982016 cites W2047799635 @default.
- W3116982016 cites W2047902467 @default.
- W3116982016 cites W2050893944 @default.
- W3116982016 cites W2052267173 @default.
- W3116982016 cites W2052720016 @default.
- W3116982016 cites W2053414344 @default.
- W3116982016 cites W2054895739 @default.
- W3116982016 cites W2056265088 @default.
- W3116982016 cites W2057080091 @default.
- W3116982016 cites W2059196391 @default.
- W3116982016 cites W2064348721 @default.
- W3116982016 cites W2065119655 @default.
- W3116982016 cites W2065793682 @default.
- W3116982016 cites W2069742753 @default.
- W3116982016 cites W2070506262 @default.
- W3116982016 cites W2073036589 @default.