FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3118441034> ?p ?o ?g. }

• W3118441034 abstract "Abstract Objective To systematically describe central (CNS) and peripheral (PNS) nervous system complications in hospitalized COVID-19 patients. Methods We conducted a prospective, consecutive, observational study of adult patients from a tertiary referral center with confirmed COVID-19. All patients were screened daily for neurological and neuropsychiatric symptoms during admission and discharge. Three-month follow-up data were collected using electronic health records. We classified complications as caused by SARS-CoV-2 neurotropism, immune-mediated or critical illness-related. Results From April to September 2020, we enrolled 61 consecutively admitted COVID-19 patients, 35 (57%) of whom required intensive care (ICU) management for respiratory failure. Forty-one CNS/PNS complications were identified in 28 of 61 (45.9%) patients and were more frequent in ICU compared to non-ICU patients. The most common CNS complication was encephalopathy ( n = 19, 31.1%), which was severe in 13 patients (GCS ≤ 12), including 8 with akinetic mutism. Length of ICU admission was independently associated with encephalopathy (OR = 1.22). Other CNS complications included ischemic stroke, a biopsy-proven acute necrotizing encephalitis, and transverse myelitis. The most common PNS complication was critical illness polyneuromyopathy (13.1%), with prolonged ICU stay as independent predictor (OR = 1.14). Treatment-related PNS complications included meralgia paresthetica. Of 41 complications in total, 3 were para/post-infectious, 34 were secondary to critical illness or other causes, and 4 remained unresolved. Cerebrospinal fluid was negative for SARS-CoV-2 RNA in all 5 patients investigated. Conclusion CNS and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral neurotropism were detected, but laboratory changes suggested autoimmune-mediated mechanisms." @default.
• W3118441034 created "2021-01-18" @default.
• W3118441034 creator A5001644102 @default.
• W3118441034 creator A5005569324 @default.
• W3118441034 creator A5008298299 @default.
• W3118441034 creator A5019468970 @default.
• W3118441034 creator A5022635248 @default.
• W3118441034 creator A5026668188 @default.
• W3118441034 creator A5027802520 @default.
• W3118441034 creator A5028623072 @default.
• W3118441034 creator A5037007499 @default.
• W3118441034 creator A5038083786 @default.
• W3118441034 creator A5039228105 @default.
• W3118441034 creator A5044624417 @default.
• W3118441034 creator A5053811577 @default.
• W3118441034 creator A5057311705 @default.
• W3118441034 creator A5059183931 @default.
• W3118441034 creator A5060295757 @default.
• W3118441034 creator A5066925484 @default.
• W3118441034 creator A5071046673 @default.
• W3118441034 creator A5072348236 @default.
• W3118441034 creator A5085169796 @default.
• W3118441034 creator A5090790093 @default.
• W3118441034 date "2021-01-13" @default.
• W3118441034 modified "2023-10-03" @default.
• W3118441034 title "Central and peripheral nervous system complications of COVID-19: a prospective tertiary center cohort with 3-month follow-up" @default.
• W3118441034 cites W1656822188 @default.
• W3118441034 cites W1870461993 @default.
• W3118441034 cites W1981368024 @default.
• W3118441034 cites W2149223457 @default.
• W3118441034 cites W2164481426 @default.
• W3118441034 cites W2169697627 @default.
• W3118441034 cites W2170443869 @default.
• W3118441034 cites W2302408199 @default.
• W3118441034 cites W2525045335 @default.
• W3118441034 cites W2599859498 @default.
• W3118441034 cites W2610376894 @default.
• W3118441034 cites W2610582798 @default.
• W3118441034 cites W3004476035 @default.
• W3118441034 cites W3005686380 @default.
• W3118441034 cites W3012421327 @default.
• W3118441034 cites W3013398803 @default.
• W3118441034 cites W3014310029 @default.
• W3118441034 cites W3015925195 @default.
• W3118441034 cites W3016127017 @default.
• W3118441034 cites W3031033561 @default.
• W3118441034 cites W3031237995 @default.
• W3118441034 cites W3032104273 @default.
• W3118441034 cites W3033833391 @default.
• W3118441034 cites W3034546965 @default.
• W3118441034 cites W3035063822 @default.
• W3118441034 cites W3035878353 @default.
• W3118441034 cites W3036527390 @default.
• W3118441034 cites W3037348448 @default.
• W3118441034 cites W3037539912 @default.
• W3118441034 cites W3040749370 @default.
• W3118441034 cites W3040794648 @default.
• W3118441034 cites W3041630129 @default.
• W3118441034 cites W3049257232 @default.
• W3118441034 cites W3080497013 @default.
• W3118441034 cites W3086751973 @default.
• W3118441034 cites W3088093906 @default.
• W3118441034 cites W3090344202 @default.
• W3118441034 cites W3091466380 @default.
• W3118441034 cites W3091658787 @default.
• W3118441034 cites W3092606736 @default.
• W3118441034 cites W4210575617 @default.
• W3118441034 doi "https://doi.org/10.1007/s00415-020-10380-x" @default.
• W3118441034 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7803470" @default.
• W3118441034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33438076" @default.
• W3118441034 hasPublicationYear "2021" @default.
• W3118441034 type Work @default.
• W3118441034 sameAs 3118441034 @default.
• W3118441034 citedByCount "55" @default.
• W3118441034 countsByYear W31184410342021 @default.
• W3118441034 countsByYear W31184410342022 @default.
• W3118441034 countsByYear W31184410342023 @default.
• W3118441034 crossrefType "journal-article" @default.
• W3118441034 hasAuthorship W3118441034A5001644102 @default.
• W3118441034 hasAuthorship W3118441034A5005569324 @default.
• W3118441034 hasAuthorship W3118441034A5008298299 @default.
• W3118441034 hasAuthorship W3118441034A5019468970 @default.
• W3118441034 hasAuthorship W3118441034A5022635248 @default.
• W3118441034 hasAuthorship W3118441034A5026668188 @default.
• W3118441034 hasAuthorship W3118441034A5027802520 @default.
• W3118441034 hasAuthorship W3118441034A5028623072 @default.
• W3118441034 hasAuthorship W3118441034A5037007499 @default.
• W3118441034 hasAuthorship W3118441034A5038083786 @default.
• W3118441034 hasAuthorship W3118441034A5039228105 @default.
• W3118441034 hasAuthorship W3118441034A5044624417 @default.
• W3118441034 hasAuthorship W3118441034A5053811577 @default.
• W3118441034 hasAuthorship W3118441034A5057311705 @default.
• W3118441034 hasAuthorship W3118441034A5059183931 @default.
• W3118441034 hasAuthorship W3118441034A5060295757 @default.
• W3118441034 hasAuthorship W3118441034A5066925484 @default.
• W3118441034 hasAuthorship W3118441034A5071046673 @default.
• W3118441034 hasAuthorship W3118441034A5072348236 @default.
• W3118441034 hasAuthorship W3118441034A5085169796 @default.
• W3118441034 hasAuthorship W3118441034A5090790093 @default.
• W3118441034 hasBestOaLocation W31184410341 @default.

• next