Matches in SemOpenAlex for { <https://semopenalex.org/work/W3117305225> ?p ?o ?g. }
- W3117305225 endingPage "62" @default.
- W3117305225 startingPage "52" @default.
- W3117305225 abstract "<b><i>Background:</i></b> Acute peptic ulcer bleeding is still a major reason for hospital admission. Especially the management of bleeding duodenal ulcers needs a structured therapeutic approach due to the higher morbidity and mortality compared to gastric ulcers. Patient with these bleeding ulcers are often in a high-risk situation, which requires multidisciplinary treatment. <b><i>Summary:</i></b> This review provides a structured approach to modern management of bleeding duodenal ulcers and elucidates therapeutic practice in high-risk situations. Initial management including pharmacologic therapy, risk stratification, endoscopy, surgery, and transcatheter arterial embolization are reviewed and their role in the management of bleeding duodenal ulcers is critically discussed. Additionally, a future perspective regarding prophylactic therapeutic approaches is outlined. <b><i>Key Messages:</i></b> Beside pharmacotherapeutic and endoscopic advances, bleeding management of high-risk duodenal ulcers is still a challenge. When bleeding persists or rebleeding occurs and the gold standard endoscopy fails, surgical and radiological procedures are indicated to manage ulcer bleeding. Surgical procedures are performed to control hemorrhage, but they are still associated with a higher morbidity and a longer hospital stay. In the meantime, transcatheter arterial embolization is recommended as an alternative to surgery and more often replaces surgery in the management of failed endoscopic hemostasis. Future studies are needed to improve risk stratification and therefore enable a better selection of high-risk ulcers and optimal treatment. Additionally, the promising approach of prophylactic embolization in high-risk duodenal ulcers has to be further investigated to reduce rebleeding and improve outcomes in these patients." @default.
- W3117305225 created "2021-01-05" @default.
- W3117305225 creator A5011294646 @default.
- W3117305225 creator A5090080616 @default.
- W3117305225 creator A5090675244 @default.
- W3117305225 date "2020-12-18" @default.
- W3117305225 modified "2023-10-16" @default.
- W3117305225 title "Bleeding Duodenal Ulcer: Strategies in High-Risk Ulcers" @default.
- W3117305225 cites W1508424780 @default.
- W3117305225 cites W1811517156 @default.
- W3117305225 cites W1825416676 @default.
- W3117305225 cites W1878051649 @default.
- W3117305225 cites W1902163979 @default.
- W3117305225 cites W1964314767 @default.
- W3117305225 cites W1966675765 @default.
- W3117305225 cites W1969878364 @default.
- W3117305225 cites W1982903554 @default.
- W3117305225 cites W1989313739 @default.
- W3117305225 cites W1996464494 @default.
- W3117305225 cites W1998803404 @default.
- W3117305225 cites W1999408248 @default.
- W3117305225 cites W2000551128 @default.
- W3117305225 cites W2008000582 @default.
- W3117305225 cites W2016146901 @default.
- W3117305225 cites W2016805852 @default.
- W3117305225 cites W2019794179 @default.
- W3117305225 cites W2022889473 @default.
- W3117305225 cites W2027154314 @default.
- W3117305225 cites W2038772968 @default.
- W3117305225 cites W2043387284 @default.
- W3117305225 cites W2043957826 @default.
- W3117305225 cites W2046301886 @default.
- W3117305225 cites W2048106278 @default.
- W3117305225 cites W2055354471 @default.
- W3117305225 cites W2057388746 @default.
- W3117305225 cites W2059057579 @default.
- W3117305225 cites W2060037724 @default.
- W3117305225 cites W2062765345 @default.
- W3117305225 cites W2065169828 @default.
- W3117305225 cites W2067264374 @default.
- W3117305225 cites W2072571958 @default.
- W3117305225 cites W2075175323 @default.
- W3117305225 cites W2075644299 @default.
- W3117305225 cites W2078201901 @default.
- W3117305225 cites W2080030569 @default.
- W3117305225 cites W2082630401 @default.
- W3117305225 cites W2087425008 @default.
- W3117305225 cites W2091313610 @default.
- W3117305225 cites W2097027767 @default.
- W3117305225 cites W2114614290 @default.
- W3117305225 cites W2116893095 @default.
- W3117305225 cites W2119216632 @default.
- W3117305225 cites W2121314908 @default.
- W3117305225 cites W2121674487 @default.
- W3117305225 cites W2131133423 @default.
- W3117305225 cites W2142903103 @default.
- W3117305225 cites W2146197194 @default.
- W3117305225 cites W2147000600 @default.
- W3117305225 cites W2147368252 @default.
- W3117305225 cites W2150824678 @default.
- W3117305225 cites W2160139130 @default.
- W3117305225 cites W2161740355 @default.
- W3117305225 cites W2166731097 @default.
- W3117305225 cites W2219775147 @default.
- W3117305225 cites W2315941418 @default.
- W3117305225 cites W2319239432 @default.
- W3117305225 cites W2328521740 @default.
- W3117305225 cites W235039075 @default.
- W3117305225 cites W2406497353 @default.
- W3117305225 cites W2410193904 @default.
- W3117305225 cites W2568089233 @default.
- W3117305225 cites W2586368255 @default.
- W3117305225 cites W2601519169 @default.
- W3117305225 cites W2727098592 @default.
- W3117305225 cites W2754959946 @default.
- W3117305225 cites W2766361435 @default.
- W3117305225 cites W2789924360 @default.
- W3117305225 cites W2799519829 @default.
- W3117305225 cites W2801182318 @default.
- W3117305225 cites W2803619919 @default.
- W3117305225 cites W2803962350 @default.
- W3117305225 cites W2912080396 @default.
- W3117305225 cites W2924668017 @default.
- W3117305225 cites W2934287672 @default.
- W3117305225 cites W2972680015 @default.
- W3117305225 cites W3014335647 @default.
- W3117305225 cites W3015066528 @default.
- W3117305225 cites W3016352148 @default.
- W3117305225 cites W3021411135 @default.
- W3117305225 cites W35095366 @default.
- W3117305225 cites W67781294 @default.
- W3117305225 doi "https://doi.org/10.1159/000513689" @default.
- W3117305225 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7923890" @default.
- W3117305225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33718484" @default.
- W3117305225 hasPublicationYear "2020" @default.
- W3117305225 type Work @default.
- W3117305225 sameAs 3117305225 @default.
- W3117305225 citedByCount "5" @default.