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- W3119886325 abstract "Skin, the largest human organ, is colonized by billions of microorganisms, with a great variety (bacteria, fungi, viruses, protozoans), which adapted to the chemical and physical characteristics of the skin and formed the skin microbiome or microbiota. Staphylococcus epidermidis and other coagulase-negative staphylococci have been considered the main skin colonizers. With the advent of molecular technologies for microbial gene detection and identification, it became obvious that the germs growing technique detects only a small part of the total skin microorganisms. After gut, the most numerous microorganisms are located at the skin level. Regarding the skin microbiome, the bacterial species are the most abundant, being classified into four bacterial phyla: Actinobacteria, Bacteroidetes, Firmicutes and Proteobacteria. At present, there are few details regarding the description and function of non-bacterial commensal germs. At the skin level, a part of the microbial flora is common for all people, while another part is unique to each individual, this diversity being influenced by a series of factors such as skin anatomy, host-related factors, environmental factors etc. Skin microbiome has an essential role in protecting against invading pathogens and in educating our immune system, but under certain circumstances, when the equilibrium of this microbial community is disrupted, some skin commensal germs can become pathogens, causing a skin disease or even a systemic one. There are many unknown aspects regarding the skin microbiome ant its role in human health and pathology, which require further in-depth studies." @default.
- W3119886325 created "2021-01-18" @default.
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- W3119886325 date "2020-01-01" @default.
- W3119886325 modified "2023-09-25" @default.
- W3119886325 title "Skin microbiome and its role in human health and pathology" @default.
- W3119886325 doi "https://doi.org/10.26416/med.136.4.2020.3665" @default.
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