FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120071845> ?p ?o ?g. }

• W3120071845 abstract "The role of Ly49 + CD8 T-cells in the immune system is not clear. Previously, several papers suggested Ly49 + CD8 T-cells as immunosuppressors, while multiple studies also suggested their role as potent participants of the immune response. The mechanism of Ly49 expression on CD8 T-cells is also not clear. We investigated phenotype, functions, and regulation of Ly49 expression on murine CD8 T-cells in both normal state and during LCMV infection. CD8 T-cells express different Ly49 receptors compared with NK-cells. In intact mice, Ly49 + CD8 T-cells have a phenotype similar to resting central memory CD8 T-cells and do not show impaired proliferation and cytokine production. Conventional CD8 T-cells upregulate Ly49 receptors during TCR-induced stimulation, and IL-2, as well as IL-15, affect it. At the same time, Ly49 + CD8 T-cells change the Ly49 expression profile dramatically upon re-stimulation downregulating inhibitory and upregulating activating Ly49 receptors. We observed the expression of Ly49 receptors on the virus-specific CD8 T-cells during LCMV infection, especially marked in the early stages, and participation of Ly49 + CD8 T-cells in the anti-viral response. Thus, CD8 T-cells acquire Ly49 receptors during the T-cell activation and show dynamic regulation of Ly49 receptors during stimulation." @default.
• W3120071845 created "2021-01-18" @default.
• W3120071845 creator A5001888691 @default.
• W3120071845 creator A5005578291 @default.
• W3120071845 creator A5026440265 @default.
• W3120071845 creator A5038851564 @default.
• W3120071845 creator A5051125527 @default.
• W3120071845 creator A5059107772 @default.
• W3120071845 creator A5060272973 @default.
• W3120071845 creator A5068485625 @default.
• W3120071845 date "2021-01-07" @default.
• W3120071845 modified "2023-10-15" @default.
• W3120071845 title "Functional Characterization of Ly49+CD8 T-Cells in Both Normal Condition and During Anti-Viral Response" @default.
• W3120071845 cites W1483517797 @default.
• W3120071845 cites W1484345440 @default.
• W3120071845 cites W1515446407 @default.
• W3120071845 cites W1552314410 @default.
• W3120071845 cites W1568984819 @default.
• W3120071845 cites W1571334635 @default.
• W3120071845 cites W1575885906 @default.
• W3120071845 cites W1612595544 @default.
• W3120071845 cites W1631454955 @default.
• W3120071845 cites W1870969965 @default.
• W3120071845 cites W1908347506 @default.
• W3120071845 cites W1934719640 @default.
• W3120071845 cites W1965026817 @default.
• W3120071845 cites W1973486131 @default.
• W3120071845 cites W1978498621 @default.
• W3120071845 cites W1979424337 @default.
• W3120071845 cites W1986498374 @default.
• W3120071845 cites W2007172280 @default.
• W3120071845 cites W2029541199 @default.
• W3120071845 cites W2033176510 @default.
• W3120071845 cites W2037133606 @default.
• W3120071845 cites W2051032723 @default.
• W3120071845 cites W2053953648 @default.
• W3120071845 cites W2059068052 @default.
• W3120071845 cites W2059448923 @default.
• W3120071845 cites W2068517086 @default.
• W3120071845 cites W2071732726 @default.
• W3120071845 cites W2080439606 @default.
• W3120071845 cites W2099465341 @default.
• W3120071845 cites W2100201151 @default.
• W3120071845 cites W2104595884 @default.
• W3120071845 cites W2127805611 @default.
• W3120071845 cites W2127999782 @default.
• W3120071845 cites W2133655297 @default.
• W3120071845 cites W2146266775 @default.
• W3120071845 cites W2157597649 @default.
• W3120071845 cites W2159441277 @default.
• W3120071845 cites W2165112338 @default.
• W3120071845 cites W2168928173 @default.
• W3120071845 cites W2553760426 @default.
• W3120071845 cites W2764187574 @default.
• W3120071845 cites W2896230562 @default.
• W3120071845 cites W2955871366 @default.
• W3120071845 cites W2966549733 @default.
• W3120071845 cites W2985610874 @default.
• W3120071845 doi "https://doi.org/10.3389/fimmu.2020.602783" @default.
• W3120071845 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7817614" @default.
• W3120071845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33488602" @default.
• W3120071845 hasPublicationYear "2021" @default.
• W3120071845 type Work @default.
• W3120071845 sameAs 3120071845 @default.
• W3120071845 citedByCount "3" @default.
• W3120071845 countsByYear W31200718452021 @default.
• W3120071845 countsByYear W31200718452022 @default.
• W3120071845 countsByYear W31200718452023 @default.
• W3120071845 crossrefType "journal-article" @default.
• W3120071845 hasAuthorship W3120071845A5001888691 @default.
• W3120071845 hasAuthorship W3120071845A5005578291 @default.
• W3120071845 hasAuthorship W3120071845A5026440265 @default.
• W3120071845 hasAuthorship W3120071845A5038851564 @default.
• W3120071845 hasAuthorship W3120071845A5051125527 @default.
• W3120071845 hasAuthorship W3120071845A5059107772 @default.
• W3120071845 hasAuthorship W3120071845A5060272973 @default.
• W3120071845 hasAuthorship W3120071845A5068485625 @default.
• W3120071845 hasBestOaLocation W31200718451 @default.
• W3120071845 hasConcept C120642132 @default.
• W3120071845 hasConcept C129374314 @default.
• W3120071845 hasConcept C154317977 @default.
• W3120071845 hasConcept C167672396 @default.
• W3120071845 hasConcept C170493617 @default.
• W3120071845 hasConcept C202751555 @default.
• W3120071845 hasConcept C203014093 @default.
• W3120071845 hasConcept C2776090121 @default.
• W3120071845 hasConcept C2778690821 @default.
• W3120071845 hasConcept C55493867 @default.
• W3120071845 hasConcept C79484868 @default.
• W3120071845 hasConcept C86803240 @default.
• W3120071845 hasConcept C8891405 @default.
• W3120071845 hasConcept C95444343 @default.
• W3120071845 hasConceptScore W3120071845C120642132 @default.
• W3120071845 hasConceptScore W3120071845C129374314 @default.
• W3120071845 hasConceptScore W3120071845C154317977 @default.
• W3120071845 hasConceptScore W3120071845C167672396 @default.
• W3120071845 hasConceptScore W3120071845C170493617 @default.
• W3120071845 hasConceptScore W3120071845C202751555 @default.
• W3120071845 hasConceptScore W3120071845C203014093 @default.
• W3120071845 hasConceptScore W3120071845C2776090121 @default.

• next