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• W3119592357 abstract "The subcutaneous implantable cardioverter defibrillator (S-ICD) has been considered as a comparable alternative to transvenous ICD in a wide array of patients (pts) without pacing indication. Recent data have reported high rates of inappropriate (inap) therapies with S-ICD, mostly due to T wave or noise oversensing. Our aim was to assess the predictive factors of inap therapies over a mid-term follow-up (FU) period after SICD implantation. All pts implanted with an S-ICD and a FU above 6 months were included in a cross-sectional monocentric study. Data from preoperative screening with a thorough ECG study (amplitude of QRS complex, T wave and QRS:T ratio in leads I, II and III) has been collected. Pts were followed by remote monitoring. One hundred and twenty-four pts (50 ± 14 years old, male 84%) were included. Indications were: primary 73% and secondary prevention 27% (ischemic cardiopathy 39%; hypertrophic 8%; dilated 36%; channelopathy 2%). During a mean FU of 25 ± 16 months, 29 pts (23%) experienced at least one therapy: 15 pts with appropriate (12%) and 15 pts with inap shocks (12%). A total of 22 inap shocks have been observed after a mean FU period of 15 ± 18 months (1.5 ± 1 inap shock per pt, several shocks for 4 pts). Causes were: supraventricular arrhythmias (33%), T wave (20%) and noise (53%) oversensing. The number of eligible vectors during preoperative screening was correlated with the occurrence of inap shocks (−0.23; P < 0.05). ECG criteria measured in lead I were significantly correlated with inap therapies: QRS and T wave amplitude, respectively −0.23 and 0.3 (P < 0.01), and the QRS:T ratio in lead I (−0.34; P < 0.01). Of note, the untreated events related to T wave or noise oversensing during the FU were correlated with inap shocks (0.32; P < 0.01) (Fig. 1). Inap therapies remain frequent with S-ICD. Preoperative screening (number of eligible vectors) and ECG data may be taken into consideration to identify patients at high risk for inap shocks." @default.
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• W3119592357 date "2021-01-01" @default.
• W3119592357 modified "2023-10-16" @default.
• W3119592357 title "Predictive factors of inappropriate therapies in subcutaneous implantable cardioverter defibrillators" @default.
• W3119592357 doi "https://doi.org/10.1016/j.acvdsp.2020.10.211" @default.
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