FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3117385650> ?p ?o ?g. }

• W3117385650 endingPage "361" @default.
• W3117385650 startingPage "354" @default.
• W3117385650 abstract "Selective ophthalmic artery infusion chemotherapy has improved ocular outcomes in children with retinoblastoma. Our aim was to correlate quantitative tumor reduction and dichotomous therapeutic response with technical and adjunctive factors during selective ophthalmic artery infusion chemotherapy for retinoblastoma. An understanding of such factors may improve therapeutic efficacy.All patients with retinoblastoma treated by selective ophthalmic artery infusion chemotherapy at a single center during a 9-year period were reviewed. Only first-cycle treatments for previously untreated eyes were studied. Adjunctive factors (intra-arterial verapamil, intranasal oxymetazoline external carotid balloon occlusion) and technical factors (chemotherapy infusion time, fluoroscopy time) were documented by medical record review. Quantitative tumor reduction was determined by blinded comparison of retinal imaging acquired during examination under anesthesia before and 3-4 weeks after treatment. The dichotomous therapeutic response was classified according to quantitative tumor reduction as satisfactory (≥ 50%) or poor (<50%).Twenty-one eyes met the inclusion criteria. Patients ranged from 2 to 59 months of age. Adjuncts included intra-arterial verapamil in 15, intranasal oxymetazoline in 14, and external carotid balloon occlusion in 14. Quantitative tumor reduction ranged from 15% to 95%. Six showed poor dichotomous therapeutic response. A satisfactory dichotomous therapeutic response was correlated with intra-arterial verapamil (P = .03) in the aggregate cohort and in a subgroup undergoing treatment with single-agent melphalan at a dose of <5 mg (P = .02). In the latter, higher average quantitative tumor reduction correlated with intra-arterial verapamil (P < .01).Intra-arterial verapamil during selective ophthalmic artery infusion chemotherapy is correlated with an improved therapeutic response, particularly when treating with lower doses of single-agent melphalan." @default.
• W3117385650 created "2021-01-05" @default.
• W3117385650 creator A5007488752 @default.
• W3117385650 creator A5013359162 @default.
• W3117385650 creator A5034071001 @default.
• W3117385650 creator A5041966243 @default.
• W3117385650 creator A5049455893 @default.
• W3117385650 creator A5070358157 @default.
• W3117385650 creator A5072835260 @default.
• W3117385650 creator A5074724246 @default.
• W3117385650 date "2020-12-24" @default.
• W3117385650 modified "2023-10-10" @default.
• W3117385650 title "Correlation of Technical and Adjunctive Factors with Quantitative Tumor Reduction in Children Undergoing Selective Ophthalmic Artery Infusion Chemotherapy for Retinoblastoma" @default.
• W3117385650 cites W119080108 @default.
• W3117385650 cites W1572013196 @default.
• W3117385650 cites W1828326546 @default.
• W3117385650 cites W1925091978 @default.
• W3117385650 cites W1964973356 @default.
• W3117385650 cites W1981796703 @default.
• W3117385650 cites W1995509840 @default.
• W3117385650 cites W2014171231 @default.
• W3117385650 cites W2020218715 @default.
• W3117385650 cites W2027076258 @default.
• W3117385650 cites W2031510734 @default.
• W3117385650 cites W2036581844 @default.
• W3117385650 cites W2037859122 @default.
• W3117385650 cites W2050342311 @default.
• W3117385650 cites W2072425593 @default.
• W3117385650 cites W2075002404 @default.
• W3117385650 cites W2075500083 @default.
• W3117385650 cites W2148853356 @default.
• W3117385650 cites W2166823402 @default.
• W3117385650 cites W2172857005 @default.
• W3117385650 cites W2236957533 @default.
• W3117385650 cites W2286276337 @default.
• W3117385650 cites W2338840634 @default.
• W3117385650 cites W2402220659 @default.
• W3117385650 cites W2939933638 @default.
• W3117385650 cites W2951633557 @default.
• W3117385650 doi "https://doi.org/10.3174/ajnr.a6905" @default.
• W3117385650 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7872184" @default.
• W3117385650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33361377" @default.
• W3117385650 hasPublicationYear "2020" @default.
• W3117385650 type Work @default.
• W3117385650 sameAs 3117385650 @default.
• W3117385650 citedByCount "5" @default.
• W3117385650 countsByYear W31173856502022 @default.
• W3117385650 countsByYear W31173856502023 @default.
• W3117385650 crossrefType "journal-article" @default.
• W3117385650 hasAuthorship W3117385650A5007488752 @default.
• W3117385650 hasAuthorship W3117385650A5013359162 @default.
• W3117385650 hasAuthorship W3117385650A5034071001 @default.
• W3117385650 hasAuthorship W3117385650A5041966243 @default.
• W3117385650 hasAuthorship W3117385650A5049455893 @default.
• W3117385650 hasAuthorship W3117385650A5070358157 @default.
• W3117385650 hasAuthorship W3117385650A5072835260 @default.
• W3117385650 hasAuthorship W3117385650A5074724246 @default.
• W3117385650 hasBestOaLocation W31173856501 @default.
• W3117385650 hasConcept C102652120 @default.
• W3117385650 hasConcept C104317684 @default.
• W3117385650 hasConcept C126322002 @default.
• W3117385650 hasConcept C141071460 @default.
• W3117385650 hasConcept C158846371 @default.
• W3117385650 hasConcept C170493617 @default.
• W3117385650 hasConcept C185592680 @default.
• W3117385650 hasConcept C2776577112 @default.
• W3117385650 hasConcept C2776694085 @default.
• W3117385650 hasConcept C2777022698 @default.
• W3117385650 hasConcept C2780042274 @default.
• W3117385650 hasConcept C2780662894 @default.
• W3117385650 hasConcept C40465926 @default.
• W3117385650 hasConcept C42219234 @default.
• W3117385650 hasConcept C519063684 @default.
• W3117385650 hasConcept C55493867 @default.
• W3117385650 hasConcept C71924100 @default.
• W3117385650 hasConceptScore W3117385650C102652120 @default.
• W3117385650 hasConceptScore W3117385650C104317684 @default.
• W3117385650 hasConceptScore W3117385650C126322002 @default.
• W3117385650 hasConceptScore W3117385650C141071460 @default.
• W3117385650 hasConceptScore W3117385650C158846371 @default.
• W3117385650 hasConceptScore W3117385650C170493617 @default.
• W3117385650 hasConceptScore W3117385650C185592680 @default.
• W3117385650 hasConceptScore W3117385650C2776577112 @default.
• W3117385650 hasConceptScore W3117385650C2776694085 @default.
• W3117385650 hasConceptScore W3117385650C2777022698 @default.
• W3117385650 hasConceptScore W3117385650C2780042274 @default.
• W3117385650 hasConceptScore W3117385650C2780662894 @default.
• W3117385650 hasConceptScore W3117385650C40465926 @default.
• W3117385650 hasConceptScore W3117385650C42219234 @default.
• W3117385650 hasConceptScore W3117385650C519063684 @default.
• W3117385650 hasConceptScore W3117385650C55493867 @default.
• W3117385650 hasConceptScore W3117385650C71924100 @default.
• W3117385650 hasIssue "2" @default.
• W3117385650 hasLocation W31173856501 @default.
• W3117385650 hasLocation W31173856502 @default.
• W3117385650 hasLocation W31173856503 @default.
• W3117385650 hasOpenAccess W3117385650 @default.
• W3117385650 hasPrimaryLocation W31173856501 @default.

• next