Matches in SemOpenAlex for { <https://semopenalex.org/work/W3119103886> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3119103886 abstract "Fear- and anxiety-related behaviors significantly contribute to an organism's survival. However, exaggerated defensive responses to perceived threat are characteristic of various anxiety disorders, which are the most prevalent form of mental illness in the United States. Discovering the neurobiological mechanisms responsible for defensive behaviors will aid in the development of novel therapeutic interventions. Pavlovian fear conditioning is a widely used laboratory paradigm to study fear-related learning and memory. A major limitation of traditional Pavlovian fear conditioning paradigms is that freezing is the only defensive behavior monitored. We recently developed a modified Pavlovian fear conditioning paradigm that allows us to study both conditioned freezing and flight (also known as escape) behavior within individual subjects. This model employs higher intensity footshocks and a greater number of pairings between the conditioned stimulus and unconditioned stimulus. Additionally, this conditioned flight paradigm utilizes serial presentation of pure tone and white noise auditory stimuli as the conditioned stimulus. Following conditioning in this paradigm, mice exhibit freezing behavior in response to the tone stimulus, and flight responses during the white noise. This conditioning model can be applied to the study of rapid and flexible transitions between behavioral responses necessary for survival." @default.
- W3119103886 created "2021-01-18" @default.
- W3119103886 creator A5046608944 @default.
- W3119103886 creator A5073759596 @default.
- W3119103886 date "2021-01-05" @default.
- W3119103886 modified "2023-09-25" @default.
- W3119103886 title "A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior" @default.
- W3119103886 doi "https://doi.org/10.3791/61536" @default.
- W3119103886 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8593929" @default.
- W3119103886 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33491674" @default.
- W3119103886 hasPublicationYear "2021" @default.
- W3119103886 type Work @default.
- W3119103886 sameAs 3119103886 @default.
- W3119103886 citedByCount "2" @default.
- W3119103886 countsByYear W31191038862022 @default.
- W3119103886 countsByYear W31191038862023 @default.
- W3119103886 crossrefType "journal-article" @default.
- W3119103886 hasAuthorship W3119103886A5046608944 @default.
- W3119103886 hasAuthorship W3119103886A5073759596 @default.
- W3119103886 hasBestOaLocation W31191038862 @default.
- W3119103886 hasConcept C105021932 @default.
- W3119103886 hasConcept C105795698 @default.
- W3119103886 hasConcept C118552586 @default.
- W3119103886 hasConcept C138496976 @default.
- W3119103886 hasConcept C15744967 @default.
- W3119103886 hasConcept C16837860 @default.
- W3119103886 hasConcept C169760540 @default.
- W3119103886 hasConcept C180747234 @default.
- W3119103886 hasConcept C26760741 @default.
- W3119103886 hasConcept C2779144063 @default.
- W3119103886 hasConcept C2779918689 @default.
- W3119103886 hasConcept C2781069985 @default.
- W3119103886 hasConcept C2988483714 @default.
- W3119103886 hasConcept C3020794659 @default.
- W3119103886 hasConcept C33923547 @default.
- W3119103886 hasConcept C39617858 @default.
- W3119103886 hasConcept C43838033 @default.
- W3119103886 hasConcept C45262634 @default.
- W3119103886 hasConcept C558461103 @default.
- W3119103886 hasConceptScore W3119103886C105021932 @default.
- W3119103886 hasConceptScore W3119103886C105795698 @default.
- W3119103886 hasConceptScore W3119103886C118552586 @default.
- W3119103886 hasConceptScore W3119103886C138496976 @default.
- W3119103886 hasConceptScore W3119103886C15744967 @default.
- W3119103886 hasConceptScore W3119103886C16837860 @default.
- W3119103886 hasConceptScore W3119103886C169760540 @default.
- W3119103886 hasConceptScore W3119103886C180747234 @default.
- W3119103886 hasConceptScore W3119103886C26760741 @default.
- W3119103886 hasConceptScore W3119103886C2779144063 @default.
- W3119103886 hasConceptScore W3119103886C2779918689 @default.
- W3119103886 hasConceptScore W3119103886C2781069985 @default.
- W3119103886 hasConceptScore W3119103886C2988483714 @default.
- W3119103886 hasConceptScore W3119103886C3020794659 @default.
- W3119103886 hasConceptScore W3119103886C33923547 @default.
- W3119103886 hasConceptScore W3119103886C39617858 @default.
- W3119103886 hasConceptScore W3119103886C43838033 @default.
- W3119103886 hasConceptScore W3119103886C45262634 @default.
- W3119103886 hasConceptScore W3119103886C558461103 @default.
- W3119103886 hasIssue "167" @default.
- W3119103886 hasLocation W31191038861 @default.
- W3119103886 hasLocation W31191038862 @default.
- W3119103886 hasLocation W31191038863 @default.
- W3119103886 hasOpenAccess W3119103886 @default.
- W3119103886 hasPrimaryLocation W31191038861 @default.
- W3119103886 hasRelatedWork W1971013024 @default.
- W3119103886 hasRelatedWork W1994915764 @default.
- W3119103886 hasRelatedWork W1997024147 @default.
- W3119103886 hasRelatedWork W2008866602 @default.
- W3119103886 hasRelatedWork W2067357718 @default.
- W3119103886 hasRelatedWork W2096673396 @default.
- W3119103886 hasRelatedWork W3119103886 @default.
- W3119103886 hasRelatedWork W4236944604 @default.
- W3119103886 hasRelatedWork W4246303119 @default.
- W3119103886 hasRelatedWork W4251292323 @default.
- W3119103886 isParatext "false" @default.
- W3119103886 isRetracted "false" @default.
- W3119103886 magId "3119103886" @default.
- W3119103886 workType "article" @default.