Matches in SemOpenAlex for { <https://semopenalex.org/work/W3120348535> ?p ?o ?g. }
- W3120348535 endingPage "429" @default.
- W3120348535 startingPage "425" @default.
- W3120348535 abstract "Enzymes play a central role in the detection of target molecules in biotechnological fields. Most probes used in detection are bifunctional proteins comprising enzymes and binding proteins conjugated by chemical reactions. To create a highly sensitive detection probe, it is essential to increase the enzyme-to-binding protein ratio in the probe. However, if the chemical reactions required to prepare the probe are insufficiently site-specific, the detection probe may lose functionality. Genetic modifications and enzyme-mediated post-translational modifications (PTMs) can ensure the site-specific conjugation of proteins. They are therefore promising strategies for the production of detection probes with high enzyme contents, i.e., polymeric bifunctional proteins. Herein, we review recent advances in the preparation of bifunctional protein conjugates and polymeric bifunctional protein conjugates for detection. We have summarized research on genetically fused proteins and enzymatically prepared polymeric bifunctional proteins, and will discuss the potential use of protein polymers in various detection applications." @default.
- W3120348535 created "2021-01-18" @default.
- W3120348535 creator A5037912117 @default.
- W3120348535 creator A5070528489 @default.
- W3120348535 creator A5071257404 @default.
- W3120348535 creator A5072721448 @default.
- W3120348535 date "2021-01-15" @default.
- W3120348535 modified "2023-10-04" @default.
- W3120348535 title "Strategies for Making Multimeric and Polymeric Bifunctional Protein Conjugates and Their Applications as Bioanalytical Tools" @default.
- W3120348535 cites W1554288134 @default.
- W3120348535 cites W1588985038 @default.
- W3120348535 cites W1610740014 @default.
- W3120348535 cites W1965813552 @default.
- W3120348535 cites W1975533902 @default.
- W3120348535 cites W1976672416 @default.
- W3120348535 cites W1980619976 @default.
- W3120348535 cites W1984257235 @default.
- W3120348535 cites W1989521273 @default.
- W3120348535 cites W1990874860 @default.
- W3120348535 cites W1993778132 @default.
- W3120348535 cites W1996192845 @default.
- W3120348535 cites W2020719323 @default.
- W3120348535 cites W2027642775 @default.
- W3120348535 cites W2027933379 @default.
- W3120348535 cites W2030393447 @default.
- W3120348535 cites W2030496099 @default.
- W3120348535 cites W2031726026 @default.
- W3120348535 cites W2032418482 @default.
- W3120348535 cites W2038654759 @default.
- W3120348535 cites W2045498581 @default.
- W3120348535 cites W2048797519 @default.
- W3120348535 cites W2049527800 @default.
- W3120348535 cites W2049928644 @default.
- W3120348535 cites W2050811682 @default.
- W3120348535 cites W2077508172 @default.
- W3120348535 cites W2090187680 @default.
- W3120348535 cites W2092246909 @default.
- W3120348535 cites W2098759156 @default.
- W3120348535 cites W2104725270 @default.
- W3120348535 cites W2126063556 @default.
- W3120348535 cites W2130762696 @default.
- W3120348535 cites W2130781987 @default.
- W3120348535 cites W2161863487 @default.
- W3120348535 cites W2217491058 @default.
- W3120348535 cites W2321667121 @default.
- W3120348535 cites W2328170697 @default.
- W3120348535 cites W2329689827 @default.
- W3120348535 cites W2334153630 @default.
- W3120348535 cites W2336770992 @default.
- W3120348535 cites W2552099501 @default.
- W3120348535 cites W2555146968 @default.
- W3120348535 cites W2561765120 @default.
- W3120348535 cites W2667447087 @default.
- W3120348535 cites W2753997998 @default.
- W3120348535 cites W2760426804 @default.
- W3120348535 cites W2761672813 @default.
- W3120348535 cites W2768553058 @default.
- W3120348535 cites W2789432453 @default.
- W3120348535 cites W2801277161 @default.
- W3120348535 cites W2808041689 @default.
- W3120348535 cites W2808315835 @default.
- W3120348535 cites W2891585482 @default.
- W3120348535 cites W2892900500 @default.
- W3120348535 cites W2893026965 @default.
- W3120348535 cites W2901096543 @default.
- W3120348535 cites W2916514573 @default.
- W3120348535 cites W2921646015 @default.
- W3120348535 cites W2921671486 @default.
- W3120348535 cites W2961848246 @default.
- W3120348535 cites W2994059143 @default.
- W3120348535 cites W3000353147 @default.
- W3120348535 cites W3010213211 @default.
- W3120348535 cites W3017723209 @default.
- W3120348535 cites W3038470619 @default.
- W3120348535 doi "https://doi.org/10.2116/analsci.20scr07" @default.
- W3120348535 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33455962" @default.
- W3120348535 hasPublicationYear "2021" @default.
- W3120348535 type Work @default.
- W3120348535 sameAs 3120348535 @default.
- W3120348535 citedByCount "1" @default.
- W3120348535 countsByYear W31203485352022 @default.
- W3120348535 crossrefType "journal-article" @default.
- W3120348535 hasAuthorship W3120348535A5037912117 @default.
- W3120348535 hasAuthorship W3120348535A5070528489 @default.
- W3120348535 hasAuthorship W3120348535A5071257404 @default.
- W3120348535 hasAuthorship W3120348535A5072721448 @default.
- W3120348535 hasBestOaLocation W31203485351 @default.
- W3120348535 hasConcept C112613896 @default.
- W3120348535 hasConcept C134306372 @default.
- W3120348535 hasConcept C137535248 @default.
- W3120348535 hasConcept C145169222 @default.
- W3120348535 hasConcept C161790260 @default.
- W3120348535 hasConcept C171250308 @default.
- W3120348535 hasConcept C178790620 @default.
- W3120348535 hasConcept C181199279 @default.
- W3120348535 hasConcept C185592680 @default.
- W3120348535 hasConcept C192562407 @default.
- W3120348535 hasConcept C197336794 @default.