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- W3120254416 endingPage "374" @default.
- W3120254416 startingPage "343" @default.
- W3120254416 abstract "Interest in 89Zr stems from the excellent image quality reported in both preclinical and clinical studies, but also from the ease, efficiency, and reproducibility of the bioconjugation chemistry and radio chemistry required to make 89Zr-labelled radiotracers. Other advantages include the low cost of production, automated isolation from the cyclotron target material (usually solid 89Y foils), and the possibility to ship stock radionuclide solutions across continents. This chapter explores some of the fundamental properties of zirconium in aqueous environments, as well as the production, chemistry, and radiochemistry associated with the synthesis of 89Zr-based radiotracers. It explores the production, chemistry, and radiochemistry of zirconium-89 for PET, but it is also worth mentioning that zirconium-97 is a potent β- emitter. The chemistry of Zr4+ ions is dominated by the fact that the ion has a very high charge-to-size ratio." @default.
- W3120254416 created "2021-01-18" @default.
- W3120254416 creator A5014626023 @default.
- W3120254416 date "2020-12-21" @default.
- W3120254416 modified "2023-10-18" @default.
- W3120254416 title "The Radiochemistry of Zirconium" @default.
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