FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3119989757> ?p ?o ?g. }

• W3119989757 endingPage "316" @default.
• W3119989757 startingPage "316" @default.
• W3119989757 abstract "This patient presented with high-grade epidural disease (Bilsky grade 2 and 3) and underwent urgent surgical decompression with subsequent downgrading of epidural disease on imaging. 1 Pinkawa M. Spinal cord reirradiation-balancing benefit against risks. Int J Radiat Oncol Biol Phys. 2021; 109: 312-313 Abstract Full Text Full Text PDF PubMed Scopus (3) Google Scholar Postoperative spine stereotactic body radiation therapy (SBRT) experience has shown that a postoperative epidural Bilsky grade of 0 or 1 is a significant predictor of local control. 2 Al-Omair A. Masucci L. Masson-Cote L. et al. Surgical resection of epidural disease improves local control following postoperative spine stereotactic body radiotherapy. Neuro Oncol. 2013; 15: 1413-1419 Crossref PubMed Scopus (113) Google Scholar In the absence of biomarkers or next-generation molecular diagnostics we cannot determine with certainty which patients with oligometastatic disease will benefit from metastasis-directed treatment with SBRT. However, this is a young patient with oligometastatic disease, limited tumor burden, long disease-free interval, favorable histology, and life expectancy with potential future systemic options; as such, we would treat with SBRT to optimize local control. We would not offer conventional palliative external beam radiation therapy in this setting. 3 Chow E. van der Linden Y.M. Roos D. et al. Single versus multiple fractions of repeat radiation for painful bone metastases: A randomised, controlled, non-inferiority trial. Lancet Oncol. 2014; 15: 164-171 Abstract Full Text Full Text PDF PubMed Scopus (187) Google Scholar ,4 Myrehaug S. Sahgal A. Hayashi M. et al. Reirradiation spine stereotactic body radiation therapy for spinal metastases: A systematic review. J Neurosurg Spine. 2017; 27: 428-435 Crossref PubMed Scopus (74) Google Scholar Given the dearth of evidence using radiosensitizers, we would not recommend their use due to concerns about an increased risk of myelopathy, particularly in the context of reirradiation. Treatment volumes would include the entire extent of the pre- and postoperative disease and the adjacent anatomic segment, as per the evidence-based consensus contouring guidelines. 5 Redmond K.J. Robertson S. Lo S.S. et al. Consensus contouring guidelines for postoperative stereotactic body radiation therapy for metastatic solid tumor malignancies to the spine. Int J Radiat Oncol Biol Phys. 2017; 97: 64-74 Abstract Full Text Full Text PDF PubMed Scopus (63) Google Scholar Optimal dose in this setting is still unknown. We would treat with 24 Gy in 2 fractions or 35 Gy in 5 fractions, a prescription similar to that given for the intact vertebrae. In the setting of reirradiation, a total thecal sac maximum point EQD2 of approximately 70 Gy2/2 with a minimum time interval to reirradiation of at least 5 months has been suggested to be clinically safe. 6 Sahgal A. Ma L. Weinberg V. et al. Reirradiation human spinal cord tolerance for stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2012; 82: 107-116 Abstract Full Text Full Text PDF PubMed Scopus (164) Google Scholar" @default.
• W3119989757 created "2021-01-18" @default.
• W3119989757 creator A5012511065 @default.
• W3119989757 creator A5069530937 @default.
• W3119989757 date "2021-02-01" @default.
• W3119989757 modified "2023-09-27" @default.
• W3119989757 title "Postoperative Stereotactic Body Radiation Therapy, Then Observe" @default.
• W3119989757 cites W2026751464 @default.
• W3119989757 cites W2138156952 @default.
• W3119989757 cites W2171155897 @default.
• W3119989757 cites W2519947040 @default.
• W3119989757 cites W2734911387 @default.
• W3119989757 cites W3119766483 @default.
• W3119989757 doi "https://doi.org/10.1016/j.ijrobp.2019.09.020" @default.
• W3119989757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33422274" @default.
• W3119989757 hasPublicationYear "2021" @default.
• W3119989757 type Work @default.
• W3119989757 sameAs 3119989757 @default.
• W3119989757 citedByCount "0" @default.
• W3119989757 crossrefType "journal-article" @default.
• W3119989757 hasAuthorship W3119989757A5012511065 @default.
• W3119989757 hasAuthorship W3119989757A5069530937 @default.
• W3119989757 hasConcept C126838900 @default.
• W3119989757 hasConcept C141071460 @default.
• W3119989757 hasConcept C2779480328 @default.
• W3119989757 hasConcept C2780387249 @default.
• W3119989757 hasConcept C509974204 @default.
• W3119989757 hasConcept C71924100 @default.
• W3119989757 hasConceptScore W3119989757C126838900 @default.
• W3119989757 hasConceptScore W3119989757C141071460 @default.
• W3119989757 hasConceptScore W3119989757C2779480328 @default.
• W3119989757 hasConceptScore W3119989757C2780387249 @default.
• W3119989757 hasConceptScore W3119989757C509974204 @default.
• W3119989757 hasConceptScore W3119989757C71924100 @default.
• W3119989757 hasIssue "2" @default.
• W3119989757 hasLocation W31199897571 @default.
• W3119989757 hasOpenAccess W3119989757 @default.
• W3119989757 hasPrimaryLocation W31199897571 @default.
• W3119989757 hasRelatedWork W2002120878 @default.
• W3119989757 hasRelatedWork W2003938723 @default.
• W3119989757 hasRelatedWork W2047967234 @default.
• W3119989757 hasRelatedWork W2076264651 @default.
• W3119989757 hasRelatedWork W2118496982 @default.
• W3119989757 hasRelatedWork W2364998975 @default.
• W3119989757 hasRelatedWork W2439875401 @default.
• W3119989757 hasRelatedWork W4238867864 @default.
• W3119989757 hasRelatedWork W2519357708 @default.
• W3119989757 hasRelatedWork W2525756941 @default.
• W3119989757 hasVolume "109" @default.
• W3119989757 isParatext "false" @default.
• W3119989757 isRetracted "false" @default.
• W3119989757 magId "3119989757" @default.
• W3119989757 workType "article" @default.