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• W3120368655 abstract "Abstract Many industrial microbial enzymes produced currently are used in the food industry. Enzymes are proteins and do not typically represent a hazard. Those that do are well defined and include, bacterial, plant and animal toxins, allergens, and antinutrients. Enzymes are not acutely toxic, genotoxic, or toxic by repeated dose administration. The enzyme industry has performed many genotoxicity studies. Greater than 230 and > 240 mutagenicity studies on bacterial and mammalian cells, respectively have been conducted. Further  > 200, 90-day oral gavage or feeding studies have been performed with no adverse findings observed. Except for the potential skin and eye irritating effects of some proteases and the potential for occupational respiratory sensitization, enzymes are safe for human exposure. These studies also confirm that any remaining fermentation materials in the product also lack toxicity. The safety of enzyme production strains continues to be the key consideration in evaluating enzyme safety. The conduct of repeated toxicological testing with enzymes derived from the same strain lineage with no adverse effects allows for the establishment of a Safe Strain Lineage (SSL). The lack of general toxicological concern on enzymes and the use of the SSL concept support the consideration of reduced Toxicology testing packages. Safety assessment requirements for food enzymes are complicated by differences in global regulations. This includes differences in the conditions under which premarket approval is required, and differences in sensitivities to perceived risks of the use of biotechnology in developing new enzyme products, resulting in discrepancies in the type of safety data manufacturers must provide. Additional research and data into the etiology of how enzymes act as respiratory allergens are also needed to differentiate between nonallergenic/weakly allergenic enzymes and those moderate/strongly allergenic enzymes via the respiratory route of exposure." @default.
• W3120368655 created "2021-01-18" @default.
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• W3120368655 date "2021-01-01" @default.
• W3120368655 modified "2023-09-23" @default.
• W3120368655 title "Safety assessment and regulation of food enzymes" @default.
• W3120368655 cites W1509797374 @default.
• W3120368655 cites W1663451486 @default.
• W3120368655 cites W1965614930 @default.
• W3120368655 cites W1965731359 @default.
• W3120368655 cites W1970504497 @default.
• W3120368655 cites W1972741181 @default.
• W3120368655 cites W1975026685 @default.
• W3120368655 cites W1975569539 @default.
• W3120368655 cites W1976116738 @default.
• W3120368655 cites W1977410756 @default.
• W3120368655 cites W1980297623 @default.
• W3120368655 cites W1983061964 @default.
• W3120368655 cites W1984932103 @default.
• W3120368655 cites W1987920499 @default.
• W3120368655 cites W1989887414 @default.
• W3120368655 cites W1994152414 @default.
• W3120368655 cites W1995769685 @default.
• W3120368655 cites W1996150343 @default.
• W3120368655 cites W1996595637 @default.
• W3120368655 cites W1996673693 @default.
• W3120368655 cites W1996706124 @default.
• W3120368655 cites W1999440283 @default.
• W3120368655 cites W1999977876 @default.
• W3120368655 cites W2002925916 @default.
• W3120368655 cites W2004590673 @default.
• W3120368655 cites W2012019289 @default.
• W3120368655 cites W2012037212 @default.
• W3120368655 cites W2014394070 @default.
• W3120368655 cites W2017864034 @default.
• W3120368655 cites W2018485866 @default.
• W3120368655 cites W2028622989 @default.
• W3120368655 cites W2033160596 @default.
• W3120368655 cites W2033275522 @default.
• W3120368655 cites W2036687270 @default.
• W3120368655 cites W2037643116 @default.
• W3120368655 cites W2041618773 @default.
• W3120368655 cites W2047429219 @default.
• W3120368655 cites W2055961998 @default.
• W3120368655 cites W2066212396 @default.
• W3120368655 cites W2066810034 @default.
• W3120368655 cites W2071201153 @default.
• W3120368655 cites W2074060578 @default.
• W3120368655 cites W2074652661 @default.
• W3120368655 cites W2079068183 @default.
• W3120368655 cites W2083068485 @default.
• W3120368655 cites W2084904413 @default.
• W3120368655 cites W2089433326 @default.
• W3120368655 cites W2090008197 @default.
• W3120368655 cites W2090717906 @default.
• W3120368655 cites W2091446179 @default.
• W3120368655 cites W2091487197 @default.
• W3120368655 cites W2092324299 @default.
• W3120368655 cites W2099872676 @default.
• W3120368655 cites W2101575777 @default.
• W3120368655 cites W2103810448 @default.
• W3120368655 cites W2105128860 @default.
• W3120368655 cites W2110185376 @default.
• W3120368655 cites W2120613001 @default.
• W3120368655 cites W2128750672 @default.
• W3120368655 cites W2131746549 @default.
• W3120368655 cites W2149401228 @default.
• W3120368655 cites W2155540630 @default.
• W3120368655 cites W2158700061 @default.
• W3120368655 cites W2162242518 @default.
• W3120368655 cites W2281797260 @default.
• W3120368655 cites W2480250600 @default.
• W3120368655 cites W2558829876 @default.
• W3120368655 cites W2559506619 @default.
• W3120368655 cites W2560636839 @default.
• W3120368655 cites W2598158548 @default.
• W3120368655 cites W2725470504 @default.
• W3120368655 cites W2745259129 @default.
• W3120368655 cites W2766999394 @default.
• W3120368655 cites W2883679222 @default.
• W3120368655 cites W2884103334 @default.
• W3120368655 cites W2892516129 @default.
• W3120368655 cites W2913880965 @default.
• W3120368655 cites W3015965575 @default.
• W3120368655 cites W3033170284 @default.
• W3120368655 cites W4211140833 @default.
• W3120368655 cites W4233295295 @default.
• W3120368655 cites W4241259814 @default.
• W3120368655 cites W4245787816 @default.
• W3120368655 cites W4248163749 @default.
• W3120368655 cites W4248367258 @default.
• W3120368655 doi "https://doi.org/10.1016/b978-0-12-800217-9.00008-3" @default.
• W3120368655 hasPublicationYear "2021" @default.
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