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• W3120148921 abstract "Aedes aegypti, as one of the vectors transmitting several arboviruses, is the main target in mosquito control programs. Permethrin is used to control mosquitoes and Aedes aegypti get exposed due to its overuse and are now resistant. The increasing percentage of permethrin resistant Aedes aegypti has become an important issue around the world and the potential influence on vectorial capacity needs to be studied. Here we selected a permethrin resistant (p-s) Aedes aegypti population from a wild Florida population and confirmed the resistance ratio to its parental population. We used allele-specific PCR genotyping of the V1016I and F1534C sites in the sodium channel gene to map mutations responsible for the resistance. Two important factors, survival rate and vector competence, that impact vectorial capacity were checked. Results indicated the p-s population had 20 times more resistance to permethrin based on LD50 compared to the parental population. In the genotyping study, the p-s population had more homozygous mutations in both mutant sites of the sodium channel gene. The p-s adults survived longer and had a higher dissemination rate for dengue virus than the parental population. These results suggest that highly permethrin resistant Aedes aegypti populations might affect the vectorial capacity, moreover, resistance increased the survival time and vector competence, which should be of concern in areas where permethrin is applied." @default.
• W3120148921 created "2021-01-18" @default.
• W3120148921 creator A5037277689 @default.
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• W3120148921 date "2021-01-14" @default.
• W3120148921 modified "2023-10-17" @default.
• W3120148921 title "Permethrin Resistance in Aedes aegypti Affects Aspects of Vectorial Capacity" @default.
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• W3120148921 doi "https://doi.org/10.3390/insects12010071" @default.
• W3120148921 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7830706" @default.
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• W3120148921 hasPublicationYear "2021" @default.
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