Matches in SemOpenAlex for { <https://semopenalex.org/work/W3119496780> ?p ?o ?g. }
- W3119496780 abstract "Abstract In the midst of a pandemic, serologic studies are a valuable tool to understand the course of the outbreak and guide public health and general pandemic management. However, given significant safety constraints including social distancing and stay-at-home orders, sample collection becomes more difficult given traditional phlebotomy protocols. For such studies, a representative sample of the underlying population is paramount to elicit meaningful insights that capture the spread of the infection, particularly when different sub-populations face varying disease burden. We aimed to address these challenges by conducting a fully remote study to investigate the seroprevalence of SARS-CoV-2 in the state of Massachusetts. Leveraging electronic study engagement and at-home self-collection of finger-prick samples, we enrolled 2,066 participants representative of the ethnic and racial composition of Massachusetts. SARS-CoV-2 total IgG seropositivity was 3.15%, and follow-up measurements at days 7, 15, 45, and 90 indicate a generally durable antibody response. A higher risk of infection was observed for healthcare workers and their cohabitants and those with comorbidities, as well as lower-income, less educated, Hispanic, and those in the age groups of 18-29 and 50-59-years-old. High engagement and positive feedback from the participants and quality of self-collected specimens point to the usefulness of this design for future population-level serological studies that more effectively and safely reach a broad representative cohort, thus yielding more comprehensive insights into the burden of infection and disease in populations. Key points Question We aimed to implement a fully remote seroprevalence study for SARS-CoV-2, leveraging electronic methods and at-home self-collection of specimens to engage a representative study population. Findings The population enrolled reflected the ethnic and racial composition of Massachusetts, revealing a SARS-CoV-2 seroprevalence of 3.15% and higher risk of previous infection associated with healthcare workers/their cohabitants, those with comorbidities, lower-income, less educated, Hispanic, and those in age groups 18-29 and 50-59 years old. Meaning High engagement and positive feedback from participants as well as quality of self-collected specimens point to the usefulness of this design for future population-level serological studies." @default.
- W3119496780 created "2021-01-18" @default.
- W3119496780 creator A5003283905 @default.
- W3119496780 creator A5013936854 @default.
- W3119496780 creator A5039064560 @default.
- W3119496780 creator A5048193436 @default.
- W3119496780 creator A5048392297 @default.
- W3119496780 creator A5053336292 @default.
- W3119496780 creator A5054269063 @default.
- W3119496780 creator A5055894900 @default.
- W3119496780 creator A5062631758 @default.
- W3119496780 creator A5082922219 @default.
- W3119496780 date "2021-01-15" @default.
- W3119496780 modified "2023-09-27" @default.
- W3119496780 title "Development of at-home sample collection logistics for large scale SARS-CoV-2 seroprevalence studies" @default.
- W3119496780 cites W3001456238 @default.
- W3119496780 cites W3007298159 @default.
- W3119496780 cites W3007497549 @default.
- W3119496780 cites W3009906937 @default.
- W3119496780 cites W3012804303 @default.
- W3119496780 cites W3012846954 @default.
- W3119496780 cites W3013800395 @default.
- W3119496780 cites W3017101752 @default.
- W3119496780 cites W3017185871 @default.
- W3119496780 cites W3023031160 @default.
- W3119496780 cites W3023118558 @default.
- W3119496780 cites W3024982296 @default.
- W3119496780 cites W3027576812 @default.
- W3119496780 cites W3035189381 @default.
- W3119496780 cites W3036402194 @default.
- W3119496780 cites W3036931136 @default.
- W3119496780 cites W3042443640 @default.
- W3119496780 cites W3083820245 @default.
- W3119496780 cites W3087128437 @default.
- W3119496780 cites W3088647268 @default.
- W3119496780 cites W3092050672 @default.
- W3119496780 cites W3094968263 @default.
- W3119496780 cites W3096816634 @default.
- W3119496780 doi "https://doi.org/10.1101/2021.01.14.21249824" @default.
- W3119496780 hasPublicationYear "2021" @default.
- W3119496780 type Work @default.
- W3119496780 sameAs 3119496780 @default.
- W3119496780 citedByCount "0" @default.
- W3119496780 crossrefType "posted-content" @default.
- W3119496780 hasAuthorship W3119496780A5003283905 @default.
- W3119496780 hasAuthorship W3119496780A5013936854 @default.
- W3119496780 hasAuthorship W3119496780A5039064560 @default.
- W3119496780 hasAuthorship W3119496780A5048193436 @default.
- W3119496780 hasAuthorship W3119496780A5048392297 @default.
- W3119496780 hasAuthorship W3119496780A5053336292 @default.
- W3119496780 hasAuthorship W3119496780A5054269063 @default.
- W3119496780 hasAuthorship W3119496780A5055894900 @default.
- W3119496780 hasAuthorship W3119496780A5062631758 @default.
- W3119496780 hasAuthorship W3119496780A5082922219 @default.
- W3119496780 hasBestOaLocation W31194967801 @default.
- W3119496780 hasConcept C116675565 @default.
- W3119496780 hasConcept C137403100 @default.
- W3119496780 hasConcept C138816342 @default.
- W3119496780 hasConcept C142724271 @default.
- W3119496780 hasConcept C144024400 @default.
- W3119496780 hasConcept C149923435 @default.
- W3119496780 hasConcept C159047783 @default.
- W3119496780 hasConcept C159110408 @default.
- W3119496780 hasConcept C159654299 @default.
- W3119496780 hasConcept C172656115 @default.
- W3119496780 hasConcept C185592680 @default.
- W3119496780 hasConcept C19165224 @default.
- W3119496780 hasConcept C198531522 @default.
- W3119496780 hasConcept C203014093 @default.
- W3119496780 hasConcept C205649164 @default.
- W3119496780 hasConcept C2778494684 @default.
- W3119496780 hasConcept C2778755073 @default.
- W3119496780 hasConcept C2779134260 @default.
- W3119496780 hasConcept C2908647359 @default.
- W3119496780 hasConcept C3008058167 @default.
- W3119496780 hasConcept C43617362 @default.
- W3119496780 hasConcept C45189115 @default.
- W3119496780 hasConcept C512399662 @default.
- W3119496780 hasConcept C524204448 @default.
- W3119496780 hasConcept C58640448 @default.
- W3119496780 hasConcept C71924100 @default.
- W3119496780 hasConcept C74909509 @default.
- W3119496780 hasConcept C89623803 @default.
- W3119496780 hasConcept C99454951 @default.
- W3119496780 hasConceptScore W3119496780C116675565 @default.
- W3119496780 hasConceptScore W3119496780C137403100 @default.
- W3119496780 hasConceptScore W3119496780C138816342 @default.
- W3119496780 hasConceptScore W3119496780C142724271 @default.
- W3119496780 hasConceptScore W3119496780C144024400 @default.
- W3119496780 hasConceptScore W3119496780C149923435 @default.
- W3119496780 hasConceptScore W3119496780C159047783 @default.
- W3119496780 hasConceptScore W3119496780C159110408 @default.
- W3119496780 hasConceptScore W3119496780C159654299 @default.
- W3119496780 hasConceptScore W3119496780C172656115 @default.
- W3119496780 hasConceptScore W3119496780C185592680 @default.
- W3119496780 hasConceptScore W3119496780C19165224 @default.
- W3119496780 hasConceptScore W3119496780C198531522 @default.
- W3119496780 hasConceptScore W3119496780C203014093 @default.
- W3119496780 hasConceptScore W3119496780C205649164 @default.
- W3119496780 hasConceptScore W3119496780C2778494684 @default.