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- W3120402006 abstract "Bathymodiolinae mussels are dominant species in cold seeps and hydrothermal vents and could harbor endosymbionts in gill bacteriocytes. However, mechanisms underlying the symbiosis have remained largely undisclosed for years. In the present study, the global expression pattern of immune-related genes and miRNAs were surveyed in Gigantidas platifrons during bacterial challenges using enriched symbiotic methane oxidation bacteria MOBs or nonsymbiotic Vibrio. As a result, multiple pattern recognition receptors were found differentially expressed at 12 h and 24 h post bacteria challenges and distinctly clustered between stimulations. Dozens of immune effectors along with signal transducers were also modulated simultaneously during MOB or Vibrio challenge. A total of 459 miRNAs were identified in the gill while some were differentially expressed post MOB or nonsymbiotic bacteria challenge. A variety of immune-related genes were annotated as target genes of aforesaid differentially expressed miRNAs. As a result, biological processes including the immune recognition, lysosome activity and bacteria engulfment were suggested to be dynamically modulated by miRNAs in either symbiotic or nonsymbiotic bacteria challenge. It was suggested that G. platifrons mussels could maintain a robust immune response against invading pathogens while establishing symbiosis with chemosynthetic bacteria with the orchestra of immune-related genes and miRNAs." @default.
- W3120402006 created "2021-01-18" @default.
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- W3120402006 date "2021-12-01" @default.
- W3120402006 modified "2023-10-16" @default.
- W3120402006 title "microRNAs facilitate comprehensive responses of Bathymodiolinae mussel against symbiotic and nonsymbiotic bacteria stimulation" @default.
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- W3120402006 cites W1861268613 @default.
- W3120402006 cites W1965027165 @default.
- W3120402006 cites W1965804961 @default.
- W3120402006 cites W1972053399 @default.
- W3120402006 cites W1973527107 @default.
- W3120402006 cites W1977260572 @default.
- W3120402006 cites W1981500674 @default.
- W3120402006 cites W1984438138 @default.
- W3120402006 cites W1986338358 @default.
- W3120402006 cites W1987320140 @default.
- W3120402006 cites W1996540389 @default.
- W3120402006 cites W2002213182 @default.
- W3120402006 cites W2015884530 @default.
- W3120402006 cites W2020969008 @default.
- W3120402006 cites W2021051229 @default.
- W3120402006 cites W2023692023 @default.
- W3120402006 cites W2023941297 @default.
- W3120402006 cites W2026345779 @default.
- W3120402006 cites W2031006708 @default.
- W3120402006 cites W2032822024 @default.
- W3120402006 cites W2039478038 @default.
- W3120402006 cites W2040846235 @default.
- W3120402006 cites W2043433277 @default.
- W3120402006 cites W2054506758 @default.
- W3120402006 cites W2063513932 @default.
- W3120402006 cites W2074964253 @default.
- W3120402006 cites W2075127796 @default.
- W3120402006 cites W2076492129 @default.
- W3120402006 cites W2081725145 @default.
- W3120402006 cites W2084271278 @default.
- W3120402006 cites W2089545133 @default.
- W3120402006 cites W2092274918 @default.
- W3120402006 cites W2094025714 @default.
- W3120402006 cites W2104329297 @default.
- W3120402006 cites W2111963976 @default.
- W3120402006 cites W2116690382 @default.
- W3120402006 cites W2117890374 @default.
- W3120402006 cites W2124078080 @default.
- W3120402006 cites W2124609728 @default.
- W3120402006 cites W2126740791 @default.
- W3120402006 cites W2135662322 @default.
- W3120402006 cites W2136243038 @default.
- W3120402006 cites W2138497186 @default.
- W3120402006 cites W2146934798 @default.
- W3120402006 cites W2154768046 @default.
- W3120402006 cites W2160906644 @default.
- W3120402006 cites W2162674813 @default.
- W3120402006 cites W2164813052 @default.
- W3120402006 cites W2166410860 @default.
- W3120402006 cites W2166781237 @default.
- W3120402006 cites W2170856052 @default.
- W3120402006 cites W2202975480 @default.
- W3120402006 cites W2224810324 @default.
- W3120402006 cites W2341683385 @default.
- W3120402006 cites W2402177553 @default.
- W3120402006 cites W2490217535 @default.
- W3120402006 cites W2548512960 @default.
- W3120402006 cites W2588672464 @default.
- W3120402006 cites W2604169503 @default.
- W3120402006 cites W2608285012 @default.
- W3120402006 cites W2610092639 @default.
- W3120402006 cites W2738296357 @default.
- W3120402006 cites W2753603458 @default.
- W3120402006 cites W2753859002 @default.
- W3120402006 cites W2776975753 @default.
- W3120402006 cites W2782914881 @default.
- W3120402006 cites W2888608612 @default.
- W3120402006 cites W2894422127 @default.
- W3120402006 cites W2894768040 @default.
- W3120402006 cites W2920922131 @default.
- W3120402006 cites W2940310137 @default.
- W3120402006 cites W2962063376 @default.
- W3120402006 cites W2965951146 @default.
- W3120402006 cites W2968557966 @default.
- W3120402006 cites W3150469150 @default.
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- W3120402006 doi "https://doi.org/10.1016/j.fsi.2021.10.025" @default.
- W3120402006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34687882" @default.
- W3120402006 hasPublicationYear "2021" @default.
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