FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3117355893> ?p ?o ?g. }

• W3117355893 endingPage "722" @default.
• W3117355893 startingPage "718" @default.
• W3117355893 abstract "Infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can lead to coronavirus-induced disease 2019 (COVID-19). The gastrointestinal (GI) tract is now an appreciated portal of infection. SARS-CoV-2 enters host cells via angiotensin-converting enzyme-2 (ACE2) and the serine protease TMPRSS2. Eosinophilic gastrointestinal disorders (EGIDs) are inflammatory conditions caused by chronic type 2 (T2) inflammation. the effects of the T2 atopic inflammatory milieu on SARS-COV-2 viral entry gene expression in the GI tract is poorly understood. We analyzed tissue ACE2 and TMPRSS2 gene expression in pediatric eosinophilic esophagitis (EoE), eosinophilic gastritis (EG), and in normal adult esophagi using publicly available RNA-sequencing datasets. Similar to findings evaluating the airway, there was no difference in tissue ACE2/TMPRSS2 expression in EoE or EG when compared with control non-EoE/EG esophagus/stomach. ACE2 gene expression was significantly lower in esophagi from children with or without EoE and from adults with EoE as compared with normal adult esophagi. Type 2 immunity and pediatric age could be protective for infection by SARS-CoV-2 in the gastrointestinal tract because of decreased expression of ACE2." @default.
• W3117355893 created "2021-01-05" @default.
• W3117355893 creator A5011026120 @default.
• W3117355893 creator A5012642973 @default.
• W3117355893 creator A5016090753 @default.
• W3117355893 creator A5016425881 @default.
• W3117355893 creator A5021460379 @default.
• W3117355893 creator A5030477207 @default.
• W3117355893 creator A5030544000 @default.
• W3117355893 creator A5047742804 @default.
• W3117355893 creator A5055049011 @default.
• W3117355893 creator A5056639915 @default.
• W3117355893 creator A5062401038 @default.
• W3117355893 creator A5069050632 @default.
• W3117355893 creator A5074538839 @default.
• W3117355893 creator A5077168668 @default.
• W3117355893 creator A5078541910 @default.
• W3117355893 creator A5080535377 @default.
• W3117355893 creator A5083614666 @default.
• W3117355893 creator A5089210937 @default.
• W3117355893 creator A5091172284 @default.
• W3117355893 date "2020-12-23" @default.
• W3117355893 modified "2023-10-17" @default.
• W3117355893 title "Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders" @default.
• W3117355893 cites W2011298735 @default.
• W3117355893 cites W2146512944 @default.
• W3117355893 cites W2152329221 @default.
• W3117355893 cites W2157866223 @default.
• W3117355893 cites W2599652562 @default.
• W3117355893 cites W2936896628 @default.
• W3117355893 cites W2988614273 @default.
• W3117355893 cites W3008827533 @default.
• W3117355893 cites W3009912996 @default.
• W3117355893 cites W3012180666 @default.
• W3117355893 cites W3014288757 @default.
• W3117355893 cites W3015413289 @default.
• W3117355893 cites W3015494367 @default.
• W3117355893 cites W3019022818 @default.
• W3117355893 cites W3030727604 @default.
• W3117355893 cites W3032838347 @default.
• W3117355893 cites W3037081557 @default.
• W3117355893 doi "https://doi.org/10.1097/mpg.0000000000003032" @default.
• W3117355893 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8048378" @default.
• W3117355893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33394891" @default.
• W3117355893 hasPublicationYear "2020" @default.
• W3117355893 type Work @default.
• W3117355893 sameAs 3117355893 @default.
• W3117355893 citedByCount "12" @default.
• W3117355893 countsByYear W31173558932021 @default.
• W3117355893 countsByYear W31173558932022 @default.
• W3117355893 countsByYear W31173558932023 @default.
• W3117355893 crossrefType "journal-article" @default.
• W3117355893 hasAuthorship W3117355893A5011026120 @default.
• W3117355893 hasAuthorship W3117355893A5012642973 @default.
• W3117355893 hasAuthorship W3117355893A5016090753 @default.
• W3117355893 hasAuthorship W3117355893A5016425881 @default.
• W3117355893 hasAuthorship W3117355893A5021460379 @default.
• W3117355893 hasAuthorship W3117355893A5030477207 @default.
• W3117355893 hasAuthorship W3117355893A5030544000 @default.
• W3117355893 hasAuthorship W3117355893A5047742804 @default.
• W3117355893 hasAuthorship W3117355893A5055049011 @default.
• W3117355893 hasAuthorship W3117355893A5056639915 @default.
• W3117355893 hasAuthorship W3117355893A5062401038 @default.
• W3117355893 hasAuthorship W3117355893A5069050632 @default.
• W3117355893 hasAuthorship W3117355893A5074538839 @default.
• W3117355893 hasAuthorship W3117355893A5077168668 @default.
• W3117355893 hasAuthorship W3117355893A5078541910 @default.
• W3117355893 hasAuthorship W3117355893A5080535377 @default.
• W3117355893 hasAuthorship W3117355893A5083614666 @default.
• W3117355893 hasAuthorship W3117355893A5089210937 @default.
• W3117355893 hasAuthorship W3117355893A5091172284 @default.
• W3117355893 hasBestOaLocation W31173558931 @default.
• W3117355893 hasConcept C126322002 @default.
• W3117355893 hasConcept C142724271 @default.
• W3117355893 hasConcept C203014093 @default.
• W3117355893 hasConcept C2776914184 @default.
• W3117355893 hasConcept C2778260677 @default.
• W3117355893 hasConcept C2779134260 @default.
• W3117355893 hasConcept C2779644171 @default.
• W3117355893 hasConcept C2779758542 @default.
• W3117355893 hasConcept C2780512811 @default.
• W3117355893 hasConcept C2781065132 @default.
• W3117355893 hasConcept C534529494 @default.
• W3117355893 hasConcept C71924100 @default.
• W3117355893 hasConceptScore W3117355893C126322002 @default.
• W3117355893 hasConceptScore W3117355893C142724271 @default.
• W3117355893 hasConceptScore W3117355893C203014093 @default.
• W3117355893 hasConceptScore W3117355893C2776914184 @default.
• W3117355893 hasConceptScore W3117355893C2778260677 @default.
• W3117355893 hasConceptScore W3117355893C2779134260 @default.
• W3117355893 hasConceptScore W3117355893C2779644171 @default.
• W3117355893 hasConceptScore W3117355893C2779758542 @default.
• W3117355893 hasConceptScore W3117355893C2780512811 @default.
• W3117355893 hasConceptScore W3117355893C2781065132 @default.
• W3117355893 hasConceptScore W3117355893C534529494 @default.
• W3117355893 hasConceptScore W3117355893C71924100 @default.
• W3117355893 hasIssue "5" @default.
• W3117355893 hasLocation W31173558931 @default.

• next