FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3118654820> ?p ?o ?g. }

• W3118654820 endingPage "168" @default.
• W3118654820 startingPage "163" @default.
• W3118654820 abstract "ABSTRACTIntroduction: Patients affected by Inborn Errors of Immunity (IEI) represent a potential group-at-risk in the current COVID-19 pandemic. Studies on large and small cohorts of IEI reported a huge variability clinical manifestations associated to SARS-Cov-2, ranging from asymptomatic, mild, moderate/severe to death. A great impulse to improve remote assistance programs and to switch to home-based treatment to reduce mobility and face to face contacts has been implemented.Areas covered: The authors completed a comprehensive review of the literature by searching the PubMed database for studies on large and small cohorts and case reports of IEI patients with COVID-19, with the aim to provide useful information for their clinical management during the COVID-19 pandemic.Expert opinion: Surprisingly, a low number of IEI patients affected by SARS-Cov-2 were reported with a risk to die for COVID-19 overlapping that of the general population. The low number might be explained by the choice of most physicians to inform early in the pandemic about safety measures, to switch most of the IEI patients to home therapy and to remote assistance. The guidelines issued by the scientific societies and periodically updated, represent the best tool for the clinical management of IEI patients.KEYWORDS: Inborn errors of immunity (IEI)SARS-CoV-2COVID-19immunoglobulin replacementconvalescent plasmaremote assistancehome-based treatmentguidelinesvirus escape mutants Article highlightsCOVID-19 in IEI patients does not appear to be significantly different from the general population with the exception of a younger age, and a longer length of SARS-Cov-2 positivity.Most patients with antibody production defects do not experience severe disease.Patients with predominantly T cell defects, and defects of innate immunity are under-represented in the reported cohorts preventing an assessment of any correlation with COVID-19 severity.Co-morbid conditions appear to be relative rare, but important in determining outcome.IEI patients with COVID-19 should be referred to their consultant specialists due to the high variability of COVID-19 presentation even within the same IEI condition.AcknowledgmentsWe thank all MD, nurses, and health personnel taking care of COVID-19 patients over the world.Declaration of interestThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.Reviewer disclosuresPeer reviewers on this manuscript have no relevant financial or other relationships to disclose.Ethical approvalThis article does not contain any studies with human participants or animals performed by any of the authors.Additional informationFundingThis paper was funded by Progetto Ateneo Sapienza, 2020." @default.
• W3118654820 created "2021-01-18" @default.
• W3118654820 creator A5016770644 @default.
• W3118654820 creator A5055544432 @default.
• W3118654820 creator A5061248177 @default.
• W3118654820 date "2021-01-15" @default.
• W3118654820 modified "2023-10-17" @default.
• W3118654820 title "Clinical management of patients with primary immunodeficiencies during the COVID-19 pandemic" @default.
• W3118654820 cites W2090132252 @default.
• W3118654820 cites W2409038037 @default.
• W3118654820 cites W2626908533 @default.
• W3118654820 cites W2774787224 @default.
• W3118654820 cites W2999868420 @default.
• W3118654820 cites W3005335417 @default.
• W3118654820 cites W3009885589 @default.
• W3118654820 cites W3011183720 @default.
• W3118654820 cites W3014007058 @default.
• W3118654820 cites W3016118615 @default.
• W3118654820 cites W3016319005 @default.
• W3118654820 cites W3016852213 @default.
• W3118654820 cites W3018910405 @default.
• W3118654820 cites W3027545596 @default.
• W3118654820 cites W3032394272 @default.
• W3118654820 cites W3033675174 @default.
• W3118654820 cites W3035867355 @default.
• W3118654820 cites W3038823489 @default.
• W3118654820 cites W3048909141 @default.
• W3118654820 cites W3087063072 @default.
• W3118654820 cites W3087074054 @default.
• W3118654820 cites W3087862874 @default.
• W3118654820 cites W3088256443 @default.
• W3118654820 cites W3093887953 @default.
