FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3118764624> ?p ?o ?g. }

• W3118764624 abstract "Prednisolone acetate (PNO) and fluorometholone (FRT) are corticosteroids, co-formulated with moxifloxacin HCl (MFX) and cromolyn sodium (CML), respectively. PNO has a negligible quantum yield and its hydrolytic degradation products have enhanced fluorescence, which is 250-fold greater. FRT is a nonfluorescent drug, but its hydrolytic degradation products show reasonable fluorescence; MFX and CML have native fluorescence. Two methods were proposed based on the determination of PNO and FRT via their hydrolytic degradation products in the presence of other degradation products. Method (A) was developed for simultaneous determination of PNO and MFX in the presence of PNO degradation products by measuring peak amplitudes of the first derivative (1D) of its enhanced fluorescence; PNO and MFX were measured at 345 and 473 nm, respectively. Method (B) is a synchronous fluorescence spectroscopic method for simultaneous determination of FRT and its co-formulated drug CML in the presence of its degradation products. Fluorescence intensities were measured at λem 283 and 347 nm for FRT and CML, respectively, using Δλ = 99.20 nm. Validation of the proposed methods was conducted as per International Council for Harmonisation (ICH) guidelines. The proposed methods were successfully applied for the determination of the proposed drugs in bulk powder, ophthalmic solution, and rabbit's aqueous humour." @default.
• W3118764624 created "2021-01-18" @default.
• W3118764624 creator A5007021496 @default.
• W3118764624 creator A5029193461 @default.
• W3118764624 creator A5044089938 @default.
• W3118764624 creator A5060691945 @default.
• W3118764624 creator A5090129814 @default.
• W3118764624 date "2021-04-16" @default.
• W3118764624 modified "2023-09-26" @default.
• W3118764624 title "Selective spectrofluorimetric determination of two corticosteroids along with their co‐formulated drugs and degradation products in ophthalmic solution and aqueous humour" @default.
• W3118764624 cites W1854285661 @default.
• W3118764624 cites W1963592278 @default.
• W3118764624 cites W1964028293 @default.
• W3118764624 cites W1965738489 @default.
• W3118764624 cites W1974192312 @default.
• W3118764624 cites W1985135448 @default.
• W3118764624 cites W1987915008 @default.
• W3118764624 cites W2003535088 @default.
• W3118764624 cites W2005264851 @default.
• W3118764624 cites W2005916027 @default.
• W3118764624 cites W2026014423 @default.
• W3118764624 cites W2032676778 @default.
• W3118764624 cites W2033437714 @default.
• W3118764624 cites W2058483540 @default.
• W3118764624 cites W2059824241 @default.
• W3118764624 cites W2063622054 @default.
• W3118764624 cites W2064188784 @default.
• W3118764624 cites W2078537069 @default.
• W3118764624 cites W2085111811 @default.
• W3118764624 cites W2085436966 @default.
• W3118764624 cites W2088663309 @default.
• W3118764624 cites W2088879760 @default.
• W3118764624 cites W2101622054 @default.
• W3118764624 cites W2102419428 @default.
• W3118764624 cites W2104781051 @default.
• W3118764624 cites W2123900744 @default.
• W3118764624 cites W2143695722 @default.
• W3118764624 cites W2146102588 @default.
• W3118764624 cites W2153632831 @default.
• W3118764624 cites W2161743415 @default.
• W3118764624 cites W2169805041 @default.
• W3118764624 cites W2284296611 @default.
• W3118764624 cites W2326737858 @default.
• W3118764624 cites W2511459978 @default.
• W3118764624 cites W2789410089 @default.
• W3118764624 cites W3000610929 @default.
• W3118764624 doi "https://doi.org/10.1002/bio.4011" @default.
• W3118764624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33428823" @default.
• W3118764624 hasPublicationYear "2021" @default.
• W3118764624 type Work @default.
• W3118764624 sameAs 3118764624 @default.
• W3118764624 citedByCount "4" @default.
• W3118764624 countsByYear W31187646242021 @default.
• W3118764624 countsByYear W31187646242022 @default.
• W3118764624 countsByYear W31187646242023 @default.
• W3118764624 crossrefType "journal-article" @default.
• W3118764624 hasAuthorship W3118764624A5007021496 @default.
• W3118764624 hasAuthorship W3118764624A5029193461 @default.
• W3118764624 hasAuthorship W3118764624A5044089938 @default.
• W3118764624 hasAuthorship W3118764624A5060691945 @default.
• W3118764624 hasAuthorship W3118764624A5090129814 @default.
• W3118764624 hasConcept C106159729 @default.
• W3118764624 hasConcept C111771559 @default.
• W3118764624 hasConcept C119128265 @default.
• W3118764624 hasConcept C121332964 @default.
• W3118764624 hasConcept C13965031 @default.
• W3118764624 hasConcept C162324750 @default.
• W3118764624 hasConcept C178790620 @default.
• W3118764624 hasConcept C184651966 @default.
• W3118764624 hasConcept C185592680 @default.
• W3118764624 hasConcept C2779679103 @default.
• W3118764624 hasConcept C41008148 @default.
• W3118764624 hasConcept C43617362 @default.
• W3118764624 hasConcept C62520636 @default.
• W3118764624 hasConcept C76155785 @default.
• W3118764624 hasConcept C91881484 @default.
• W3118764624 hasConcept C94412978 @default.
• W3118764624 hasConceptScore W3118764624C106159729 @default.
• W3118764624 hasConceptScore W3118764624C111771559 @default.
• W3118764624 hasConceptScore W3118764624C119128265 @default.
• W3118764624 hasConceptScore W3118764624C121332964 @default.
• W3118764624 hasConceptScore W3118764624C13965031 @default.
• W3118764624 hasConceptScore W3118764624C162324750 @default.
• W3118764624 hasConceptScore W3118764624C178790620 @default.
• W3118764624 hasConceptScore W3118764624C184651966 @default.
• W3118764624 hasConceptScore W3118764624C185592680 @default.
• W3118764624 hasConceptScore W3118764624C2779679103 @default.
• W3118764624 hasConceptScore W3118764624C41008148 @default.
• W3118764624 hasConceptScore W3118764624C43617362 @default.
• W3118764624 hasConceptScore W3118764624C62520636 @default.
• W3118764624 hasConceptScore W3118764624C76155785 @default.
• W3118764624 hasConceptScore W3118764624C91881484 @default.
• W3118764624 hasConceptScore W3118764624C94412978 @default.
• W3118764624 hasLocation W31187646241 @default.
• W3118764624 hasOpenAccess W3118764624 @default.
• W3118764624 hasPrimaryLocation W31187646241 @default.
• W3118764624 hasRelatedWork W1770049710 @default.
• W3118764624 hasRelatedWork W1976135213 @default.
• W3118764624 hasRelatedWork W2004832763 @default.
• W3118764624 hasRelatedWork W2018716592 @default.

• next