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- W3119303949 abstract "Objective To provide a concise review of the literature on desmopressin use for antiplatelet reversal in patients with intracranial hemorrhage. Data Sources Source data were obtained from a PubMed literature review. Study Selection: Studies addressing desmopressin for antiplatelet reversal. Data Extraction: Relevant studies were reviewed and included through consensus of the authors. The following aspects of each study were identified, abstracted, and analyzed: study population, study design, methods, results, and relevant implications for practice. Data Synthesis A growing body of evidence continues to provide mixed results for the use of desmopressin in patients presenting with antiplatelet-associated intracranial hemorrhage. The potential benefit outweighs the possible risks associated with a one-time dose. In addition to desmopressin, platelets should only be considered in patients undergoing a neurosurgical procedure until further and superior evidence is available. Guidelines recommend a weight-based approach for desmopressin dosing at 0.4 mcg/kg over 30 min. Conclusions The available evidence supports desmopressin as potentially beneficial with minimal risk for use in patients with antiplatelet-associated intracranial hemorrhage." @default.
- W3119303949 created "2021-01-18" @default.
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- W3119303949 date "2021-01-01" @default.
- W3119303949 modified "2023-09-26" @default.
- W3119303949 title "Desmopressin for Antiplatelet-Associated Intracranial Hemorrhage: A Concise Review" @default.
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- W3119303949 doi "https://doi.org/10.1097/jtn.0000000000000558" @default.
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