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• W3119638322 abstract "Abstract Background To assess the clinical and survival features of nasopharyngeal carcinoma (NPC) with consistently negative Epstein–Barr virus (EBV) DNA level. Methods Propensity score matching (PSM) method was used to create well‐balanced cohorts. Kaplan–Meier method and Cox proportional hazards models were performed to conduct survival analysis. Results Four hundred and eighty patients were enrolled. Patients with consistently negative plasma EBV DNA level had a greater chance to present a relatively earlier T and N classification compared with those with positive EBV DNA level ( p < .001; p = .015). And patients with consistently negative EBV level were significantly associated with preferable 3‐year DFS (95.0% vs. 84.4%, p = .004), DMFS (98.3% vs. 89.4%, p = .009), and OS (100% vs. 97.6%, p = .004). Conclusions NPC patients with consistently negative EBV DNA level performed an earlier clinical stage and negative EBV DNA level was related to preferable survival outcomes." @default.
• W3119638322 created "2021-01-18" @default.
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• W3119638322 date "2021-01-09" @default.
• W3119638322 modified "2023-09-23" @default.
• W3119638322 title "Clinical and survival analysis of nasopharyngeal carcinoma with consistently negative <scp>Epstein–Barr</scp> virus <scp>DNA</scp>" @default.
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• W3119638322 doi "https://doi.org/10.1002/hed.26608" @default.
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