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- W3118679080 abstract "We thank the correspondent for the thoughtful consideration of our work and for the acknowledgement that it adds a new perspective for negative dysphotopsia research.1 The presented in vivo data indeed confirm some of the observations proposed in earlier theoretical ray-tracing analyses on the cause of negative dysphotopsia, such as the smaller pupil size.1–3 For a better understanding of the fundamental cause of negative dysphotopsia, we believe that additional, more patient-specific, analyses are needed because the relevance of these factors for individual patients still has to be determined. These factors include, for instance, the complete IOL design and the retinal shape. Such patient-specific analyses could link the clinical observations, such as visual field eccentricities at which shadowlike effects occur, with the powerful ray-tracing methods proposed in the more theoretical studies.2–4 Personalizing these analyses will, however, require a highly personalized eye model. Such a patient-specific eye model would, for example, include the actual shape and location of the IOL and a personalized retinal shape because they both affect the location at which the shadow is perceived. However, the design of these personalized models requires additional imaging data, such as magnetic resonance imaging, to quantify, for example, the retinal shape.5 The additional benefit of such a personalized model is that it will circumvent the ambiguity in the terminology of the angles between different axes because all elements of the eye will be modeled at their exact position. More importantly, these patient-specific ray-tracing analyses can hopefully confirm the theoretical observed causes of negative dysphotopsia, aiding to design a definite method to prevent or treat this bothersome condition." @default.
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- W3118679080 date "2021-01-01" @default.
- W3118679080 modified "2023-10-14" @default.
- W3118679080 title "Reply to comment on: Distinct differences in anterior chamber configuration and peripheral aberrations in negative dysphotop" @default.
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- W3118679080 doi "https://doi.org/10.1097/j.jcrs.0000000000000431" @default.
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