Matches in SemOpenAlex for { <https://semopenalex.org/work/W3117104199> ?p ?o ?g. }
- W3117104199 endingPage "283" @default.
- W3117104199 startingPage "275" @default.
- W3117104199 abstract "Identification of prognostic factors for perivascular wall tumours (PWTs) is desirable to accurately predict prognosis and guide treatment. 100 and two dogs with surgically excised PWTs without distant metastasis were retrospectively enrolled in this multi-institutional study, and the impact of pre-treatment leukocyte parameters, clinical and histopathological variables on local recurrence (LR) and overall-survival time (OST) were evaluated. Increasing values of white blood cell count (WBCC), neutrophil count (NC) and neutrophil-to-lymphocyte ratio (NLR) were significantly correlated with the hazard of LR in univariate analysis. WBCC and NC remained prognostic when adjusted for margins, grade, tumour size, location and skin ulceration, but lost their significance when adjusted for mitotic index and necrosis, whilst NLR remained prognostic only when close margins where categorised as infiltrated. Castrated males had a higher hazard of LR than intact males in univariate analysis, but significance was lost in multivariate models. Ulcerated PWTs and those located on the distal extremities had a higher hazard of LR both in univariate and multivariate analysis. Histological grade, necrosis, mitotic count, and infiltrated margins were all associated with LR both in univariate and multivariate analysis. Boxer breed, older age, ulceration, grade III, necrosis >50% and higher mitotic count were correlated with shorter OST, although breed and age lost their significance in multivariate analysis. Prognostication of surgically excised PWTs should be based on both clinical and histopathological variables. If validated in further studies, leukocyte counts and NLR may aid the clinician in identifying dogs at higher risk of LR before treatment." @default.
- W3117104199 created "2021-01-05" @default.
- W3117104199 creator A5010106603 @default.
- W3117104199 creator A5030527725 @default.
- W3117104199 creator A5039084397 @default.
- W3117104199 creator A5039398782 @default.
- W3117104199 creator A5040410901 @default.
- W3117104199 creator A5042267348 @default.
- W3117104199 creator A5042679651 @default.
- W3117104199 creator A5043687774 @default.
- W3117104199 creator A5047681762 @default.
- W3117104199 creator A5060364579 @default.
- W3117104199 creator A5063583733 @default.
- W3117104199 creator A5069730439 @default.
- W3117104199 creator A5075771599 @default.
- W3117104199 creator A5082978515 @default.
- W3117104199 creator A5084762307 @default.
- W3117104199 date "2021-01-08" @default.
- W3117104199 modified "2023-10-17" @default.
- W3117104199 title "Prognostic impact of clinical, haematological, and histopathological variables in 102 canine cutaneous perivascular wall tumours" @default.
- W3117104199 cites W1500590088 @default.
- W3117104199 cites W1701136927 @default.
- W3117104199 cites W1964737060 @default.
- W3117104199 cites W1965037168 @default.
- W3117104199 cites W1966762476 @default.
- W3117104199 cites W1971028719 @default.
- W3117104199 cites W1971211622 @default.
- W3117104199 cites W1982906652 @default.
- W3117104199 cites W1984480220 @default.
- W3117104199 cites W1990410488 @default.
- W3117104199 cites W2008706768 @default.
- W3117104199 cites W2018950208 @default.
- W3117104199 cites W2034791988 @default.
- W3117104199 cites W2066058844 @default.
- W3117104199 cites W2066621534 @default.
- W3117104199 cites W2095971807 @default.
- W3117104199 cites W2130373985 @default.
- W3117104199 cites W2130658267 @default.
- W3117104199 cites W2141344114 @default.
- W3117104199 cites W2142347762 @default.
- W3117104199 cites W2150080538 @default.
- W3117104199 cites W2150365029 @default.
- W3117104199 cites W2152818508 @default.
- W3117104199 cites W2169922341 @default.
- W3117104199 cites W2180665796 @default.
- W3117104199 cites W2210735273 @default.
- W3117104199 cites W2260686456 @default.
- W3117104199 cites W2521226266 @default.
- W3117104199 cites W2522353816 @default.
- W3117104199 cites W2530009604 @default.
- W3117104199 cites W2585010490 @default.
- W3117104199 cites W2592929337 @default.
- W3117104199 cites W2765082149 @default.
- W3117104199 cites W2890726344 @default.
- W3117104199 cites W2935318401 @default.
- W3117104199 cites W2940063750 @default.
- W3117104199 cites W2943501680 @default.
- W3117104199 cites W2946599421 @default.
- W3117104199 cites W2969398313 @default.
- W3117104199 cites W2989720300 @default.
- W3117104199 cites W2990418790 @default.
- W3117104199 cites W2990650944 @default.
- W3117104199 cites W4232811572 @default.
- W3117104199 cites W893134433 @default.
- W3117104199 doi "https://doi.org/10.1111/vco.12673" @default.
- W3117104199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33386693" @default.
- W3117104199 hasPublicationYear "2021" @default.
- W3117104199 type Work @default.
- W3117104199 sameAs 3117104199 @default.
- W3117104199 citedByCount "8" @default.
- W3117104199 countsByYear W31171041992021 @default.
- W3117104199 countsByYear W31171041992022 @default.
- W3117104199 countsByYear W31171041992023 @default.
- W3117104199 crossrefType "journal-article" @default.
- W3117104199 hasAuthorship W3117104199A5010106603 @default.
- W3117104199 hasAuthorship W3117104199A5030527725 @default.
- W3117104199 hasAuthorship W3117104199A5039084397 @default.
- W3117104199 hasAuthorship W3117104199A5039398782 @default.
- W3117104199 hasAuthorship W3117104199A5040410901 @default.
- W3117104199 hasAuthorship W3117104199A5042267348 @default.
- W3117104199 hasAuthorship W3117104199A5042679651 @default.
- W3117104199 hasAuthorship W3117104199A5043687774 @default.
- W3117104199 hasAuthorship W3117104199A5047681762 @default.
- W3117104199 hasAuthorship W3117104199A5060364579 @default.
- W3117104199 hasAuthorship W3117104199A5063583733 @default.
- W3117104199 hasAuthorship W3117104199A5069730439 @default.
- W3117104199 hasAuthorship W3117104199A5075771599 @default.
- W3117104199 hasAuthorship W3117104199A5082978515 @default.
- W3117104199 hasAuthorship W3117104199A5084762307 @default.
- W3117104199 hasBestOaLocation W31171041992 @default.
- W3117104199 hasConcept C105795698 @default.
- W3117104199 hasConcept C126322002 @default.
- W3117104199 hasConcept C142724271 @default.
- W3117104199 hasConcept C144301174 @default.
- W3117104199 hasConcept C161584116 @default.
- W3117104199 hasConcept C164465091 @default.
- W3117104199 hasConcept C199163554 @default.
- W3117104199 hasConcept C207103383 @default.