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- W3119346475 endingPage "109" @default.
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- W3119346475 abstract "Articular cartilage regeneration is one of the challenges faced by orthopedic surgeons. Microcarrier applications have made great advances in cartilage tissue engineering in recent years and enable cost-effective cell expansion, thus providing permissive microenvironments for cells. In addition, microcarriers can be loaded with proteins, factors, and drugs for cartilage regeneration. Some microcarriers also have the advantages of injectability and targeted delivery. The application of microcarriers with these characteristics can overcome the limitations of traditional methods and provide additional advantages. In terms of the transformation potential, microcarriers have not only many advantages, such as providing sufficient and beneficial cells, factors, drugs, and microenvironments for cartilage regeneration, but also many application characteristics; for example, they can be injected to reduce invasiveness, transplanted after microtissue formation to increase efficiency, or combined with other stents to improve mechanical properties. Therefore, this technology has enormous potential for clinical transformation. In this review, we focus on recent advances in microcarriers for cartilage regeneration. We compare the characteristics of microcarriers with other methods for repairing cartilage defects, provide an overview of the advantages of microcarriers, discuss the potential of microcarrier systems, and present an outlook for future development.We reviewed the advantages and recent advances of microcarriers for cartilage regeneration. This review could give many scholars a better understanding of microcarriers, which can provide doctors with potential methods for treating patients with cartilage injure." @default.
- W3119346475 created "2021-01-18" @default.
- W3119346475 creator A5000501514 @default.
- W3119346475 creator A5022387079 @default.
- W3119346475 creator A5040162149 @default.
- W3119346475 creator A5043895978 @default.
- W3119346475 creator A5044565573 @default.
- W3119346475 creator A5046606410 @default.
- W3119346475 creator A5046756339 @default.
- W3119346475 creator A5060817955 @default.
- W3119346475 creator A5083599448 @default.
- W3119346475 date "2021-03-01" @default.
- W3119346475 modified "2023-10-14" @default.
- W3119346475 title "Potential and recent advances of microcarriers in repairing cartilage defects" @default.
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