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W3117443003 abstract "Significance GATA6 is a key regulator of sinus node (SAN) development. Loss of one Gata6 allele disrupts patterning and size of the SAN. GATA6 plays cell autonomous as well as non-cell autonomous functions in several cell types required for proper SAN development and function. Haploinsufficiency of Gata6 in mice leads to electrophysiological alterations and increases susceptibility to develop arrhythmias. GATA6 is critical for pacemaker cell differentiation and cardiac conduction." @default.
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W3117443003 date "2020-12-28" @default.
W3117443003 modified "2023-10-05" @default.
W3117443003 title "GATA6 is a regulator of sinus node development and heart rhythm" @default.
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W3117443003 doi "https://doi.org/10.1073/pnas.2007322118" @default.
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