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- W3118706905 abstract "Illihenin A (1), a novel sesquiterpenoid, was isolated from the roots of Illicium henryi. The structure was determined by spectroscopic analyses, ECD calculation, and single-crystal X-ray diffraction. Compound 1 represents a class of novel 5/7/6 tricyclic sesquiterpenoids featuring a rare cage-like tricyclo[6.2.2.01,5]dodecane core. A plausible biosynthetic pathway of 1 by rearrangement of allo-cedrane is proposed. Additionally, 1 showed potent antiviral activity against coxsackievirus B3 with an IC50 value of 2.87 μM." @default.
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- W3118706905 date "2021-01-05" @default.
- W3118706905 modified "2023-10-13" @default.
- W3118706905 title "Illihenin A: An Antiviral Sesquiterpenoid with a Cage-like Tricyclo[6.2.2.0<sup>1,5</sup>]dodecane Skeleton from <i>Illicium henryi</i>" @default.
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- W3118706905 doi "https://doi.org/10.1021/acs.joc.0c02727" @default.
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