FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3118374654> ?p ?o ?g. }

• W3118374654 endingPage "162" @default.
• W3118374654 startingPage "155" @default.
• W3118374654 abstract "Background/Aim: Arsenic trioxide (As₂O₃) is an environmental pollutant. However, the detailed mechanisms about As₂O₃-induced loss of endothelial integrity are unknown. This study aimed at investigating how As₂O₃ causes endothelial dysfunction and whether baicalin can reverse such dysfunction. Materials and Methods: Human umbilical vein endothelial cells (HUVECs) were used to examine As₂O₃-induced oxidative stress, and apoptosis. The influence of baicalin on As₂O₃-induced endothelial dysfunction were investigated. Results: The viability of HUVECs was inhibited by As₂O₃ and cells underwent apoptosis. As₂O₃ treatment increased NADPH oxidase activity, and elevated the level of reactive oxygen species (ROS). Formamidopyrimidine DNA-glycosylase- and endonuclease III-digestible adducts were accumulated. Baicalin reversed As₂O₃-induced apoptosis and As₂O₃-suppressed cell viability. Baicalin caused a decrease in NADPH oxidase activity, and re-balanced the ROS level. As₂O₃-induced formamidopyrimidine DNA-glycosylase- and endonuclease III-digestible adducts were down-regulated. Conclusion: Baicalin was found to have the potential capacity to protect endothelial cells from As₂O₃-induced cytotoxicity." @default.
• W3118374654 created "2021-01-18" @default.
• W3118374654 creator A5008264782 @default.
• W3118374654 creator A5033993454 @default.
• W3118374654 creator A5045950973 @default.
• W3118374654 creator A5060378168 @default.
• W3118374654 creator A5074784103 @default.
• W3118374654 creator A5086565881 @default.
• W3118374654 date "2021-01-01" @default.
• W3118374654 modified "2023-10-07" @default.
• W3118374654 title "Protective Effects of Baicalin on Arsenic Trioxide-induced Oxidative Damage and Apoptosis in Human Umbilical Vein Endothelial Cells" @default.
• W3118374654 cites W1058396857 @default.
• W3118374654 cites W1240531786 @default.
• W3118374654 cites W1431733044 @default.
• W3118374654 cites W1589890813 @default.
• W3118374654 cites W1980070066 @default.
• W3118374654 cites W1982884694 @default.
• W3118374654 cites W1984271811 @default.
• W3118374654 cites W1984680920 @default.
• W3118374654 cites W1984810473 @default.
• W3118374654 cites W1985810362 @default.
• W3118374654 cites W1995182877 @default.
• W3118374654 cites W2032284482 @default.
• W3118374654 cites W2045982598 @default.
• W3118374654 cites W2047294948 @default.
• W3118374654 cites W2058222699 @default.
• W3118374654 cites W2092557283 @default.
• W3118374654 cites W2093051812 @default.
• W3118374654 cites W2117817114 @default.
• W3118374654 cites W2137346704 @default.
• W3118374654 cites W2137525216 @default.
• W3118374654 cites W2143337784 @default.
• W3118374654 cites W2144388040 @default.
• W3118374654 cites W2145511954 @default.
• W3118374654 cites W2153686901 @default.
• W3118374654 cites W2161378722 @default.
• W3118374654 cites W2168739412 @default.
• W3118374654 cites W2171958520 @default.
• W3118374654 cites W2227072895 @default.
• W3118374654 cites W2336320822 @default.
• W3118374654 cites W2403470781 @default.
• W3118374654 cites W2507747027 @default.
• W3118374654 cites W2531437574 @default.
• W3118374654 cites W2625538399 @default.
• W3118374654 cites W2911440394 @default.
• W3118374654 cites W2943624499 @default.
• W3118374654 cites W2946527981 @default.
• W3118374654 cites W2947930584 @default.
• W3118374654 cites W2970593805 @default.
• W3118374654 cites W3012370914 @default.
• W3118374654 cites W3022413097 @default.
• W3118374654 doi "https://doi.org/10.21873/invivo.12243" @default.
• W3118374654 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7880760" @default.
• W3118374654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33402461" @default.
• W3118374654 hasPublicationYear "2021" @default.
• W3118374654 type Work @default.
• W3118374654 sameAs 3118374654 @default.
• W3118374654 citedByCount "10" @default.
• W3118374654 countsByYear W31183746542022 @default.
• W3118374654 countsByYear W31183746542023 @default.
• W3118374654 crossrefType "journal-article" @default.
• W3118374654 hasAuthorship W3118374654A5008264782 @default.
• W3118374654 hasAuthorship W3118374654A5033993454 @default.
• W3118374654 hasAuthorship W3118374654A5045950973 @default.
• W3118374654 hasAuthorship W3118374654A5060378168 @default.
• W3118374654 hasAuthorship W3118374654A5074784103 @default.
• W3118374654 hasAuthorship W3118374654A5086565881 @default.
• W3118374654 hasBestOaLocation W31183746541 @default.
• W3118374654 hasConcept C123012128 @default.
• W3118374654 hasConcept C134018914 @default.
• W3118374654 hasConcept C153911025 @default.
• W3118374654 hasConcept C179998833 @default.
• W3118374654 hasConcept C185592680 @default.
• W3118374654 hasConcept C190283241 @default.
• W3118374654 hasConcept C202751555 @default.
• W3118374654 hasConcept C2776151105 @default.
• W3118374654 hasConcept C2777411675 @default.
• W3118374654 hasConcept C2780113650 @default.
• W3118374654 hasConcept C2780386689 @default.
• W3118374654 hasConcept C2780972559 @default.
• W3118374654 hasConcept C43617362 @default.
• W3118374654 hasConcept C48349386 @default.
• W3118374654 hasConcept C53227056 @default.
• W3118374654 hasConcept C55493867 @default.
• W3118374654 hasConcept C86803240 @default.
• W3118374654 hasConceptScore W3118374654C123012128 @default.
• W3118374654 hasConceptScore W3118374654C134018914 @default.
• W3118374654 hasConceptScore W3118374654C153911025 @default.
• W3118374654 hasConceptScore W3118374654C179998833 @default.
• W3118374654 hasConceptScore W3118374654C185592680 @default.
• W3118374654 hasConceptScore W3118374654C190283241 @default.
• W3118374654 hasConceptScore W3118374654C202751555 @default.
• W3118374654 hasConceptScore W3118374654C2776151105 @default.
• W3118374654 hasConceptScore W3118374654C2777411675 @default.
• W3118374654 hasConceptScore W3118374654C2780113650 @default.
• W3118374654 hasConceptScore W3118374654C2780386689 @default.
• W3118374654 hasConceptScore W3118374654C2780972559 @default.
• W3118374654 hasConceptScore W3118374654C43617362 @default.

• next