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- W3118553697 abstract "We explored the bioinspired o-quinone cofactor catalyzed aerobic primary amine dehydrogenation for a cascade olefination reaction with nine different methyl N-heteroarenes, including pyrimidines, pyrazines, pyridines, quinolines, quinoxolines, benzimidazoles, benzoxazoles, benzthiazoles, and triazines. An o-quinone catalyst phd (1,10-phenanthroline-5,6-dione) combined with a Brønsted acid catalyzed the reaction. N-Heteroaryl stilbenoids were synthesized in high yields and (E)-selectivities under mild conditions using oxygen (1 atm) as the sole oxidant without needing transition-metal salt, ligand, stoichiometric base, or oxidant." @default.
- W3118553697 created "2021-01-18" @default.
- W3118553697 creator A5034202353 @default.
- W3118553697 creator A5057508523 @default.
- W3118553697 date "2021-01-07" @default.
- W3118553697 modified "2023-10-16" @default.
- W3118553697 title "Deaminative Olefination of Methyl <i>N</i>-Heteroarenes by an Amine Oxidase Inspired Catalyst" @default.
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- W3118553697 doi "https://doi.org/10.1021/acs.orglett.0c04060" @default.
- W3118553697 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33410694" @default.
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