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• W3117090739 endingPage "364" @default.
• W3117090739 startingPage "358" @default.
• W3117090739 abstract "The switchable synthesis of 3-non, 3-mono, 3,3′-disubstituted 3,4-dihydroquinolin-2(1H)-ones was developed through a redox-neutral hydride-transfer/N-dealkylation/N-acylation strategy from o-aminobenzaldehyde with 4-hydroxycoumarin, and Meldrum’s acid, respectively. The unprecedented strategy for the synthesis of 3,3′-highly functionalized 3,4-dihydroquinolin-2(1H)-one has been realized with the in situ utilization of the released HCHO via the o-QM involved Michael addition. In addition, the synthetic utility of this protocol has been well illustrated via concise synthesis of CYP11B2 inhibitor." @default.
• W3117090739 created "2021-01-05" @default.
• W3117090739 creator A5003672136 @default.
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• W3117090739 creator A5072167166 @default.
• W3117090739 creator A5086664647 @default.
• W3117090739 date "2020-12-23" @default.
• W3117090739 modified "2023-10-18" @default.
• W3117090739 title "Redox-Triggered Switchable Synthesis of 3,4-Dihydroquinolin-2(1<i>H</i>)-one Derivatives via Hydride Transfer/<i>N</i>-Dealkylation/<i>N</i>-Acylation" @default.
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• W3117090739 doi "https://doi.org/10.1021/acs.orglett.0c03863" @default.
• W3117090739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33355465" @default.
• W3117090739 hasPublicationYear "2020" @default.
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