FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3118431570> ?p ?o ?g. }

• W3118431570 endingPage "87" @default.
• W3118431570 startingPage "87" @default.
• W3118431570 abstract "The structures of the four N-linked glycans from the prototype chlorovirus PBCV-1 major capsid protein do not resemble any other glycans in the three domains of life. All known chloroviruses and antigenic variants (or mutants) share a unique conserved central glycan core consisting of five sugars, except for antigenic mutant virus P1L6, which has four of the five sugars. A combination of genetic and structural analyses indicates that the protein coded by PBCV-1 gene a111/114r, conserved in all chloroviruses, is a glycosyltransferase with three putative domains of approximately 300 amino acids each. Here, in addition to in silico sequence analysis and protein modeling, we measured the hydrolytic activity of protein A111/114R. The results suggest that domain 1 is a galactosyltransferase, domain 2 is a xylosyltransferase and domain 3 is a fucosyltransferase. Thus, A111/114R is the protein likely responsible for the attachment of three of the five conserved residues of the core region of this complex glycan, and, if biochemically corroborated, it would be the second three-domain protein coded by PBCV-1 that is involved in glycan synthesis. Importantly, these findings provide additional support that the chloroviruses do not use the canonical host endoplasmic reticulum–Golgi glycosylation pathway to glycosylate their glycoproteins; instead, they perform glycosylation independent of cellular organelles using virus-encoded enzymes." @default.
• W3118431570 created "2021-01-18" @default.
• W3118431570 creator A5006850722 @default.
• W3118431570 creator A5014775247 @default.
• W3118431570 creator A5077923163 @default.
• W3118431570 creator A5082174006 @default.
• W3118431570 creator A5087430065 @default.
• W3118431570 creator A5091674759 @default.
• W3118431570 date "2021-01-10" @default.
• W3118431570 modified "2023-10-17" @default.
• W3118431570 title "Chlorovirus PBCV-1 Multidomain Protein A111/114R Has Three Glycosyltransferase Functions Involved in the Synthesis of Atypical N-Glycans" @default.
• W3118431570 cites W1560642806 @default.
• W3118431570 cites W1803102843 @default.
• W3118431570 cites W1862479421 @default.
• W3118431570 cites W1912870130 @default.
• W3118431570 cites W1976055217 @default.
• W3118431570 cites W1993580205 @default.
• W3118431570 cites W2003129285 @default.
• W3118431570 cites W2004100214 @default.
• W3118431570 cites W2040556244 @default.
• W3118431570 cites W2059144219 @default.
• W3118431570 cites W2082667898 @default.
• W3118431570 cites W2086808934 @default.
• W3118431570 cites W2089601250 @default.
• W3118431570 cites W2100966009 @default.
• W3118431570 cites W2107134877 @default.
• W3118431570 cites W2128163894 @default.
• W3118431570 cites W2158714788 @default.
• W3118431570 cites W2179046140 @default.
• W3118431570 cites W2544661369 @default.
• W3118431570 cites W2592460359 @default.
• W3118431570 cites W2604098730 @default.
• W3118431570 cites W2608389566 @default.
• W3118431570 cites W2778390680 @default.
• W3118431570 cites W2803712803 @default.
• W3118431570 cites W2911464729 @default.
• W3118431570 cites W3010580300 @default.
• W3118431570 cites W3095956771 @default.
• W3118431570 cites W3171085489 @default.
• W3118431570 cites W4211188244 @default.
• W3118431570 doi "https://doi.org/10.3390/v13010087" @default.
• W3118431570 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7826918" @default.
• W3118431570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33435207" @default.
• W3118431570 hasPublicationYear "2021" @default.
• W3118431570 type Work @default.
• W3118431570 sameAs 3118431570 @default.
• W3118431570 citedByCount "7" @default.
• W3118431570 countsByYear W31184315702021 @default.
• W3118431570 countsByYear W31184315702022 @default.
• W3118431570 crossrefType "journal-article" @default.
• W3118431570 hasAuthorship W3118431570A5006850722 @default.
• W3118431570 hasAuthorship W3118431570A5014775247 @default.
• W3118431570 hasAuthorship W3118431570A5077923163 @default.
• W3118431570 hasAuthorship W3118431570A5082174006 @default.
• W3118431570 hasAuthorship W3118431570A5087430065 @default.
• W3118431570 hasAuthorship W3118431570A5091674759 @default.
• W3118431570 hasBestOaLocation W31184315701 @default.
• W3118431570 hasConcept C104317684 @default.
• W3118431570 hasConcept C108625454 @default.
• W3118431570 hasConcept C119062480 @default.
• W3118431570 hasConcept C143065580 @default.
• W3118431570 hasConcept C144292202 @default.
• W3118431570 hasConcept C158617107 @default.
• W3118431570 hasConcept C161019410 @default.
• W3118431570 hasConcept C167625842 @default.
• W3118431570 hasConcept C206212055 @default.
• W3118431570 hasConcept C2777313579 @default.
• W3118431570 hasConcept C2777762822 @default.
• W3118431570 hasConcept C45484198 @default.
• W3118431570 hasConcept C47701112 @default.
• W3118431570 hasConcept C55493867 @default.
• W3118431570 hasConcept C86803240 @default.
• W3118431570 hasConceptScore W3118431570C104317684 @default.
• W3118431570 hasConceptScore W3118431570C108625454 @default.
• W3118431570 hasConceptScore W3118431570C119062480 @default.
• W3118431570 hasConceptScore W3118431570C143065580 @default.
• W3118431570 hasConceptScore W3118431570C144292202 @default.
• W3118431570 hasConceptScore W3118431570C158617107 @default.
• W3118431570 hasConceptScore W3118431570C161019410 @default.
• W3118431570 hasConceptScore W3118431570C167625842 @default.
• W3118431570 hasConceptScore W3118431570C206212055 @default.
• W3118431570 hasConceptScore W3118431570C2777313579 @default.
• W3118431570 hasConceptScore W3118431570C2777762822 @default.
• W3118431570 hasConceptScore W3118431570C45484198 @default.
• W3118431570 hasConceptScore W3118431570C47701112 @default.
• W3118431570 hasConceptScore W3118431570C55493867 @default.
• W3118431570 hasConceptScore W3118431570C86803240 @default.
• W3118431570 hasFunder F4320306076 @default.
• W3118431570 hasIssue "1" @default.
• W3118431570 hasLocation W31184315701 @default.
• W3118431570 hasLocation W31184315702 @default.
• W3118431570 hasLocation W31184315703 @default.
• W3118431570 hasLocation W31184315704 @default.
• W3118431570 hasOpenAccess W3118431570 @default.
• W3118431570 hasPrimaryLocation W31184315701 @default.
• W3118431570 hasRelatedWork W2000410789 @default.
• W3118431570 hasRelatedWork W2043649067 @default.
• W3118431570 hasRelatedWork W2060105373 @default.

• next