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- W3118979544 abstract "Covering: up to August 2020The dramatic increase in the identification of dimeric natural products generated by microorganisms and plants has played a significant role in drug discovery. The biosynthetic pathways of these products feature inherent dimerization reactions, which are valuable for biosynthetic applications and chemical transformations. The extraordinary mechanisms of the dimerization of secondary metabolites should advance our understanding of the uncommon chemical rules for natural product biosynthesis, which will, in turn, accelerate the discovery of dimeric reactions and molecules in nature and provide promising strategies for the total synthesis of natural products through dimerization. This review focuses on the enzymes involved in the dimerization in the biosynthetic pathway of microbial natural products, with an emphasis on cytochrome P450s, laccases, and intermolecular [4 + 2] cyclases, along with other atypical enzymes. The identification, characterization, and catalytic landscapes of these enzymes are also introduced." @default.
- W3118979544 created "2021-01-18" @default.
- W3118979544 creator A5027293584 @default.
- W3118979544 creator A5070619167 @default.
- W3118979544 creator A5081485810 @default.
- W3118979544 date "2021-01-01" @default.
- W3118979544 modified "2023-10-12" @default.
- W3118979544 title "Enzymatic dimerization in the biosynthetic pathway of microbial natural products" @default.
- W3118979544 cites W10750722 @default.
- W3118979544 cites W1507436219 @default.
- W3118979544 cites W1698351509 @default.
- W3118979544 cites W1728249019 @default.
- W3118979544 cites W1964638521 @default.
- W3118979544 cites W1964749480 @default.
- W3118979544 cites W1965388752 @default.
- W3118979544 cites W1967517192 @default.
- W3118979544 cites W1968016890 @default.
- W3118979544 cites W1972475948 @default.
- W3118979544 cites W1973464977 @default.
- W3118979544 cites W1973629582 @default.
- W3118979544 cites W1977447433 @default.
- W3118979544 cites W1978364654 @default.
- W3118979544 cites W1981151609 @default.
- W3118979544 cites W1981204101 @default.
- W3118979544 cites W1981407107 @default.
- W3118979544 cites W1981582200 @default.
- W3118979544 cites W1982032801 @default.
- W3118979544 cites W1986890739 @default.
- W3118979544 cites W1989162648 @default.
- W3118979544 cites W1989584562 @default.
- W3118979544 cites W1989686253 @default.
- W3118979544 cites W1990850758 @default.
- W3118979544 cites W1990855267 @default.
- W3118979544 cites W1991442909 @default.
- W3118979544 cites W1991659634 @default.
- W3118979544 cites W1991760918 @default.
- W3118979544 cites W1994109253 @default.
- W3118979544 cites W1996620226 @default.
- W3118979544 cites W2001857913 @default.
- W3118979544 cites W2002004746 @default.
- W3118979544 cites W2008161752 @default.
- W3118979544 cites W2009040171 @default.
- W3118979544 cites W2010496825 @default.
- W3118979544 cites W2010521434 @default.
- W3118979544 cites W2011301706 @default.
- W3118979544 cites W2012598119 @default.
- W3118979544 cites W2012643496 @default.
- W3118979544 cites W2016021105 @default.
- W3118979544 cites W2016030430 @default.
- W3118979544 cites W2017952338 @default.
- W3118979544 cites W2018678702 @default.
- W3118979544 cites W2018843050 @default.
- W3118979544 cites W2019309036 @default.
- W3118979544 cites W2019374522 @default.
- W3118979544 cites W2019910161 @default.
- W3118979544 cites W2022836301 @default.
- W3118979544 cites W2023343774 @default.
- W3118979544 cites W2026280244 @default.
- W3118979544 cites W2026762154 @default.
- W3118979544 cites W2031329527 @default.
- W3118979544 cites W2031560830 @default.
- W3118979544 cites W2032154373 @default.
- W3118979544 cites W2033049942 @default.
- W3118979544 cites W2035227992 @default.
- W3118979544 cites W2038735800 @default.
- W3118979544 cites W2040268985 @default.
- W3118979544 cites W2040684338 @default.
- W3118979544 cites W2041984396 @default.
- W3118979544 cites W2043531549 @default.
- W3118979544 cites W2044273730 @default.
- W3118979544 cites W2050943782 @default.
- W3118979544 cites W2053700413 @default.
- W3118979544 cites W2059134180 @default.
- W3118979544 cites W2060142894 @default.
- W3118979544 cites W2060982173 @default.
- W3118979544 cites W2061123740 @default.
- W3118979544 cites W2062741355 @default.
- W3118979544 cites W2063874456 @default.
- W3118979544 cites W2064175688 @default.
- W3118979544 cites W2065304507 @default.
- W3118979544 cites W2065404591 @default.
- W3118979544 cites W2068085067 @default.
- W3118979544 cites W2071182478 @default.
- W3118979544 cites W2071740437 @default.
- W3118979544 cites W2075846826 @default.
- W3118979544 cites W2076277544 @default.
- W3118979544 cites W2076972711 @default.
- W3118979544 cites W2078395913 @default.
- W3118979544 cites W2079895440 @default.
- W3118979544 cites W2080092289 @default.
- W3118979544 cites W2082632980 @default.
- W3118979544 cites W2082717449 @default.
- W3118979544 cites W2083423866 @default.
- W3118979544 cites W2088455266 @default.
- W3118979544 cites W2088905128 @default.
- W3118979544 cites W2089035676 @default.
- W3118979544 cites W2090285259 @default.
- W3118979544 cites W2092631183 @default.