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- W3118049685 abstract "Abstract Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal malignancies of the gastrointestinal tract. GISTs can occur in the background of neurofibromatosis 1 (NF-1), where chemotherapeutic treatment is not optimal and surgical intervention is the only management option. In this case report, we present a case involving a 61-year-old gentleman with NF-1. The patient presented with acute blood loss anemia that was initially controlled with embolization of a hyper-vascular mass abutting the distal jejunum. The patient was taken to the operating room for excision of the mass. All macroscopic disease was excised and the pathology noted GISTs. Surgical decision making is not clearly delineated in the literature for GISTs in patients with NF-1, where targeted therapy is not a treatment option. Resection of all disease should be considered, since NF-1 associated GISTs generally do not have harbor mutations that can be targeted." @default.
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- W3118049685 date "2020-12-01" @default.
- W3118049685 modified "2023-09-23" @default.
- W3118049685 title "Case report: multiple gastrointestinal stroma tumors in the background of neurofibromatosis type 1" @default.
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- W3118049685 doi "https://doi.org/10.1093/jscr/rjaa516" @default.
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