FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3119690284> ?p ?o ?g. }

• W3119690284 endingPage "S121" @default.
• W3119690284 startingPage "S113" @default.
• W3119690284 abstract "We aimed to carry out proteomic assessment of long-term effects of hepatitis C on liver.Cirrhosis is a condition where liver is damaged and loses its efficiency, and has the high rate of mortality in the world. Proteome profiling may help to identify important proteins and find the pathogenesis Cirrhosis is a condition where liver is damaged and loses its efficiency, and has the high rate of mortality in the world. Proteome profiling may help to identify important proteins and find the pathogenesis.Here, by the application of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE), combined with (MALDI-TOF-TOF MS), proteome profile of decompensated HCV cirrhosis is determined compared to healthy matched controls. Furthermore, Cytoscape has used network analysis. The proteome comparison between two groups identified proteins with significant expression changes (p<0.05 and fold change ≥ 1.5).We found upregulation of IGHA1, C3, A1BG, IGKC and one isoform of HP. Also, lower expression of APOA4 and the other spot of HP in advanced cirrhosis patients were revealed based on HCV compared to matched controls. According to network analysis, ALB has been introduced as a key protein, which may play an important role in pathogenesis.Integration of the proteomics with protein interaction data led to the identification of several novel key proteins related to the immune system that may reflect the long-term effects of hepatitis C virus on the liver, and can introduce as therapeutic targets for advanced HCV- cirrhosis." @default.
• W3119690284 created "2021-01-18" @default.
• W3119690284 creator A5005182739 @default.
• W3119690284 creator A5018739716 @default.
• W3119690284 creator A5037003858 @default.
• W3119690284 creator A5069425430 @default.
• W3119690284 creator A5090852115 @default.
• W3119690284 date "2020-01-01" @default.
• W3119690284 modified "2023-09-23" @default.
• W3119690284 title "Proteomic study of advanced cirrhosis based on HCV to reveal potential biomarkers." @default.
• W3119690284 cites W1521038038 @default.
• W3119690284 cites W1664037137 @default.
• W3119690284 cites W166911324 @default.
• W3119690284 cites W1712474551 @default.
• W3119690284 cites W1880992190 @default.
• W3119690284 cites W1977914294 @default.
• W3119690284 cites W1985837317 @default.
• W3119690284 cites W1987615431 @default.
• W3119690284 cites W1994597779 @default.
• W3119690284 cites W1994848817 @default.
• W3119690284 cites W2004352660 @default.
• W3119690284 cites W2022305296 @default.
• W3119690284 cites W2026682777 @default.
• W3119690284 cites W2043076359 @default.
• W3119690284 cites W2046190943 @default.
• W3119690284 cites W2050594060 @default.
• W3119690284 cites W2053433997 @default.
• W3119690284 cites W207675605 @default.
• W3119690284 cites W2080124998 @default.
• W3119690284 cites W2096394150 @default.
• W3119690284 cites W2102040488 @default.
• W3119690284 cites W2111288662 @default.
• W3119690284 cites W2112187659 @default.
• W3119690284 cites W2116345835 @default.
• W3119690284 cites W2121493480 @default.
• W3119690284 cites W2121913440 @default.
• W3119690284 cites W2136563184 @default.
• W3119690284 cites W2138392157 @default.
• W3119690284 cites W2138482047 @default.
• W3119690284 cites W2141975506 @default.
• W3119690284 cites W2144815078 @default.
• W3119690284 cites W2150318080 @default.
• W3119690284 cites W2152319801 @default.
• W3119690284 cites W2159675211 @default.
• W3119690284 cites W2168292193 @default.
• W3119690284 cites W2169589032 @default.
• W3119690284 cites W2206147190 @default.
• W3119690284 cites W2294217228 @default.
• W3119690284 cites W2300185447 @default.
• W3119690284 cites W2311381518 @default.
• W3119690284 cites W2330563949 @default.
• W3119690284 cites W293145219 @default.
• W3119690284 cites W4211260107 @default.
• W3119690284 cites W58991726 @default.
• W3119690284 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7881408" @default.
• W3119690284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33585012" @default.
• W3119690284 hasPublicationYear "2020" @default.
• W3119690284 type Work @default.
• W3119690284 sameAs 3119690284 @default.
• W3119690284 citedByCount "0" @default.
• W3119690284 crossrefType "journal-article" @default.
• W3119690284 hasAuthorship W3119690284A5005182739 @default.
• W3119690284 hasAuthorship W3119690284A5018739716 @default.
• W3119690284 hasAuthorship W3119690284A5037003858 @default.
• W3119690284 hasAuthorship W3119690284A5069425430 @default.
• W3119690284 hasAuthorship W3119690284A5090852115 @default.
• W3119690284 hasConcept C104317684 @default.
• W3119690284 hasConcept C104397665 @default.
• W3119690284 hasConcept C126322002 @default.
• W3119690284 hasConcept C127561419 @default.
• W3119690284 hasConcept C203014093 @default.
• W3119690284 hasConcept C2522874641 @default.
• W3119690284 hasConcept C2776408679 @default.
• W3119690284 hasConcept C2776455275 @default.
• W3119690284 hasConcept C2777214474 @default.
• W3119690284 hasConcept C2779018089 @default.
• W3119690284 hasConcept C2780942790 @default.
• W3119690284 hasConcept C46111723 @default.
• W3119690284 hasConcept C54355233 @default.
• W3119690284 hasConcept C60644358 @default.
• W3119690284 hasConcept C70721500 @default.
• W3119690284 hasConcept C71924100 @default.
• W3119690284 hasConcept C86803240 @default.
• W3119690284 hasConceptScore W3119690284C104317684 @default.
• W3119690284 hasConceptScore W3119690284C104397665 @default.
• W3119690284 hasConceptScore W3119690284C126322002 @default.
• W3119690284 hasConceptScore W3119690284C127561419 @default.
• W3119690284 hasConceptScore W3119690284C203014093 @default.
• W3119690284 hasConceptScore W3119690284C2522874641 @default.
• W3119690284 hasConceptScore W3119690284C2776408679 @default.
• W3119690284 hasConceptScore W3119690284C2776455275 @default.
• W3119690284 hasConceptScore W3119690284C2777214474 @default.
• W3119690284 hasConceptScore W3119690284C2779018089 @default.
• W3119690284 hasConceptScore W3119690284C2780942790 @default.
• W3119690284 hasConceptScore W3119690284C46111723 @default.
• W3119690284 hasConceptScore W3119690284C54355233 @default.
• W3119690284 hasConceptScore W3119690284C60644358 @default.
• W3119690284 hasConceptScore W3119690284C70721500 @default.

• next