Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120236189> ?p ?o ?g. }
- W3120236189 endingPage "262" @default.
- W3120236189 startingPage "256" @default.
- W3120236189 abstract "The prevalently used LC–MS/MS methods for the simultaneous determination of synthetic phenol antioxidants (SPAs) and relevant metabolites suffer from a serious drawback of low sensitivity for 2,6-di-tert-butyl-4-hydroxytoluene (BHT) and a common issue of background contamination, which hampers the simple and accurate detection of these substances at trace levels in environmental samples. In this study, we developed an improved LC–MS/MS method for the simultaneous determination of eight SPAs and four relevant metabolites, including BHT. By use of atmospheric pressure chemical ionization (APCI), the sensitivity of BHT in the LC–MS/MS was enhanced approximately 260 times versus results obtained by using electrospray ionization (ESI), which allowed the analysis of BHT up to 1.1 ng/g in indoor dust and 0.06 ng/g in human plasma. Similarly, the sensitivity of 2,4,6-tri-tert-butylphenol and 2,6-di-tert-butyl-4-sec-butylphenol was also enhanced with APCI, which avoided their separate analysis by GC–MS. By installation of a C18 column after the eluent mixer and before the injector as a trap column, the target analytes leached out from the LC system were eluted at a much later retention time than those in the samples, which resulted in complete elimination of the instrumental background contamination. These improvements enable the method to be well applied to the real samples." @default.
- W3120236189 created "2021-01-18" @default.
- W3120236189 creator A5013604656 @default.
- W3120236189 creator A5019681478 @default.
- W3120236189 creator A5023874610 @default.
- W3120236189 creator A5027188224 @default.
- W3120236189 creator A5054912723 @default.
- W3120236189 creator A5074150520 @default.
- W3120236189 creator A5084405248 @default.
- W3120236189 date "2021-01-05" @default.
- W3120236189 modified "2023-10-14" @default.
- W3120236189 title "Improved LC–MS/MS Method for the Simultaneous Determination of Synthetic Phenol Antioxidants and Relevant Metabolites Making Use of Atmospheric Pressure Chemical Ionization and a Trap Column" @default.
- W3120236189 cites W1971188018 @default.
- W3120236189 cites W197238146 @default.
- W3120236189 cites W1974894863 @default.
- W3120236189 cites W1977707385 @default.
- W3120236189 cites W1979504600 @default.
- W3120236189 cites W1996784422 @default.
- W3120236189 cites W1998947314 @default.
- W3120236189 cites W2018203935 @default.
- W3120236189 cites W2027364439 @default.
- W3120236189 cites W2042138057 @default.
- W3120236189 cites W2045360939 @default.
- W3120236189 cites W2066136874 @default.
- W3120236189 cites W2067923517 @default.
- W3120236189 cites W2090793327 @default.
- W3120236189 cites W2121251778 @default.
- W3120236189 cites W2145568838 @default.
- W3120236189 cites W2146034259 @default.
- W3120236189 cites W2161113186 @default.
- W3120236189 cites W2186871636 @default.
- W3120236189 cites W2249640667 @default.
- W3120236189 cites W2318842524 @default.
- W3120236189 cites W2321431979 @default.
- W3120236189 cites W2569336775 @default.
- W3120236189 cites W2763233050 @default.
- W3120236189 cites W2769733121 @default.
- W3120236189 cites W2769889484 @default.
- W3120236189 cites W2772492348 @default.
- W3120236189 cites W2800589591 @default.
- W3120236189 cites W2801303920 @default.
- W3120236189 cites W2810178673 @default.
- W3120236189 cites W2885607084 @default.
- W3120236189 cites W2900154854 @default.
- W3120236189 cites W2901424666 @default.
- W3120236189 cites W2903034648 @default.
- W3120236189 cites W2930643771 @default.
- W3120236189 cites W2940884968 @default.
- W3120236189 cites W2980563762 @default.
- W3120236189 cites W2987363577 @default.
- W3120236189 cites W2997509370 @default.
- W3120236189 cites W3007894803 @default.
- W3120236189 cites W3084753814 @default.
- W3120236189 cites W4251496978 @default.
- W3120236189 cites W583266851 @default.
- W3120236189 doi "https://doi.org/10.1021/acs.estlett.0c01013" @default.
- W3120236189 hasPublicationYear "2021" @default.
- W3120236189 type Work @default.
- W3120236189 sameAs 3120236189 @default.
- W3120236189 citedByCount "7" @default.
- W3120236189 countsByYear W31202361892021 @default.
- W3120236189 countsByYear W31202361892023 @default.
- W3120236189 crossrefType "journal-article" @default.
- W3120236189 hasAuthorship W3120236189A5013604656 @default.
- W3120236189 hasAuthorship W3120236189A5019681478 @default.
- W3120236189 hasAuthorship W3120236189A5023874610 @default.
- W3120236189 hasAuthorship W3120236189A5027188224 @default.
- W3120236189 hasAuthorship W3120236189A5054912723 @default.
- W3120236189 hasAuthorship W3120236189A5074150520 @default.
- W3120236189 hasAuthorship W3120236189A5084405248 @default.
- W3120236189 hasConcept C10390740 @default.
- W3120236189 hasConcept C113196181 @default.
- W3120236189 hasConcept C145148216 @default.
- W3120236189 hasConcept C148065180 @default.
- W3120236189 hasConcept C162356407 @default.
- W3120236189 hasConcept C178790620 @default.
- W3120236189 hasConcept C185592680 @default.
- W3120236189 hasConcept C194451485 @default.
- W3120236189 hasConcept C198291218 @default.
- W3120236189 hasConcept C2777702071 @default.
- W3120236189 hasConcept C2778004101 @default.
- W3120236189 hasConcept C2779661893 @default.
- W3120236189 hasConcept C40684141 @default.
- W3120236189 hasConcept C43617362 @default.
- W3120236189 hasConcept C51884965 @default.
- W3120236189 hasConcept C64489805 @default.
- W3120236189 hasConcept C73826308 @default.
- W3120236189 hasConceptScore W3120236189C10390740 @default.
- W3120236189 hasConceptScore W3120236189C113196181 @default.
- W3120236189 hasConceptScore W3120236189C145148216 @default.
- W3120236189 hasConceptScore W3120236189C148065180 @default.
- W3120236189 hasConceptScore W3120236189C162356407 @default.
- W3120236189 hasConceptScore W3120236189C178790620 @default.
- W3120236189 hasConceptScore W3120236189C185592680 @default.
- W3120236189 hasConceptScore W3120236189C194451485 @default.
- W3120236189 hasConceptScore W3120236189C198291218 @default.
- W3120236189 hasConceptScore W3120236189C2777702071 @default.
- W3120236189 hasConceptScore W3120236189C2778004101 @default.