FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120221452> ?p ?o ?g. }

• W3120221452 endingPage "1470" @default.
• W3120221452 startingPage "1463" @default.
• W3120221452 abstract "Background Nutritional status and tumor markers are important prognostic indicators for surgical decisions in pancreatic carcinoma. This study aimed to stratify the probability of surviving pancreatic carcinoma based on systematically chosen nonanatomic biomarkers. Methods We included 187 consecutive patients that underwent surgical resections for pancreatic carcinoma. We performed multivariable analyses to evaluate prognostic indicators, including 4 blood-test indexes: the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, prognostic nutritional index, and the modified Glasgow prognostic score; and 4 body-composition indexes: the normalized total psoas muscle area, the normalized total elector spine muscle area, the psoas muscle computed tomography value, and the elector spine muscle computed tomography value. Results Poor survival was associated with 2 independent risk factors: neutrophil-to-lymphocyte ratio ≥3.0 (hazard ratio, 1.54) and prognostic nutritional index <36 (hazard ratio, 1.60), and with high carbohydrate antigen 19-9 levels (≥37 IU/mL). The 2 indexes were not significantly associated with clinicopathological factors, including carbohydrate antigen 19-9. Patients with no risk factors had significantly better survival than those with 1 (P = .007) or 2 risk factors (P = .001), and survival was similar in the latter 2 groups (P = .253). A presurgical nonanatomic scoring system (range, 0−2) was constructed: 0 points for no risk factors, 1 point for 1 or 2 nutritional risk factors, and 1 point for carbohydrate antigen 19-9 ≥37 IU/mL. Survival rate at 3 years decreased with increasing scores (76% for score 0, 42% for score 1, and 21% for score 2; all P < .05). Conclusion Neutrophil-to-lymphocyte ratio and prognostic nutritional index were independent prognostic risk factors in pancreatic carcinoma and integrating these indexes with carbohydrate antigen 19-9 levels could successfully stratify survival. Nutritional status and tumor markers are important prognostic indicators for surgical decisions in pancreatic carcinoma. This study aimed to stratify the probability of surviving pancreatic carcinoma based on systematically chosen nonanatomic biomarkers. We included 187 consecutive patients that underwent surgical resections for pancreatic carcinoma. We performed multivariable analyses to evaluate prognostic indicators, including 4 blood-test indexes: the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, prognostic nutritional index, and the modified Glasgow prognostic score; and 4 body-composition indexes: the normalized total psoas muscle area, the normalized total elector spine muscle area, the psoas muscle computed tomography value, and the elector spine muscle computed tomography value. Poor survival was associated with 2 independent risk factors: neutrophil-to-lymphocyte ratio ≥3.0 (hazard ratio, 1.54) and prognostic nutritional index <36 (hazard ratio, 1.60), and with high carbohydrate antigen 19-9 levels (≥37 IU/mL). The 2 indexes were not significantly associated with clinicopathological factors, including carbohydrate antigen 19-9. Patients with no risk factors had significantly better survival than those with 1 (P = .007) or 2 risk factors (P = .001), and survival was similar in the latter 2 groups (P = .253). A presurgical nonanatomic scoring system (range, 0−2) was constructed: 0 points for no risk factors, 1 point for 1 or 2 nutritional risk factors, and 1 point for carbohydrate antigen 19-9 ≥37 IU/mL. Survival rate at 3 years decreased with increasing scores (76% for score 0, 42% for score 1, and 21% for score 2; all P < .05). Neutrophil-to-lymphocyte ratio and prognostic nutritional index were independent prognostic risk factors in pancreatic carcinoma and integrating these indexes with carbohydrate antigen 19-9 levels could successfully stratify survival." @default.
• W3120221452 created "2021-01-18" @default.
• W3120221452 creator A5011048888 @default.
• W3120221452 creator A5011051302 @default.
• W3120221452 creator A5026188526 @default.
• W3120221452 creator A5052829488 @default.
• W3120221452 creator A5053193095 @default.
• W3120221452 creator A5054548406 @default.
• W3120221452 creator A5060579946 @default.
• W3120221452 creator A5060818759 @default.
• W3120221452 creator A5081840313 @default.
• W3120221452 date "2021-06-01" @default.
• W3120221452 modified "2023-10-18" @default.
• W3120221452 title "A presurgical prognostic stratification based on nutritional assessment and carbohydrate antigen 19-9 in pancreatic carcinoma: An approach with nonanatomic biomarkers" @default.
• W3120221452 cites W1990882666 @default.
• W3120221452 cites W2008014332 @default.
• W3120221452 cites W2011394566 @default.
