Matches in SemOpenAlex for { <https://semopenalex.org/work/W3118990529> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W3118990529 abstract "Abstract Background: This study aimed to evaluate the prognostic potential of skeletal muscle mass and muscle quality at the level of the third lumbar vertebra (L3) using computerized tomography (CT) images in patients with stage I–III gastric cancer (GC) who underwent curative gastric resection.Methods: Patients with stage I–III GC who underwent curative gastric resection between October 2006 and June 2014 were enrolled in this study. Demographic and clinical parameters were collected and analyzed. The muscle-related parameters (MRPs), such as the area of total abdominal wall musculature (SMA), area of paraspinal muscle (PMA), mean muscle attenuation (MA) within the total abdominal wall musculature (SMMA), and MA in the paraspinal muscle (PMMA), were measured at the L3 level using CT images. The Kaplan-Meier curve analyses and Cox proportional hazards model were applied to the MRPs, demographic, and clinical parameters to explore the overall survival (OS) and disease-free survival (DFS).Results: Overall, data from 339 patients (233 men and 116 women) were analyzed in this study. In the multivariate Cox model, the elderly (hazard ratio [HR] 2.08, 95% confidence interval [CI] 1.30–3.32, p=0.002), total gastrectomy (HR 2.14, 95% CI 1.32–3.48, p=0.002), stage (HR 3.41, 95% CI 2.10–5.54, p<0.001), perineural invasion (HR 2.01, 95% CI 1.02–3.93, p=0.042), prognostic nutritional index (PNI) (HR 0.91, 95% CI 0.88–0.95, p<0.001), and PMMA (HR 2.36, 95% CI 1.47–3.78), p<0.001) were prognostic factors for OS. Similarly, the elderly (HR 1.68, 95% CI 1.09–2.59, p=0.018), total gastrectomy (HR 2.16, 95% CI 1.37–3.38, p<0.001, stage (HR 4.16, 95% CI 2.64–6.54, p<0.001), PNI (HR 0.91, 95% CI 0.87–0.94, p<0.001), and PMMA (HR 2.22, 95% CI 1.42–3.47, p<0.001) were prognostic factors for DFS.Conclusions: PMMA is suggested as a determinant of OS and DFS in stage I through III GC patients who underwent gastrectomy. Because PMMA is a newly characterized parameter in GC, external validation before clinical applications is a prerequisite." @default.
- W3118990529 created "2021-01-18" @default.
- W3118990529 creator A5017184135 @default.
- W3118990529 creator A5069756184 @default.
- W3118990529 creator A5087914265 @default.
- W3118990529 date "2021-01-13" @default.
- W3118990529 modified "2023-09-27" @default.
- W3118990529 title "Mean Muscle Attenuation within Paraspinal Muscle as a Determinant of Survival in Patients with Gastric Cancer Undergoing Gastrectomy" @default.
- W3118990529 doi "https://doi.org/10.21203/rs.3.rs-138661/v1" @default.
- W3118990529 hasPublicationYear "2021" @default.
- W3118990529 type Work @default.
- W3118990529 sameAs 3118990529 @default.
- W3118990529 citedByCount "0" @default.
- W3118990529 crossrefType "posted-content" @default.
- W3118990529 hasAuthorship W3118990529A5017184135 @default.
- W3118990529 hasAuthorship W3118990529A5069756184 @default.
- W3118990529 hasAuthorship W3118990529A5087914265 @default.
- W3118990529 hasBestOaLocation W31189905291 @default.
- W3118990529 hasConcept C121608353 @default.
- W3118990529 hasConcept C126322002 @default.
- W3118990529 hasConcept C141071460 @default.
- W3118990529 hasConcept C146357865 @default.
- W3118990529 hasConcept C151730666 @default.
- W3118990529 hasConcept C207103383 @default.
- W3118990529 hasConcept C2776214593 @default.
- W3118990529 hasConcept C2779959927 @default.
- W3118990529 hasConcept C2780221984 @default.
- W3118990529 hasConcept C2780470880 @default.
- W3118990529 hasConcept C44249647 @default.
- W3118990529 hasConcept C50382708 @default.
- W3118990529 hasConcept C71924100 @default.
- W3118990529 hasConcept C86803240 @default.
- W3118990529 hasConcept C90924648 @default.
- W3118990529 hasConceptScore W3118990529C121608353 @default.
- W3118990529 hasConceptScore W3118990529C126322002 @default.
- W3118990529 hasConceptScore W3118990529C141071460 @default.
- W3118990529 hasConceptScore W3118990529C146357865 @default.
- W3118990529 hasConceptScore W3118990529C151730666 @default.
- W3118990529 hasConceptScore W3118990529C207103383 @default.
- W3118990529 hasConceptScore W3118990529C2776214593 @default.
- W3118990529 hasConceptScore W3118990529C2779959927 @default.
- W3118990529 hasConceptScore W3118990529C2780221984 @default.
- W3118990529 hasConceptScore W3118990529C2780470880 @default.
- W3118990529 hasConceptScore W3118990529C44249647 @default.
- W3118990529 hasConceptScore W3118990529C50382708 @default.
- W3118990529 hasConceptScore W3118990529C71924100 @default.
- W3118990529 hasConceptScore W3118990529C86803240 @default.
- W3118990529 hasConceptScore W3118990529C90924648 @default.
- W3118990529 hasLocation W31189905291 @default.
- W3118990529 hasOpenAccess W3118990529 @default.
- W3118990529 hasPrimaryLocation W31189905291 @default.
- W3118990529 hasRelatedWork W2019483360 @default.
- W3118990529 hasRelatedWork W2412448412 @default.
- W3118990529 hasRelatedWork W2727470870 @default.
- W3118990529 hasRelatedWork W2784453676 @default.
- W3118990529 hasRelatedWork W2789869937 @default.
- W3118990529 hasRelatedWork W3095608374 @default.
- W3118990529 hasRelatedWork W3118990529 @default.
- W3118990529 hasRelatedWork W4213376506 @default.
- W3118990529 hasRelatedWork W4226111105 @default.
- W3118990529 hasRelatedWork W4285729142 @default.
- W3118990529 isParatext "false" @default.
- W3118990529 isRetracted "false" @default.
- W3118990529 magId "3118990529" @default.
- W3118990529 workType "article" @default.