Matches in SemOpenAlex for { <https://semopenalex.org/work/W3119519284> ?p ?o ?g. }
- W3119519284 endingPage "109524" @default.
- W3119519284 startingPage "109524" @default.
- W3119519284 abstract "Purpose To investigate the impact of positron emission tomography/computed tomography (PET/CT) on clinical management in patients with esophageal cancer and its link to overall survival (OS) in a real-world setting. Methods A patient cohort with advanced esophageal cancer undergoing PET/CT was prospectively enrolled in a registry study between 04/2013 and 06/2019. Intended patient management prior and after PET/CT was documented based on standardized questionnaire data. Management changes after PET/CT were recorded including major changes concerning the treatment goal (curative vs. palliative) and minor changes (therapy adjustments). OS was analyzed for subgroups with squamous cell carcinomas (SCC) or adenocarcinomas (AC) and stratified for extent of metastatic disease and treatment goals. Results 257 patients (53 female;65.5 ± 10.0 yr.) were included. After PET/CT, major changes of intended therapy were observed in 34/257 patients (13.2%), from curative to palliative (8.2%), palliative to curative (1.9%) and from “not finally determined” to a curative (1.9%) or palliative (1.2%) concept. Minor changes were found in 62/257 patients (24.1%). Invasive procedures and additional imaging were intended in 70/257 (27.2%) and 94/257 (36.6%) patients before PET/CT and 20/257 (7.8%) and 8/257 (3.1%) patients after PET/CT. Curative therapy concepts based on PET/CT were associated with a longer OS (3.5 yr.[95%CI 3.1–3.8 yr.]) as compared to palliative concepts (0.9 yr.[95%CI 0.6–1.2 yr.];p < 0.0001). Patients with SCC had a worse prognosis (2.4 yr.[95%CI 2.0–2.9 yr.]) as compared to patients with AC (3.2 yr.[95%CI 2.7–3.7 yr.];p = 0.01). Conclusions In patients with advanced esophageal cancer, PET/CT has a significant impact on clinical management by improving the selection of individualized treatment strategies and avoiding additional diagnostic procedures." @default.
- W3119519284 created "2021-01-18" @default.
- W3119519284 creator A5014041342 @default.
- W3119519284 creator A5025657000 @default.
- W3119519284 creator A5035295206 @default.
- W3119519284 creator A5040615086 @default.
- W3119519284 creator A5080097591 @default.
- W3119519284 creator A5082886545 @default.
- W3119519284 creator A5089705974 @default.
- W3119519284 date "2021-03-01" @default.
- W3119519284 modified "2023-10-06" @default.
- W3119519284 title "Impact of PET/CT on management of patients with esophageal cancer – results from a PET/CT registry study" @default.
- W3119519284 cites W1894295571 @default.
- W3119519284 cites W1965267867 @default.
- W3119519284 cites W1976830577 @default.
- W3119519284 cites W1981596218 @default.
- W3119519284 cites W1986119528 @default.
- W3119519284 cites W2003550855 @default.
- W3119519284 cites W2009626729 @default.
- W3119519284 cites W2035829727 @default.
- W3119519284 cites W2037329074 @default.
- W3119519284 cites W2040729567 @default.
- W3119519284 cites W2074624172 @default.
- W3119519284 cites W2078678980 @default.
- W3119519284 cites W2081400771 @default.
- W3119519284 cites W2087826080 @default.
- W3119519284 cites W2094440911 @default.
- W3119519284 cites W2099918668 @default.
- W3119519284 cites W2110368430 @default.
- W3119519284 cites W2116076046 @default.
- W3119519284 cites W2122054855 @default.
- W3119519284 cites W2129779870 @default.
- W3119519284 cites W2130497983 @default.
- W3119519284 cites W2131010317 @default.
- W3119519284 cites W2135725800 @default.
- W3119519284 cites W2155689719 @default.
- W3119519284 cites W2892861663 @default.
- W3119519284 cites W2897601187 @default.
- W3119519284 cites W2921110418 @default.
- W3119519284 cites W3093471252 @default.
- W3119519284 cites W4211048478 @default.
- W3119519284 cites W4249441028 @default.
- W3119519284 cites W4252560545 @default.
- W3119519284 doi "https://doi.org/10.1016/j.ejrad.2021.109524" @default.
- W3119519284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33434862" @default.
- W3119519284 hasPublicationYear "2021" @default.
- W3119519284 type Work @default.
- W3119519284 sameAs 3119519284 @default.
- W3119519284 citedByCount "3" @default.
- W3119519284 countsByYear W31195192842022 @default.
- W3119519284 countsByYear W31195192842023 @default.
- W3119519284 crossrefType "journal-article" @default.
- W3119519284 hasAuthorship W3119519284A5014041342 @default.
- W3119519284 hasAuthorship W3119519284A5025657000 @default.
- W3119519284 hasAuthorship W3119519284A5035295206 @default.
- W3119519284 hasAuthorship W3119519284A5040615086 @default.
- W3119519284 hasAuthorship W3119519284A5080097591 @default.
- W3119519284 hasAuthorship W3119519284A5082886545 @default.
- W3119519284 hasAuthorship W3119519284A5089705974 @default.
- W3119519284 hasConcept C121608353 @default.
- W3119519284 hasConcept C126322002 @default.
- W3119519284 hasConcept C126838900 @default.
- W3119519284 hasConcept C127077266 @default.
- W3119519284 hasConcept C159110408 @default.
- W3119519284 hasConcept C2775842073 @default.
- W3119519284 hasConcept C2779742542 @default.
- W3119519284 hasConcept C2989005 @default.
- W3119519284 hasConcept C2994186709 @default.
- W3119519284 hasConcept C71924100 @default.
- W3119519284 hasConceptScore W3119519284C121608353 @default.
- W3119519284 hasConceptScore W3119519284C126322002 @default.
- W3119519284 hasConceptScore W3119519284C126838900 @default.
- W3119519284 hasConceptScore W3119519284C127077266 @default.
- W3119519284 hasConceptScore W3119519284C159110408 @default.
- W3119519284 hasConceptScore W3119519284C2775842073 @default.
- W3119519284 hasConceptScore W3119519284C2779742542 @default.
- W3119519284 hasConceptScore W3119519284C2989005 @default.
- W3119519284 hasConceptScore W3119519284C2994186709 @default.
- W3119519284 hasConceptScore W3119519284C71924100 @default.
- W3119519284 hasFunder F4320320879 @default.
- W3119519284 hasFunder F4320335385 @default.
- W3119519284 hasLocation W31195192841 @default.
- W3119519284 hasOpenAccess W3119519284 @default.
- W3119519284 hasPrimaryLocation W31195192841 @default.
- W3119519284 hasRelatedWork W2021729604 @default.
- W3119519284 hasRelatedWork W2037617828 @default.
- W3119519284 hasRelatedWork W2070705913 @default.
- W3119519284 hasRelatedWork W2080502759 @default.
- W3119519284 hasRelatedWork W2107701361 @default.
- W3119519284 hasRelatedWork W2281964991 @default.
- W3119519284 hasRelatedWork W2340181983 @default.
- W3119519284 hasRelatedWork W2731120814 @default.
- W3119519284 hasRelatedWork W2909852936 @default.
- W3119519284 hasRelatedWork W2951337402 @default.
- W3119519284 hasVolume "136" @default.
- W3119519284 isParatext "false" @default.
- W3119519284 isRetracted "false" @default.
- W3119519284 magId "3119519284" @default.