• W3120221452 cites W2018997491 @default.
• W3120221452 cites W2034267351 @default.
• W3120221452 cites W2096998881 @default.
• W3120221452 cites W2101398993 @default.
• W3120221452 cites W2104357394 @default.
• W3120221452 cites W2117853299 @default.
• W3120221452 cites W2119490885 @default.
• W3120221452 cites W2129197203 @default.
• W3120221452 cites W2136339108 @default.
• W3120221452 cites W2268241669 @default.
• W3120221452 cites W2275716355 @default.
• W3120221452 cites W2341916527 @default.
• W3120221452 cites W2411143367 @default.
• W3120221452 cites W2412717755 @default.
• W3120221452 cites W2525574652 @default.
• W3120221452 cites W2560616440 @default.
• W3120221452 cites W2767643188 @default.
• W3120221452 cites W2891402528 @default.
• W3120221452 cites W2897709693 @default.
• W3120221452 cites W2898370617 @default.
• W3120221452 cites W2912510891 @default.
• W3120221452 cites W2945520258 @default.
• W3120221452 cites W3002335380 @default.
• W3120221452 cites W3011169222 @default.
• W3120221452 cites W935911064 @default.
• W3120221452 doi "https://doi.org/10.1016/j.surg.2020.11.035" @default.
• W3120221452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33423799" @default.
• W3120221452 hasPublicationYear "2021" @default.
• W3120221452 type Work @default.
• W3120221452 sameAs 3120221452 @default.
• W3120221452 citedByCount "5" @default.
• W3120221452 countsByYear W31202214522021 @default.
• W3120221452 countsByYear W31202214522022 @default.
• W3120221452 countsByYear W31202214522023 @default.
• W3120221452 crossrefType "journal-article" @default.
• W3120221452 hasAuthorship W3120221452A5011048888 @default.
• W3120221452 hasAuthorship W3120221452A5011051302 @default.
• W3120221452 hasAuthorship W3120221452A5026188526 @default.
• W3120221452 hasAuthorship W3120221452A5052829488 @default.
• W3120221452 hasAuthorship W3120221452A5053193095 @default.
• W3120221452 hasAuthorship W3120221452A5054548406 @default.
• W3120221452 hasAuthorship W3120221452A5060579946 @default.
• W3120221452 hasAuthorship W3120221452A5060818759 @default.
• W3120221452 hasAuthorship W3120221452A5081840313 @default.
• W3120221452 hasConcept C126322002 @default.
• W3120221452 hasConcept C141071460 @default.
• W3120221452 hasConcept C143998085 @default.
• W3120221452 hasConcept C207103383 @default.
• W3120221452 hasConcept C2777546739 @default.
• W3120221452 hasConcept C2780221984 @default.
• W3120221452 hasConcept C44249647 @default.
• W3120221452 hasConcept C71924100 @default.
• W3120221452 hasConcept C90924648 @default.
• W3120221452 hasConceptScore W3120221452C126322002 @default.
• W3120221452 hasConceptScore W3120221452C141071460 @default.
• W3120221452 hasConceptScore W3120221452C143998085 @default.
• W3120221452 hasConceptScore W3120221452C207103383 @default.
• W3120221452 hasConceptScore W3120221452C2777546739 @default.
• W3120221452 hasConceptScore W3120221452C2780221984 @default.
• W3120221452 hasConceptScore W3120221452C44249647 @default.
• W3120221452 hasConceptScore W3120221452C71924100 @default.
• W3120221452 hasConceptScore W3120221452C90924648 @default.
• W3120221452 hasIssue "6" @default.
• W3120221452 hasLocation W31202214521 @default.
• W3120221452 hasOpenAccess W3120221452 @default.
• W3120221452 hasPrimaryLocation W31202214521 @default.
• W3120221452 hasRelatedWork W1900595920 @default.
• W3120221452 hasRelatedWork W2003938723 @default.
• W3120221452 hasRelatedWork W2047967234 @default.
• W3120221452 hasRelatedWork W2074568790 @default.
• W3120221452 hasRelatedWork W2114624491 @default.
• W3120221452 hasRelatedWork W2118496982 @default.
• W3120221452 hasRelatedWork W2194631636 @default.
• W3120221452 hasRelatedWork W2410041842 @default.
• W3120221452 hasRelatedWork W2439875401 @default.
• W3120221452 hasRelatedWork W2889691785 @default.
• W3120221452 hasVolume "169" @default.
• W3120221452 isParatext "false" @default.
• W3120221452 isRetracted "false" @default.
• W3120221452 magId "3120221452" @default.
• W3120221452 workType "article" @default.