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• W3118006869 abstract "• A simple sandwich method for coating preparation with predetermined thickness. • Support membrane entitled robust and uniform polymer coating on glass slide. • High selective composite coatings achieved via molecular imprinting technique. • Dyes detected visually and quantitatively by fluorescence on the coating. • Application of composite coatings for Direct-to-MS analysis was demonstrated. For a range of analytical applications, the microchips and slides used in sample preparation should be coated with functional (polymeric) materials. These coatings need to have controlled thickness, appropriate chemical/physical properties such as strong adhesion, and strength to resist external forces. Herein, we address these challenges using simple strategy to prepare polymer coatings by sandwiching a porous membrane soaked in vinyl monomer mixture between two glass slides, a bare slide and a slide immobilized with 3-(methacryloyloxy) propyltrimethoxysilane, and then thermal co-polymerization of monomers in the membrane and on the slide. The composite polymer coatings of different thickness (43∼227 μm) were formed on the slides by adjusting the thickness of support membrane (polytetrafluoroethylene). The composite polymer coated slides were successfully used for usual solid-phase microextraction, and for the visual detection of dyes and for fluorescent imaging and direct-to-MS detection without elution. The coatings have excellent stability, stiffness, and can be reused. They might be used in a variety of diagnostic and proteomics applications." @default.
• W3118006869 created "2021-01-05" @default.
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• W3118006869 date "2021-02-01" @default.
• W3118006869 modified "2023-10-18" @default.
• W3118006869 title "A novel sandwich method to prepare robust SPME polymer coating on glass slide with controllable thickness for direct analysis through fluorescence and MS imaging" @default.
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• W3118006869 doi "https://doi.org/10.1016/j.porgcoat.2020.106076" @default.
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