FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120261188> ?p ?o ?g. }

• W3120261188 abstract "Background: Inhalational anesthetic-induced burst suppression (BS) is classically considered a bilaterally synchronous rhythm. However, local asynchrony has been predicted in theoretical studies and reported in patients with pre-existing focal pathology. Method: We used high-speed widefield calcium imaging to study the spatiotemporal dynamics of isoflurane-induced BS in rats. Results: We found that isoflurane-induced BS is not a globally synchronous rhythm. In the neocortex, neural activity first emerged in a spatially shifting, variably localized focus. Subsequent propagation across the whole cortex was rapid, typically within &lt;100 milliseconds, giving the superficial resemblance to global synchrony. Neural activity remained locally asynchronous during the bursts, forming complex recurrent propagating waves. Despite propagation variability, spatial sequences of burst propagation were largely preserved between the hemispheres, and neural activity was highly correlated between the homotopic areas. The critical role of the thalamus in cortical burst initiation was demonstrated by using unilateral thalamic tetrodotoxin injection. Conclusion: The classical impression that anesthetics-induced BS is a state of global brain synchrony is inaccurate. Bursts are a series of shifting local cortical events facilitated by thalamic projection that unfold as rapid, bilaterally asynchronous propagating waves." @default.
• W3120261188 created "2021-01-18" @default.
• W3120261188 creator A5003937466 @default.
• W3120261188 creator A5023623878 @default.
• W3120261188 creator A5033668915 @default.
• W3120261188 creator A5038851564 @default.
• W3120261188 creator A5040727973 @default.
• W3120261188 creator A5041169358 @default.
• W3120261188 creator A5046589830 @default.
• W3120261188 creator A5049145213 @default.
• W3120261188 creator A5050155202 @default.
• W3120261188 creator A5058150411 @default.
• W3120261188 creator A5062604671 @default.
• W3120261188 creator A5074141895 @default.
• W3120261188 creator A5079609871 @default.
• W3120261188 creator A5089952129 @default.
• W3120261188 creator A5090263544 @default.
• W3120261188 date "2021-01-12" @default.
• W3120261188 modified "2023-10-18" @default.
• W3120261188 title "Isoflurane-Induced Burst Suppression Is a Thalamus-Modulated, Focal-Onset Rhythm With Persistent Local Asynchrony and Variable Propagation Patterns in Rats" @default.
• W3120261188 cites W1541419413 @default.
• W3120261188 cites W1918978841 @default.
• W3120261188 cites W1923614344 @default.
• W3120261188 cites W1950544107 @default.
• W3120261188 cites W1966692467 @default.
• W3120261188 cites W1979041511 @default.
• W3120261188 cites W1981858635 @default.
• W3120261188 cites W1988881714 @default.
• W3120261188 cites W1990326404 @default.
• W3120261188 cites W1999423218 @default.
• W3120261188 cites W1999548395 @default.
• W3120261188 cites W2001631404 @default.
• W3120261188 cites W2003176741 @default.
• W3120261188 cites W2005019073 @default.
• W3120261188 cites W2006216368 @default.
• W3120261188 cites W2009606909 @default.
• W3120261188 cites W2010260992 @default.
• W3120261188 cites W2010838484 @default.
• W3120261188 cites W2015193381 @default.
• W3120261188 cites W2019684708 @default.
• W3120261188 cites W2023439184 @default.
• W3120261188 cites W2044547567 @default.
• W3120261188 cites W2044670283 @default.
• W3120261188 cites W2051406701 @default.
• W3120261188 cites W2077903532 @default.
• W3120261188 cites W2078214227 @default.
• W3120261188 cites W2080481491 @default.
• W3120261188 cites W2091191244 @default.
• W3120261188 cites W2099211886 @default.
• W3120261188 cites W2099878046 @default.
• W3120261188 cites W2101103067 @default.
• W3120261188 cites W2103288639 @default.
• W3120261188 cites W2110184874 @default.
• W3120261188 cites W2117469172 @default.
• W3120261188 cites W2118636975 @default.
• W3120261188 cites W2120606872 @default.
• W3120261188 cites W2124894330 @default.
• W3120261188 cites W2125592251 @default.
• W3120261188 cites W2133808276 @default.
• W3120261188 cites W2135583342 @default.
• W3120261188 cites W2138878199 @default.
• W3120261188 cites W2147648658 @default.
• W3120261188 cites W2153204292 @default.
• W3120261188 cites W2157032247 @default.
• W3120261188 cites W2168126101 @default.
• W3120261188 cites W2171332611 @default.
• W3120261188 cites W2255398506 @default.
• W3120261188 cites W2319172225 @default.
• W3120261188 cites W2410433134 @default.
• W3120261188 cites W2473321490 @default.
• W3120261188 cites W2473477790 @default.
• W3120261188 cites W2600881276 @default.
• W3120261188 cites W2782858624 @default.
• W3120261188 cites W2912852742 @default.
• W3120261188 cites W2969500343 @default.
• W3120261188 cites W3012706327 @default.
• W3120261188 cites W3016619206 @default.
• W3120261188 cites W3036538926 @default.
• W3120261188 cites W4254465866 @default.
• W3120261188 cites W4295831928 @default.
• W3120261188 doi "https://doi.org/10.3389/fnsys.2020.599781" @default.
• W3120261188 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7835516" @default.
• W3120261188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33510621" @default.
• W3120261188 hasPublicationYear "2021" @default.
• W3120261188 type Work @default.
• W3120261188 sameAs 3120261188 @default.
• W3120261188 citedByCount "8" @default.
• W3120261188 countsByYear W31202611882021 @default.
• W3120261188 countsByYear W31202611882022 @default.
• W3120261188 countsByYear W31202611882023 @default.
• W3120261188 crossrefType "journal-article" @default.
• W3120261188 hasAuthorship W3120261188A5003937466 @default.
• W3120261188 hasAuthorship W3120261188A5023623878 @default.
• W3120261188 hasAuthorship W3120261188A5033668915 @default.
• W3120261188 hasAuthorship W3120261188A5038851564 @default.
• W3120261188 hasAuthorship W3120261188A5040727973 @default.
• W3120261188 hasAuthorship W3120261188A5041169358 @default.
• W3120261188 hasAuthorship W3120261188A5046589830 @default.
• W3120261188 hasAuthorship W3120261188A5049145213 @default.
• W3120261188 hasAuthorship W3120261188A5050155202 @default.

• next