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• W3119781569 abstract "The human adult liver has a multi-cellular structure consisting of large lobes subdivided into lobules containing portal triads and hepatic cords lined by specialized blood vessels. Vital hepatic functions include filtering blood, metabolizing drugs, and production of bile and blood plasma proteins like albumin, among many other functions, which are generally dependent on the location or zone in which the hepatocyte resides in the liver. Due to the liver's intricate structure, there are many challenges to design differentiation protocols to generate more mature functional hepatocytes from human stem cells and maintain the long-term viability and functionality of primary hepatocytes. To this end, recent advancements in three-dimensional (3D) stem cell culture have accelerated the generation of a human miniature liver system, also known as liver organoids, with polarized epithelial cells, supportive cell types and extra-cellular matrix deposition by translating knowledge gained in studies of animal organogenesis and regeneration. To facilitate the efforts to study human development and disease using in vitro hepatic models, a thorough understanding of state-of-art protocols and underlying rationales is essential. Here, we review rapidly evolving 3D liver models, mainly focusing on organoid models differentiated from human cells." @default.
• W3119781569 created "2021-01-18" @default.
• W3119781569 creator A5034580309 @default.
• W3119781569 creator A5085290996 @default.
• W3119781569 date "2021-01-01" @default.
• W3119781569 modified "2023-10-10" @default.
• W3119781569 title "Human liver model systems in a dish" @default.
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• W3119781569 cites W1968832732 @default.
• W3119781569 cites W1986947784 @default.
• W3119781569 cites W1990570289 @default.
• W3119781569 cites W1999914688 @default.
• W3119781569 cites W2000151960 @default.
• W3119781569 cites W2007260996 @default.
• W3119781569 cites W2008365696 @default.
• W3119781569 cites W2020755558 @default.
• W3119781569 cites W2030338281 @default.
• W3119781569 cites W2038404321 @default.
• W3119781569 cites W2043915076 @default.
• W3119781569 cites W2054361177 @default.
• W3119781569 cites W2061101624 @default.
• W3119781569 cites W2077748688 @default.
• W3119781569 cites W2079277029 @default.
• W3119781569 cites W2084090163 @default.
• W3119781569 cites W2084398087 @default.
• W3119781569 cites W2085652695 @default.
• W3119781569 cites W2087315598 @default.
• W3119781569 cites W2093764045 @default.
• W3119781569 cites W2105329616 @default.
• W3119781569 cites W2119907914 @default.
• W3119781569 cites W2123743609 @default.
• W3119781569 cites W2134520937 @default.
• W3119781569 cites W2201162837 @default.
• W3119781569 cites W2264718512 @default.
• W3119781569 cites W2331628193 @default.
• W3119781569 cites W2345415005 @default.
• W3119781569 cites W2370483985 @default.
• W3119781569 cites W2463366105 @default.
• W3119781569 cites W2470369424 @default.
• W3119781569 cites W2520824012 @default.
• W3119781569 cites W2552754421 @default.
• W3119781569 cites W2582439362 @default.
• W3119781569 cites W2592130743 @default.
• W3119781569 cites W2613180696 @default.
• W3119781569 cites W2625311319 @default.
• W3119781569 cites W2626990934 @default.
• W3119781569 cites W2735484642 @default.
• W3119781569 cites W2741286864 @default.
• W3119781569 cites W2750265290 @default.
• W3119781569 cites W2752005606 @default.
• W3119781569 cites W2757407722 @default.
• W3119781569 cites W2771057425 @default.
• W3119781569 cites W2772609750 @default.
• W3119781569 cites W2784187065 @default.
• W3119781569 cites W2785809303 @default.
• W3119781569 cites W2807476445 @default.
• W3119781569 cites W2883298821 @default.
• W3119781569 cites W2883652711 @default.
• W3119781569 cites W2896011625 @default.
• W3119781569 cites W2900240008 @default.
• W3119781569 cites W2903148550 @default.
• W3119781569 cites W2905989315 @default.
• W3119781569 cites W2907789384 @default.
• W3119781569 cites W2917788812 @default.
• W3119781569 cites W2939812575 @default.
• W3119781569 cites W2945483640 @default.
• W3119781569 cites W2946842680 @default.
• W3119781569 cites W2949380546 @default.
• W3119781569 cites W2956005250 @default.
• W3119781569 cites W2958817003 @default.
• W3119781569 cites W2959932413 @default.
• W3119781569 cites W2964772567 @default.
• W3119781569 cites W2965452585 @default.
• W3119781569 cites W2965996124 @default.
• W3119781569 cites W2972883372 @default.
• W3119781569 cites W2976165305 @default.
• W3119781569 cites W2976500971 @default.
• W3119781569 cites W2976549303 @default.
• W3119781569 cites W2977786572 @default.
• W3119781569 cites W2980585186 @default.
• W3119781569 cites W2996616519 @default.
• W3119781569 cites W3007661294 @default.
• W3119781569 cites W3010518562 @default.
• W3119781569 cites W3017690924 @default.
• W3119781569 cites W3032600724 @default.
• W3119781569 cites W3035185084 @default.
• W3119781569 cites W3035334103 @default.
• W3119781569 cites W3036500399 @default.
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• W3119781569 cites W3080735488 @default.
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• W3119781569 doi "https://doi.org/10.1111/dgd.12708" @default.
• W3119781569 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7940568" @default.
• W3119781569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33423319" @default.
• W3119781569 hasPublicationYear "2021" @default.
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