• W3118654820 cites W3094870207 @default.
• W3118654820 cites W3102798166 @default.
• W3118654820 cites W3105698183 @default.
• W3118654820 doi "https://doi.org/10.1080/1744666x.2021.1873767" @default.
• W3118654820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33412960" @default.
• W3118654820 hasPublicationYear "2021" @default.
• W3118654820 type Work @default.
• W3118654820 sameAs 3118654820 @default.
• W3118654820 citedByCount "13" @default.
• W3118654820 countsByYear W31186548202021 @default.
• W3118654820 countsByYear W31186548202022 @default.
• W3118654820 countsByYear W31186548202023 @default.
• W3118654820 crossrefType "journal-article" @default.
• W3118654820 hasAuthorship W3118654820A5016770644 @default.
• W3118654820 hasAuthorship W3118654820A5055544432 @default.
• W3118654820 hasAuthorship W3118654820A5061248177 @default.
• W3118654820 hasBestOaLocation W31186548202 @default.
• W3118654820 hasConcept C126322002 @default.
• W3118654820 hasConcept C17744445 @default.
• W3118654820 hasConcept C177713679 @default.
• W3118654820 hasConcept C187212893 @default.
• W3118654820 hasConcept C199539241 @default.
• W3118654820 hasConcept C2777910003 @default.
• W3118654820 hasConcept C2779134260 @default.
• W3118654820 hasConcept C2779473830 @default.
• W3118654820 hasConcept C2908647359 @default.
• W3118654820 hasConcept C3007834351 @default.
• W3118654820 hasConcept C3008058167 @default.
• W3118654820 hasConcept C524204448 @default.
• W3118654820 hasConcept C71924100 @default.
• W3118654820 hasConcept C89623803 @default.
• W3118654820 hasConcept C99454951 @default.
• W3118654820 hasConceptScore W3118654820C126322002 @default.
• W3118654820 hasConceptScore W3118654820C17744445 @default.
• W3118654820 hasConceptScore W3118654820C177713679 @default.
• W3118654820 hasConceptScore W3118654820C187212893 @default.
• W3118654820 hasConceptScore W3118654820C199539241 @default.
• W3118654820 hasConceptScore W3118654820C2777910003 @default.
• W3118654820 hasConceptScore W3118654820C2779134260 @default.
• W3118654820 hasConceptScore W3118654820C2779473830 @default.
• W3118654820 hasConceptScore W3118654820C2908647359 @default.
• W3118654820 hasConceptScore W3118654820C3007834351 @default.
• W3118654820 hasConceptScore W3118654820C3008058167 @default.
• W3118654820 hasConceptScore W3118654820C524204448 @default.
• W3118654820 hasConceptScore W3118654820C71924100 @default.
• W3118654820 hasConceptScore W3118654820C89623803 @default.
• W3118654820 hasConceptScore W3118654820C99454951 @default.
• W3118654820 hasIssue "2" @default.
• W3118654820 hasLocation W31186548201 @default.
• W3118654820 hasLocation W31186548202 @default.
• W3118654820 hasOpenAccess W3118654820 @default.
• W3118654820 hasPrimaryLocation W31186548201 @default.
• W3118654820 hasRelatedWork W3017171836 @default.
• W3118654820 hasRelatedWork W3025176011 @default.
• W3118654820 hasRelatedWork W3027835066 @default.
• W3118654820 hasRelatedWork W3032320397 @default.
• W3118654820 hasRelatedWork W3033635008 @default.
• W3118654820 hasRelatedWork W3119540162 @default.
• W3118654820 hasRelatedWork W3127941442 @default.
• W3118654820 hasRelatedWork W4280491013 @default.
• W3118654820 hasRelatedWork W4308017287 @default.
• W3118654820 hasRelatedWork W3107152225 @default.
• W3118654820 hasVolume "17" @default.
• W3118654820 isParatext "false" @default.
• W3118654820 isRetracted "false" @default.
• W3118654820 magId "3118654820" @default.

• next