FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120147496> ?p ?o ?g. }

• W3120147496 abstract "Harmful environmental sounds are a prevailing source of chronic hearing impairments, including noise induced hearing loss, hyperacusis, or tinnitus. How these symptoms are related to pathophysiological damage to the sensory receptor epithelia and its effects along the auditory pathway, have been documented in numerous studies. An open question concerns the temporal evolution of maladaptive changes after damage and their manifestation in the balance of thalamocortical and corticocortical input to the auditory cortex (ACx). To address these issues, we investigated the loci of plastic reorganizations across the tonotopic axis of the auditory cortex of male Mongolian gerbils ( Meriones unguiculatus ) acutely after a sound trauma and after several weeks. We used a residual current-source density analysis to dissociate adaptations of intracolumnar input and horizontally relayed corticocortical input to synaptic populations across cortical layers in ACx. A pure tone-based sound trauma caused acute changes of subcortical inputs and corticocortical inputs at all tonotopic regions, particularly showing a broad reduction of tone-evoked inputs at tonotopic regions around the trauma frequency. At other cortical sites, the overall columnar activity acutely decreased, while relative contributions of lateral corticocortical inputs increased. After 4–6 weeks, cortical activity in response to the altered sensory inputs showed a general increase of local thalamocortical input reaching levels higher than before the trauma. Hence, our results suggest a detailed mechanism for overcompensation of altered frequency input in the auditory cortex that relies on a changing balance of thalamocortical and intracortical input and along the frequency gradient of the cortical tonotopic map." @default.
• W3120147496 created "2021-01-18" @default.
• W3120147496 creator A5001136712 @default.
• W3120147496 creator A5003210328 @default.
• W3120147496 creator A5014313028 @default.
• W3120147496 creator A5026690582 @default.
• W3120147496 creator A5051256315 @default.
• W3120147496 creator A5062539159 @default.
• W3120147496 creator A5087402600 @default.
• W3120147496 date "2021-01-05" @default.
• W3120147496 modified "2023-09-27" @default.
• W3120147496 title "Acute and Long-Term Circuit-Level Effects in the Auditory Cortex After Sound Trauma" @default.
• W3120147496 cites W1893259010 @default.
• W3120147496 cites W1969361316 @default.
• W3120147496 cites W1969491530 @default.
• W3120147496 cites W1969827432 @default.
• W3120147496 cites W1978441796 @default.
• W3120147496 cites W1985946645 @default.
• W3120147496 cites W1997387173 @default.
• W3120147496 cites W1999109983 @default.
• W3120147496 cites W2001110658 @default.
• W3120147496 cites W2003052230 @default.
• W3120147496 cites W2009775184 @default.
• W3120147496 cites W2009847261 @default.
• W3120147496 cites W2014764196 @default.
• W3120147496 cites W2021255606 @default.
• W3120147496 cites W2021955561 @default.
• W3120147496 cites W2036483999 @default.
• W3120147496 cites W2038262310 @default.
• W3120147496 cites W2041918412 @default.
• W3120147496 cites W2050022878 @default.
• W3120147496 cites W2056829537 @default.
• W3120147496 cites W2062192993 @default.
• W3120147496 cites W2066389227 @default.
• W3120147496 cites W2068334533 @default.
• W3120147496 cites W2075353997 @default.
• W3120147496 cites W2080811299 @default.
• W3120147496 cites W2084059718 @default.
• W3120147496 cites W2085393729 @default.
• W3120147496 cites W2091194823 @default.
• W3120147496 cites W2097853513 @default.
• W3120147496 cites W2111736228 @default.
• W3120147496 cites W2148398429 @default.
• W3120147496 cites W2149736796 @default.
• W3120147496 cites W2150405052 @default.
• W3120147496 cites W2154481506 @default.
• W3120147496 cites W2158592437 @default.
• W3120147496 cites W2165393423 @default.
• W3120147496 cites W2171516196 @default.
• W3120147496 cites W2210264310 @default.
• W3120147496 cites W2289964435 @default.
• W3120147496 cites W2406702197 @default.
• W3120147496 cites W2467777966 @default.
• W3120147496 cites W2510828140 @default.
• W3120147496 cites W2543882133 @default.
• W3120147496 cites W2599617789 @default.
• W3120147496 cites W2609322989 @default.
• W3120147496 cites W2766608784 @default.
• W3120147496 cites W2792330332 @default.
• W3120147496 cites W2797571794 @default.
• W3120147496 cites W2809620273 @default.
• W3120147496 cites W2888467690 @default.
• W3120147496 cites W2963193428 @default.
• W3120147496 cites W2984828548 @default.
• W3120147496 cites W3009705462 @default.
• W3120147496 cites W3011836679 @default.
• W3120147496 cites W3039806679 @default.
• W3120147496 cites W3042217284 @default.
• W3120147496 cites W4246176420 @default.
• W3120147496 cites W4249561229 @default.
• W3120147496 cites W644321259 @default.
• W3120147496 cites W2569500008 @default.
• W3120147496 doi "https://doi.org/10.3389/fnins.2020.598406" @default.
• W3120147496 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7813782" @default.
• W3120147496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33469416" @default.
• W3120147496 hasPublicationYear "2021" @default.
• W3120147496 type Work @default.
• W3120147496 sameAs 3120147496 @default.
• W3120147496 citedByCount "9" @default.
• W3120147496 countsByYear W31201474962021 @default.
• W3120147496 countsByYear W31201474962022 @default.
• W3120147496 countsByYear W31201474962023 @default.
• W3120147496 crossrefType "journal-article" @default.
• W3120147496 hasAuthorship W3120147496A5001136712 @default.
• W3120147496 hasAuthorship W3120147496A5003210328 @default.
• W3120147496 hasAuthorship W3120147496A5014313028 @default.
• W3120147496 hasAuthorship W3120147496A5026690582 @default.
• W3120147496 hasAuthorship W3120147496A5051256315 @default.
• W3120147496 hasAuthorship W3120147496A5062539159 @default.
• W3120147496 hasAuthorship W3120147496A5087402600 @default.
• W3120147496 hasBestOaLocation W31201474961 @default.
• W3120147496 hasConcept C121332964 @default.
• W3120147496 hasConcept C15744967 @default.
• W3120147496 hasConcept C169760540 @default.
• W3120147496 hasConcept C203718221 @default.
• W3120147496 hasConcept C24890656 @default.
• W3120147496 hasConcept C2776532659 @default.
• W3120147496 hasConcept C2776992516 @default.
• W3120147496 hasConcept C2777348757 @default.
• W3120147496 hasConcept C2780297895 @default.

• next